mlsanityData to 7 Oct 2026

Adapting Neural Networks for the Estimation of Treatment Effects

arXiv 1906.02120 ↗First posted 5 Jun 2019stat.ML cs.LG stat.MEcited by 285

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Abstract (arXiv)

This paper addresses the use of neural networks for the estimation of treatment effects from observational data. Generally, estimation proceeds in two stages. First, we fit models for the expected outcome and the probability of treatment (propensity score) for each unit. Second, we plug these fitted models into a downstream estimator of the effect. Neural networks are a natural choice for the models in the first step. The question we address is: how can we adapt the design and training of the neural networks used in the first step in order to improve the quality of the final estimate of the treatment effect? We propose two adaptations based on insights from the statistical literature on the estimation of treatment effects. The first is a new architecture, the Dragonnet, that exploits the sufficiency of the propensity score for estimation adjustment. The second is a regularization procedure, targeted regularization, that induces a bias towards models that have non-parametrically optimal asymptotic properties `out-of-the-box`. Studies on benchmark datasets for causal inference show these adaptations outperform existing methods. Code is available at github.com/claudiashi57/dragonnet.

Key facts. Cited by 285 papers in the map (data through 7 Oct 2026). First posted on arXiv 5 Jun 2019.

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Citing papers per year: 2021: 28; 2022: 44; 2023: 47; 2024: 63; 2025: 65; 2026: 38.

285 papers.

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  1. 2021Nonparametric Estimation of Heterogeneous Treatment Effects: From Theory to Learning Algorithmscited by 144
  2. 2021The Causal-Neural Connection: Expressiveness, Learnability, and Inferencecited by 97
  3. 2022Diffusion Causal Models for Counterfactual Estimationcited by 87
  4. 2021On Inductive Biases for Heterogeneous Treatment Effect Estimationcited by 74
  5. 2024Causal machine learning for predicting treatment outcomescited by 73
  6. 2021VCNet and Functional Targeted Regularization For Learning Causal Effects of Continuous Treatmentscited by 59
  7. 2022Neural Causal Models for Counterfactual Identification and Estimationcited by 54
  8. 2025Do-PFN: In-Context Learning for Causal Effect Estimationcited by 46
  9. 2025CausalPFN: Amortized Causal Effect Estimation via In-Context Learningcited by 43
  10. 2021RieszNet and ForestRiesz: Automatic Debiased Machine Learning with Neural Nets and Random Forestscited by 42
  11. 2021Conditional Distributional Treatment Effect with Kernel Conditional Mean Embeddings and U-Statistic Regressioncited by 40
  12. 2021Causal Effect Inference for Structured Treatmentscited by 38
38 more
  1. 2023Measuring axiomatic soundness of counterfactual image modelscited by 34
  2. 2023Optimal Transport for Treatment Effect Estimationcited by 32
  3. 2025Foundation Models for Causal Inference via Prior-Data Fitted Networkscited by 30
  4. 2021A Critical Look at the Consistency of Causal Estimation With Deep Latent Variable Modelscited by 29
  5. 2022Estimating average causal effects from patient trajectoriescited by 29
  6. 2021Causal-BALD: Deep Bayesian Active Learning of Outcomes to Infer Treatment-Effects from Observational Datacited by 27
  7. 2021Estimating Average Treatment Effects via Orthogonal Regularizationcited by 25
  8. 2021SurvITE: Learning Heterogeneous Treatment Effects from Time-to-Event Datacited by 25
  9. 2022Exploring Transformer Backbones for Heterogeneous Treatment Effect Estimationcited by 25
  10. 2022Empirical Analysis of Model Selection for Heterogeneous Causal Effect Estimationcited by 25
  11. 2023Explicit Feature Interaction-aware Uplift Network for Online Marketingcited by 25
  12. 2023Sharp Bounds for Generalized Causal Sensitivity Analysiscited by 24
  13. 2021Algorithm Fairness in AI for Medicine and Healthcarecited by 21
  14. 2022Normalizing Flows for Interventional Density Estimationcited by 21
  15. 2023Unbiased Scene Graph Generation via Two-stage Causal Modelingcited by 21
  16. 2022Scalable Sensitivity and Uncertainty Analysis for Causal-Effect Estimates of Continuous-Valued Interventionscited by 20
  17. 2024Doubly Robust Causal Effect Estimation under Networked Interference via Targeted Learningcited by 19
  18. 2021Estimating Categorical Counterfactuals via Deep Twin Networkscited by 18
  19. 2022TDR-CL: Targeted Doubly Robust Collaborative Learning for Debiased Recommendationscited by 18
  20. 2022Robust and Agnostic Learning of Conditional Distributional Treatment Effectscited by 18
  21. 2023Zero-shot causal learningcited by 17
  22. 2023Towards Causal Foundation Model: on Duality between Causal Inference and Attentioncited by 17
  23. 2023A Neural Framework for Generalized Causal Sensitivity Analysiscited by 17
  24. 2022DESCN: Deep Entire Space Cross Networks for Individual Treatment Effect Estimationcited by 16
  25. 2024Causal Inference with Generative Artificial Intelligence: Application to Texts as Treatmentscited by 16
  26. 2022Causal Estimation for Text Data with (Apparent) Overlap Violationscited by 15
  27. 2023Reliable Off-Policy Learning for Dosage Combinationscited by 15
  28. 2023Causal Effect Estimation: Recent Advances, Challenges, and Opportunitiescited by 14
  29. 2022Deep Multi-Modal Structural Equations For Causal Effect Estimation With Unstructured Proxiescited by 13
  30. 2024Rankability-enhanced Revenue Uplift Modeling Framework for Online Marketingcited by 12
  31. 2022Estimating counterfactual treatment outcomes over time in complex multiagent scenarioscited by 11
  32. 2022Deep Causal Learning: Representation, Discovery and Inferencecited by 11
  33. 2023Dynamic Inter-treatment Information Sharing for Individualized Treatment Effects Estimationcited by 11
  34. 2024Meta-Learners for Partially-Identified Treatment Effects Across Multiple Environmentscited by 11
  35. 2025Doubly Robust Alignment for Large Language Modelscited by 11
  36. 2021Intact-VAE: Estimating Treatment Effects under Unobserved Confoundingcited by 10
  37. 2021Finding Valid Adjustments under Non-ignorability with Minimal DAG Knowledgecited by 10
  38. 2022Partial Identification with Noisy Covariates: A Robust Optimization Approachcited by 10

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