Supervised Learning Objectives for High-Dimensional Treatment Effects

Predicting the effect of interventions with many possible variations, e.g., therapeutic content that affects mental health outcomes or an earnings call transcript that drives movement in share price, is useful across several domains. However, classical causal estimators tend to assume that all possible interventions are observed, which is infeasible when interventions vary widely, for instance, in the space of all text strings. We adapt a well-known approach of recasting causal inference as a learning problem to address such settings, assuming realizability of the learned function and no unobserved confounding. We show that causal error decomposes into moment-balancing errors of increasing order and exploit structure of the conditional outcome in the confounders to design objectives that directly improve causal estimation. We also show how to project the effect of a high-dimensional treatment onto coarser attributes, which allows a single model to answer several causal questions without additional attribute-specific training. We empirically evaluate our estimators in settings with high-dimensional continuous, discrete, and text treatments. Our experiments demonstrate generalization to held-out treatments, benefits of balancing higher-order moments when required, and projected causal estimates that are competitive with attribute-specific ones.