Splitting the Difference: Interpretable Causal Forests for Treatment Effect Heterogeneity and Bias
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Abstract (arXiv)
In various fields, such as medicine and marketing, accurately predicting individual treatment effects holds significant promise. However, achieving reliable predictions alone is often insufficient for making informed decisions; it is equally important to understand why the treatment effect is higher for some individuals than for others. To address this two-fold challenge of prediction and interpretation, we introduce an algorithm based on decision trees and random forests for estimating individual treatment effects. Our algorithm is simple: it operates exactly like a standard random forest, but with a different splitting criterion, and requires no additional workarounds such as double machine learning or orthogonalization as used in Generalized random forests. It handles observational studies with varying treatment propensities without requiring separate estimation of the full propensity function. This is achieved by combining two splitting criteria---one targeting heterogeneity in the treatment effect, the other targeting bias correction for the average treatment effect---which together improve split point selection and automatically distinguish confounders from features responsible for heterogeneity. As a result, interpretation follows directly from the fitted tree structure itself, that is, from which features the trees split on and with which split statistics, without requiring separate post-hoc analysis. For the theoretical analysis of this algorithm, we consider a change point model with step functions for potential outcomes and treatment propensity and provide insights into the theoretical underpinnings of our approach. Simulation studies show that our simple algorithm achieves comparable, and often better, prediction accuracy than existing methods, while substantially improving interpretability.
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References · 15
- 2015Estimation and Inference of Heterogeneous Treatment Effects using Random Forestscited by 597
- 2017Meta-learners for Estimating Heterogeneous Treatment Effects using Machine Learningcited by 475
- 2016Generalized Random Forestscited by 309
- 2019Adapting Neural Networks for the Estimation of Treatment Effectscited by 285
- 2015Recursive Partitioning for Heterogeneous Causal Effectscited by 254
- 2021Nonparametric Estimation of Heterogeneous Treatment Effects: From Theory to Learning Algorithmscited by 144
- 2017Automated versus do-it-yourself methods for causal inference: Lessons learned from a data analysis competitioncited by 106
- 2018Orthogonal Random Forest for Causal Inferencecited by 51
- 2020RealCause: Realistic Causal Inference Benchmarkingcited by 44
- 2025CausalPFN: Amortized Causal Effect Estimation via In-Context Learningcited by 43
- 2017Iterative Random Forests to detect predictive and stable high-order interactionscited by 42
- 2019Unbiased Measurement of Feature Importance in Tree-Based Methodscited by 30
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