mlsanityData to 7 Oct 2026

Fast inference of deep neural networks in FPGAs for particle physics

arXiv 1804.06913 ↗First posted 16 Apr 2018physics.ins-det cs.CV hep-excited by 132

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Abstract (arXiv)

Recent results at the Large Hadron Collider (LHC) have pointed to enhanced physics capabilities through the improvement of the real-time event processing techniques. Machine learning methods are ubiquitous and have proven to be very powerful in LHC physics, and particle physics as a whole. However, exploration of the use of such techniques in low-latency, low-power FPGA hardware has only just begun. FPGA-based trigger and data acquisition (DAQ) systems have extremely low, sub-microsecond latency requirements that are unique to particle physics. We present a case study for neural network inference in FPGAs focusing on a classifier for jet substructure which would enable, among many other physics scenarios, searches for new dark sector particles and novel measurements of the Higgs boson. While we focus on a specific example, the lessons are far-reaching. We develop a package based on High-Level Synthesis (HLS) called hls4ml to build machine learning models in FPGAs. The use of HLS increases accessibility across a broad user community and allows for a drastic decrease in firmware development time. We map out FPGA resource usage and latency versus neural network hyperparameters to identify the problems in particle physics that would benefit from performing neural network inference with FPGAs. For our example jet substructure model, we fit well within the available resources of modern FPGAs with a latency on the scale of 100 ns.

Key facts. Cited by 132 papers in the map (data through 7 Oct 2026). First posted on arXiv 16 Apr 2018.

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Citing papers per year: 2021: 21; 2022: 23; 2023: 15; 2024: 22; 2025: 25; 2026: 26.

132 papers.

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  1. 2021Distributed Learning in Wireless Networks: Recent Progress and Future Challengescited by 125
  2. 2021A Living Review of Machine Learning for Particle Physicscited by 77
  3. 2021hls4ml: An Open-Source Codesign Workflow to Empower Scientific Low-Power Machine Learning Devicescited by 61
  4. 2021Machine Learning in the Search for New Fundamental Physicscited by 50
  5. 2021Fast convolutional neural networks on FPGAs with hls4mlcited by 42
  6. 2021MLPF: Efficient machine-learned particle-flow reconstruction using graph neural networkscited by 36
  7. 2021Applications and Techniques for Fast Machine Learning in Sciencecited by 32
  8. 2021Ps and Qs: Quantization-aware pruning for efficient low latency neural network inferencecited by 31
  9. 2023PolyLUT: Learning Piecewise Polynomials for Ultra-Low Latency FPGA LUT-based Inferencecited by 30
  10. 2023Machine Learning for Anomaly Detection in Particle Physicscited by 29
  11. 2024Differentiable Weightless Neural Networkscited by 27
  12. 2021Point Cloud Transformers applied to Collider Physicscited by 23
38 more
  1. 2023Explainable Equivariant Neural Networks for Particle Physics: PELICANcited by 22
  2. 2022Random matrix analysis of deep neural network weight matricescited by 21
  3. 2024NeuraLUT: Hiding Neural Network Density in Boolean Synthesizable Functionscited by 21
  4. 2021A reconfigurable neural network ASIC for detector front-end data compression at the HL-LHCcited by 20
  5. 2021Charged particle tracking via edge-classifying interaction networkscited by 19
  6. 2021Graph Neural Networks for Charged Particle Tracking on FPGAscited by 17
  7. 2024Allo: A Programming Model for Composable Accelerator Designcited by 16
  8. 2021Online-compatible Unsupervised Non-resonant Anomaly Detectioncited by 15
  9. 2022Ultra-low latency recurrent neural network inference on FPGAs for physics applications with hls4mlcited by 14
  10. 2025NeuraLUT-Assemble: Hardware-aware Assembling of Sub-Neural Networks for Efficient LUT Inferencecited by 14
  11. 2021Reliably-stabilizing piecewise-affine neural network controllerscited by 13
  12. 2021Accelerating Recurrent Neural Networks for Gravitational Wave Experimentscited by 12
  13. 2022Weightless Neural Networks for Efficient Edge Inferencecited by 12
  14. 2022Graph Neural Networks in Particle Physics: Implementations, Innovations, and Challengescited by 12
  15. 2022Single-Shot Optical Neural Networkcited by 12
  16. 2022FastML Science Benchmarks: Accelerating Real-Time Scientific Edge Machine Learningcited by 12
  17. 2022LL-GNN: Low Latency Graph Neural Networks on FPGAs for High Energy Physicscited by 12
  18. 2024Ultrafast jet classification on FPGAs for the HL-LHCcited by 12
  19. 2024PolyLUT-Add: FPGA-based LUT Inference with Wide Inputscited by 12
  20. 2022Real-time semantic segmentation on FPGAs for autonomous vehicles with hls4mlcited by 11
  21. 2022Snowmass 2021 Computational Frontier CompF03 Topical Group Report: Machine Learningcited by 10
  22. 2021Nanosecond machine learning event classification with boosted decision trees in FPGA for high energy physicscited by 9
  23. 2022Boundary between noise and information applied to filtering neural network weight matricescited by 9
  24. 2022QONNX: Representing Arbitrary-Precision Quantized Neural Networkscited by 9
  25. 2022Open-source FPGA-ML codesign for the MLPerf Tiny Benchmarkcited by 9
  26. 2024HGQ: High Granularity Quantization for Real-time Neural Networks on FPGAscited by 9
  27. 2023Within-Camera Multilayer Perceptron DVS Denoisingcited by 8
  28. 2025PolyLUT: Ultra-low Latency Polynomial Inference with Hardware-Aware Structured Pruningcited by 8
  29. 2025End-to-end workflow for machine learning-based qubit readout with QICK and hls4mlcited by 8
  30. 2025hls4ml: A Flexible, Open-Source Platform for Deep Learning Acceleration on Reconfigurable Hardwarecited by 8
  31. 2022Explainable AI for High Energy Physicscited by 7
  32. 2023FPGA Resource-aware Structured Pruning for Real-Time Neural Networkscited by 7
  33. 2022Reducing Computational Complexity of Neural Networks in Optical Channel Equalization: From Concepts to Implementationcited by 6
  34. 2022A Detailed Study of Interpretability of Deep Neural Network based Top Taggerscited by 6
  35. 2023Tailor: Altering Skip Connections for Resource-Efficient Inferencecited by 6
  36. 2023Fast Particle-based Anomaly Detection Algorithm with Variational Autoencodercited by 6
  37. 2024SymbolNet: Neural Symbolic Regression with Adaptive Dynamic Pruning for Compressioncited by 6
  38. 2024Ultra Fast Transformers on FPGAs for Particle Physics Experimentscited by 6

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