KinTwin: Imitation Learning with Torque and Muscle Driven Biomechanical Models Enables Precise Replication of Able-Bodied and Impaired Movement from Markerless Motion Capture

Broader access to high-quality movement analysis could greatly benefit movement science and rehabilitation, such as allowing more detailed characterization of movement impairments and responses to interventions, or even enabling early detection of new neurological conditions or fall risk. While emerging technologies are making it easier to capture kinematics with biomechanical models, or how joint angles change over time, inferring the underlying physics that give rise to these movements, including ground reaction forces, joint torques, or even muscle activations, is still challenging. Here we explore whether imitation learning applied to a biomechanical model from a large dataset of movements from able-bodied and impaired individuals can learn to compute these inverse dynamics. Although imitation learning in human pose estimation has seen great interest in recent years, our work differences in several ways: we focus on using an accurate biomechanical model instead of models adopted for computer vision, we test it on a dataset that contains participants with impaired movements, we reported detailed tracking metrics relevant for the clinical measurement of movement including joint angles and ground contact events, and finally we apply imitation learning to a muscle-driven neuromusculoskeletal model. We show that our imitation learning policy, KinTwin, can accurately replicate the kinematics of a wide range of movements, including those with assistive devices or therapist assistance, and that it can infer clinically meaningful differences in joint torques and muscle activations. Our work demonstrates the potential for using imitation learning to enable high-quality movement analysis in clinical practice.