mlsanityData to 7 Oct 2026

Embracing Trustworthy Brain-Agent Collaboration as Paradigm Extension for Intelligent Assistive Technologies

arXiv 2510.22095 ↗First posted 25 Oct 2025cs.AI cs.CLcited by 5

On the map: LLM agents and tool use → Medical and scientific domain agents

Abstract (arXiv)

Brain-Computer Interfaces (BCIs) offer a direct communication pathway between the human brain and external devices, holding significant promise for individuals with severe neurological impairments. However, their widespread adoption is hindered by critical limitations, such as low information transfer rates and extensive user-specific calibration. To overcome these challenges, recent research has explored the integration of Large Language Models (LLMs), extending the focus from simple command decoding to understanding complex cognitive states. Despite these advancements, deploying agentic AI faces technical hurdles and ethical concerns. Due to the lack of comprehensive discussion on this emerging direction, this position paper argues that the field is poised for a paradigm extension from BCI to Brain-Agent Collaboration (BAC). We emphasize reframing agents as active and collaborative partners for intelligent assistance rather than passive brain signal data processors, demanding a focus on ethical data handling, model reliability, and a robust human-agent collaboration framework to ensure these systems are safe, trustworthy, and effective.

Key facts. Cited by 5 papers in the map (data through 7 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 69 of its 128 references that are in the map. First posted on arXiv 25 Oct 2025.

Builds on

69 of 128 references.

Closest ancestors · 2

Same direction, newest first

  1. 2025A Survey of LLM-based Agents in Medicine: How far are we from Baymax?16 Feb
  2. 2025Hallucination Mitigation using Agentic AI Natural Language-Based Frameworks19 Jan

Other references · 67

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  11. 2023A Survey on Hallucination in Large Language Models: Principles, Taxonomy, Challenges, and Open Questionscited by 1,582
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  12. 2025From Web Search towards Agentic Deep Research: Incentivizing Search with Reasoning Agentscited by 49
  13. 2017Machine learning for neural decodingcited by 45
  14. 2025A Survey on the Optimization of Large Language Model-based Agentscited by 45
  15. 2025Towards Agentic RAG with Deep Reasoning: A Survey of RAG-Reasoning Systems in LLMscited by 40
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  20. 2024Measuring and Reducing LLM Hallucination without Gold-Standard Answerscited by 31
  21. 2024Evaluating Human-AI Collaboration: A Review and Methodological Frameworkcited by 25
  22. 2025RECODE-H: A Benchmark for Research Code Development with Interactive Human Feedbackcited by 24
  23. 2025Brain Foundation Models: A Survey on Advancements in Neural Signal Processing and Brain Discoverycited by 22
  24. 2025Multi-Agent Autonomous Driving Systems with Large Language Models: A Survey of Recent Advancescited by 21
  25. 2024EEG2TEXT: Open Vocabulary EEG-to-Text Decoding with EEG Pre-Training and Multi-View Transformercited by 19
  26. 2025AI Agents: Evolution, Architecture, and Real-World Applicationscited by 19
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  28. 2024Enhancing EEG-to-Text Decoding through Transferable Representations from Pre-trained Contrastive EEG-Text Masked Autoencodercited by 15
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  35. 2023Deep Representation Learning for Open Vocabulary Electroencephalography-to-Text Decodingcited by 9
  36. 2025Multi-Agent Systems for Robotic Autonomy with LLMscited by 9
  37. 2025A Call for Collaborative Intelligence: Why Human-Agent Systems Should Precede AI Autonomycited by 9
  38. 2023BrainLLM: Generative Language Decoding from Brain Recordingscited by 7

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2026: 5.

5 papers.

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