Embracing Trustworthy Brain-Agent Collaboration as Paradigm Extension for Intelligent Assistive Technologies
On the map: LLM agents and tool use → Medical and scientific domain agents
Abstract (arXiv)
Brain-Computer Interfaces (BCIs) offer a direct communication pathway between the human brain and external devices, holding significant promise for individuals with severe neurological impairments. However, their widespread adoption is hindered by critical limitations, such as low information transfer rates and extensive user-specific calibration. To overcome these challenges, recent research has explored the integration of Large Language Models (LLMs), extending the focus from simple command decoding to understanding complex cognitive states. Despite these advancements, deploying agentic AI faces technical hurdles and ethical concerns. Due to the lack of comprehensive discussion on this emerging direction, this position paper argues that the field is poised for a paradigm extension from BCI to Brain-Agent Collaboration (BAC). We emphasize reframing agents as active and collaborative partners for intelligent assistance rather than passive brain signal data processors, demanding a focus on ethical data handling, model reliability, and a robust human-agent collaboration framework to ensure these systems are safe, trustworthy, and effective.
Key facts. Cited by 5 papers in the map (data through 7 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 69 of its 128 references that are in the map. First posted on arXiv 25 Oct 2025.
Builds on
69 of 128 references.
Closest ancestors · 2
Same direction, newest first
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