mlsanityData to 14 Oct 2026

BrainAgent: A Large Language Model-Driven Multi-Agent Framework for Autonomous Brain Signal Understanding

arXiv 2606.25400 ↗First posted 24 Jun 2026cs.AIcited by 3

On the map: LLM agents and tool use → Medical and scientific domain agents

Abstract (arXiv)

Brain-Computer Interfaces (BCIs) and brain signal understanding are pivotal for clinical health and next-generation interactions. Despite this significance, its widespread adoption in real-world scenarios remains restricted, primarily because current analytical paradigms lack sufficient agentic intelligence. First, existing methodologies impose prohibitive technical barriers, requiring extensive specialized expertise. Second, they remain inherently static and task-specific, failing to execute the complex, long-horizon workflows essential for real-world deployment. To accelerate the democratization of brain signal understanding, we draw inspiration from Large Language Models (LLMs) to introduce BrainAgent, an LLM-driven multi-agent framework designed to ground abstract natural language intent into rigorous, executable, and end-to-end processing pipelines. BrainAgent employs a hierarchical architecture where a central supervisor orchestrates specialized sub-agents for adaptive task decomposition and execution. Furthermore, we establish a comprehensive, systematic benchmark for evaluating agentic systems in brain signal analysis. Empirical results demonstrate that BrainAgent effectively automates complex workflows with superior reliability, marking a paradigm shift toward democratized brain signal understanding.

Key facts. Cited by 3 papers in the map (data through 14 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 23 of its 64 references that are in the map. First posted on arXiv 24 Jun 2026.

Builds on

23 of 64 references.

Closest ancestors · 4

Same direction, newest first

  1. 2025Embracing Trustworthy Brain-Agent Collaboration as Paradigm Extension for Intelligent Assistive Technologies25 Oct
  2. 2025A Survey of LLM-based Agents in Medicine: How far are we from Baymax?16 Feb
  3. 2024ChemToolAgent: The Impact of Tools on Language Agents for Chemistry Problem Solving11 Nov
  4. 2024CellAgent: An LLM-driven Multi-Agent Framework for Automated Single-cell Data Analysis13 Jul

Other references · 19

  1. 2020Language Models are Few-Shot Learnerscited by 32,419
  2. 2022Training language models to follow instructions with human feedbackcited by 15,971
  3. 2025Qwen3 Technical Reportcited by 8,820
  4. 2022ReAct: Synergizing Reasoning and Acting in Language Modelscited by 8,695
  5. 2023Toolformer: Language Models Can Teach Themselves to Use Toolscited by 4,182
  6. 2022WebShop: Towards Scalable Real-World Web Interaction with Grounded Language Agentscited by 1,251
  7. 2023ChemCrow: Augmenting large-language models with chemistry toolscited by 631
  8. 2016EEGNet: A Compact Convolutional Network for EEG-based Brain-Computer Interfacescited by 628
  9. 2024Understanding the planning of LLM agents: A surveycited by 421
  10. 2024CBraMod: A Criss-Cross Brain Foundation Model for EEG Decodingcited by 199
  11. 2021Open Vocabulary Electroencephalography-To-Text Decoding and Zero-shot Sentiment Classificationcited by 67
  12. 2022Transformer Convolutional Neural Networks for Automated Artifact Detection in Scalp EEGcited by 55
7 more
  1. 2022EEG based Emotion Recognition: A Tutorial and Reviewcited by 43
  2. 2020Inter-database validation of a deep learning approach for automatic sleep scoringcited by 38
  3. 2023EEG2IMAGE: Image Reconstruction from EEG Brain Signalscited by 30
  4. 2025NeuroChat: A Neuroadaptive AI Chatbot for Customizing Learning Experiencescited by 11
  5. 2022A Framework for Preserving Privacy and Cybersecurity in Brain-Computer Interfacing Applicationscited by 4
  6. 2024Human-AI Teaming Using Large Language Models: Boosting Brain-Computer Interfacing (BCI) and Brain Researchcited by 3
  7. 2025EMOD: A Unified EEG Emotion Representation Framework Leveraging V-A Guided Contrastive Learningcited by 2

Built on by

Cited by year (2026 to 14 Oct)

Citing papers per year: 2026: 3.

3 papers.

Similar, not cited

Close in wording, no citation either way

  1. 2026NS-Copilot: An LLM-Driven Agent System for Autonomous Neuroscience Analysis
  2. 2026When Language Models Meet NeuroGraphs: Exploring Enhanced Agentic LLM Framework Towards Brain Network Analysis
  3. 2026BrainPilot: Automating Brain Discovery with Agentic Research
  4. 2026NeuroAgent: LLM Agents for Multimodal Neuroimaging Analysis and Research
  5. 2025Advances and Challenges in Foundation Agents: From Brain-Inspired Intelligence to Evolutionary, Collaborative, and Safe Systems
  6. 2026AutoBCI: Forecast-Guided Agentic Neural Architecture Discovery for EEG-Based Brain--Computer Interfaces
  7. 2026Multi-Modal Multi-Agent Robotic Cognitive Alignment enabled by Non-Invasive Consumer Brain Computer Interfaces: A Proof of Concept Exploration
  8. 2025BriLLM: Brain-inspired Large Language Model