Segment Anything in Medical Images and Videos: Benchmark and Deployment
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Abstract (arXiv)
Recent advances in segmentation foundation models have enabled accurate and efficient segmentation across a wide range of natural images and videos, but their utility to medical data remains unclear. In this work, we first present a comprehensive benchmarking of the Segment Anything Model 2 (SAM2) across 11 medical image modalities and videos and point out its strengths and weaknesses by comparing it to SAM1 and MedSAM. Then, we develop a transfer learning pipeline and demonstrate SAM2 can be quickly adapted to medical domain by fine-tuning. Furthermore, we implement SAM2 as a 3D slicer plugin and Gradio API for efficient 3D image and video segmentation. The code has been made publicly available at urlhttps://github.com/bowang-lab/MedSAM.
Key facts. Cited by 42 papers in the map (data through 14 Oct 2026). Builds on 33 of its 55 references that are in the map. First posted on arXiv 6 Aug 2024.
Builds on
33 of 55 references.
References · 33
- 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 30,186
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,713
- 2023Segment Anythingcited by 8,234
- 2014Fully Convolutional Networks for Semantic Segmentationcited by 4,859
- 2021On the Opportunities and Risks of Foundation Modelscited by 4,033
- 2024SAM 2: Segment Anything in Images and Videoscited by 2,863
- 2024Grounded SAM: Assembling Open-World Models for Diverse Visual Taskscited by 929
- 2023Segment Everything Everywhere All at Oncecited by 548
- 2018Identifying the Best Machine Learning Algorithms for Brain Tumor Segmentation, Progression Assessment, and Overall Survival Prediction in the BRATS Challengecited by 511
- 2019The Liver Tumor Segmentation Benchmark (LiTS)cited by 509
- 2023Segment Anything in High Qualitycited by 376
- 2023Segment Anything Model for Medical Image Analysis: an Experimental Studycited by 291
21 more
- 2023Hiera: A Hierarchical Vision Transformer without the Bells-and-Whistlescited by 290
- 2019Embracing Imperfect Datasets: A Review of Deep Learning Solutions for Medical Image Segmentationcited by 260
- 2019Deep Learning for Segmentation using an Open Large-Scale Dataset in 2D Echocardiographycited by 244
- 2020AbdomenCT-1K: Is Abdominal Organ Segmentation A Solved Problem?cited by 224
- 2019The state of the art in kidney and kidney tumor segmentation in contrast-enhanced CT imaging: Results of the KiTS19 Challengecited by 190
- 2019Gradio: Hassle-Free Sharing and Testing of ML Models in the Wildcited by 178
- 2024Medical SAM 2: Segment medical images as video via Segment Anything Model 2cited by 154
- 2023On the Challenges and Perspectives of Foundation Models for Medical Image Analysiscited by 135
- 20202018 Robotic Scene Segmentation Challengecited by 124
- 2024BiomedParse: a biomedical foundation model for image parsing of everything everywhere all at oncecited by 111
- 2023SegVol: Universal and Interactive Volumetric Medical Image Segmentationcited by 87
- 2022Video Polyp Segmentation: A Deep Learning Perspectivecited by 82
- 2023MA-SAM: Modality-agnostic SAM Adaptation for 3D Medical Image Segmentationcited by 82
- 20233DSAM-adapter: Holistic adaptation of SAM from 2D to 3D for promptable tumor segmentationcited by 70
- 2024EVF-SAM: Early Vision-Language Fusion for Text-Prompted Segment Anything Modelcited by 65
- 2023Large-Vocabulary Segmentation for Medical Images with Text Promptscited by 62
- 2020Towards Data-Efficient Learning: A Benchmark for COVID-19 CT Lung and Infection Segmentationcited by 53
- 2023The Multi-modality Cell Segmentation Challenge: Towards Universal Solutionscited by 39
- 2024Segment anything model 2: an application to 2D and 3D medical imagescited by 28
- 2024Interactive 3D Medical Image Segmentation with SAM 2cited by 17
- 2024SAM-Med3D-MoE: Towards a Non-Forgetting Segment Anything Model via Mixture of Experts for 3D Medical Image Segmentationcited by 12
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Citing papers per year: 2024: 13; 2025: 20; 2026: 9.
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- 2025MedSAM2: Segment Anything in 3D Medical Images and Videoscited by 96
- 2024SAM2-Adapter: Evaluating & Adapting Segment Anything 2 in Downstream Tasks: Camouflage, Shadow, Medical Image Segmentation, and Morecited by 60
- 2024Unleashing the Potential of SAM2 for Biomedical Images and Videos: A Surveycited by 14
- 2025SAM2 for Image and Video Segmentation: A Comprehensive Surveycited by 13
- 2024When SAM2 Meets Video Camouflaged Object Segmentation: A Comprehensive Evaluation and Adaptationcited by 11
- 2025SegAnyPET: Universal Promptable Segmentation from Positron Emission Tomography Imagescited by 11
- 2025Adapting Vision Foundation Models for Real-time Ultrasound Image Segmentationcited by 9
- 2024Polyp SAM 2: Advancing Zero shot Polyp Segmentation in Colorectal Cancer Detectioncited by 8
- 2025Surgical Scene Understanding in the Era of Foundation AI Models: A Comprehensive Reviewcited by 8
- 2024RevSAM2: Prompt SAM2 for Medical Image Segmentation via Reverse-Propagation without Fine-tuningcited by 7
- 2025SAM3-Adapter: Efficient Adaptation of Segment Anything 3 for Camouflage Object Segmentation, Shadow Detection, and Medical Image Segmentationcited by 7
- 2025MedicoSAM: Robust Improvement of SAM for Medical Imagingcited by 6
30 more
- 2024A Short Review and Evaluation of SAM2's Performance in 3D CT Image Segmentationcited by 5
- 2024Evaluation Study on SAM 2 for Class-agnostic Instance-level Segmentationcited by 5
- 2025Can Foundation Models Really Segment Tumors? A Benchmarking Odyssey in Lung CT Imagingcited by 5
- 2026MedVL-SAM2: A unified 3D medical vision-language model for multimodal reasoning and prompt-driven segmentationcited by 5
- 2024Path-SAM2: Transfer SAM2 for digital pathology semantic segmentationcited by 4
- 2024DRL-STNet: Unsupervised Domain Adaptation for Cross-modality Medical Image Segmentation via Disentangled Representation Learningcited by 3
- 2025Agglomerating Large Vision Encoders via Distillation for VFSS Segmentationcited by 3
- 2025Auto-nnU-Net: Towards Automated Medical Image Segmentationcited by 3
- 2024SAM-Swin: SAM-Driven Dual-Swin Transformers with Adaptive Lesion Enhancement for Laryngo-Pharyngeal Tumor Detectioncited by 2
- 2025Promptable cancer segmentation using minimal expert-curated datacited by 2
- 2025Comparing SAM 2 and SAM 3 for Zero-Shot Segmentation of 3D Medical Datacited by 2
- 2024Adaptive Interactive Segmentation for Multimodal Medical Imaging via Selection Enginecited by 1
- 2024First-frame Supervised Video Polyp Segmentation via Propagative and Semantic Dual-teacher Networkcited by 1
- 2025SAM2-SGP: Enhancing SAM2 for Medical Image Segmentation via Support-Set Guided Promptingcited by 1
- 2025Segment Anything for Cell Trackingcited by 1
- 2026SurgNavAR: An Augmented Reality Surgical Navigation Framework for Optical See-Through Head Mounted Displayscited by 1
- 2024Zero-shot 3D Segmentation of Abdominal Organs in CT Scans Using Segment Anything Model 2: Adapting Video Tracking Capabilities for 3D Medical Imagingcited by 0
- 2025AI-Driven MRI-based Brain Tumour Segmentation Benchmarkingcited by 0
- 2025FreeVPS: Repurposing Training-Free SAM2 for Generalizable Video Polyp Segmentationcited by 0
- 2025Organoid Tracker: A SAM2-Powered Platform for Zero-shot Cyst Analysis in Human Kidney Organoid Videoscited by 0
- 2025EMeRALDS: Electronic Medical Record Driven Automated Lung Nodule Detection and Classification in Thoracic CT Imagescited by 0
- 2025Towards Better Ultrasound Video Segmentation Foundation Model: An Empirical study on SAM2 Finetuning from Data Perspectivecited by 0
- 2025Boundary-Aware Test-Time Adaptation for Zero-Shot Medical Image Segmentationcited by 0
- 2026Sub-Region-Aware Modality Fusion and Adaptive Prompting for Multi-Modal Brain Tumor Segmentationcited by 0
- 2026A Hybrid Mamba-SAM Architecture for Efficient 3D Medical Image Segmentationcited by 0
- 2026Enhancing MedSAM with a Lightweight Box Predictor for Medical Image Segmentationcited by 0
- 2026SAMRI-3D: Adapting SAM2 for 3D MRI Segmentation with Global Volume Tokenscited by 0
- 2026Report Supervisioncited by 0
- 2026LeCor: Learning to Be Corrected by Meta-Learned Test-Time Training for Interactive 3D Lung-Tumour Segmentationcited by 0
- 2026IMVS: Interactive Medical Volume Segmentation with Test-Time Adaptation - A New Method for Annotating Radiology Datasetscited by 0
- 2026IMVS: Interactive Medical Volume Segmentation with Test-Time Adaptation - A New Method for Annotating Radiology Datasets15 Sep 2026
- 2026LeCor: Learning to Be Corrected by Meta-Learned Test-Time Training for Interactive 3D Lung-Tumour Segmentation8 Sep 2026
- 2026Report Supervision27 Aug 2026
- 2026SAMRI-3D: Adapting SAM2 for 3D MRI Segmentation with Global Volume Tokens20 Jul 2026
- 2026Enhancing MedSAM with a Lightweight Box Predictor for Medical Image Segmentation3 Jun 2026
- 2026SurgNavAR: An Augmented Reality Surgical Navigation Framework for Optical See-Through Head Mounted Displays31 Mar 2026
- 2026A Hybrid Mamba-SAM Architecture for Efficient 3D Medical Image Segmentation31 Jan 2026
- 2026Sub-Region-Aware Modality Fusion and Adaptive Prompting for Multi-Modal Brain Tumor Segmentation22 Jan 2026
- 2026MedVL-SAM2: A unified 3D medical vision-language model for multimodal reasoning and prompt-driven segmentation14 Jan 2026
- 2025Boundary-Aware Test-Time Adaptation for Zero-Shot Medical Image Segmentation4 Dec 2025
- 2025Comparing SAM 2 and SAM 3 for Zero-Shot Segmentation of 3D Medical Data26 Nov 2025
- 2025SAM3-Adapter: Efficient Adaptation of Segment Anything 3 for Camouflage Object Segmentation, Shadow Detection, and Medical Image Segmentation24 Nov 2025
30 more
- 2025Towards Better Ultrasound Video Segmentation Foundation Model: An Empirical study on SAM2 Finetuning from Data Perspective7 Nov 2025
- 2025EMeRALDS: Electronic Medical Record Driven Automated Lung Nodule Detection and Classification in Thoracic CT Images15 Sep 2025
- 2025Organoid Tracker: A SAM2-Powered Platform for Zero-shot Cyst Analysis in Human Kidney Organoid Videos14 Sep 2025
- 2025Segment Anything for Cell Tracking12 Sep 2025
- 2025FreeVPS: Repurposing Training-Free SAM2 for Generalizable Video Polyp Segmentation27 Aug 2025
- 2025AI-Driven MRI-based Brain Tumour Segmentation Benchmarking25 Jun 2025
- 2025SAM2-SGP: Enhancing SAM2 for Medical Image Segmentation via Support-Set Guided Prompting24 Jun 2025
- 2025Promptable cancer segmentation using minimal expert-curated data23 May 2025
- 2025Auto-nnU-Net: Towards Automated Medical Image Segmentation22 May 2025
- 2025Can Foundation Models Really Segment Tumors? A Benchmarking Odyssey in Lung CT Imaging2 May 2025
- 2025MedSAM2: Segment Anything in 3D Medical Images and Videos4 Apr 2025
- 2025Agglomerating Large Vision Encoders via Distillation for VFSS Segmentation3 Apr 2025
- 2025Adapting Vision Foundation Models for Real-time Ultrasound Image Segmentation31 Mar 2025
- 2025SAM2 for Image and Video Segmentation: A Comprehensive Survey17 Mar 2025
- 2025SegAnyPET: Universal Promptable Segmentation from Positron Emission Tomography Images20 Feb 2025
- 2025Surgical Scene Understanding in the Era of Foundation AI Models: A Comprehensive Review16 Feb 2025
- 2025MedicoSAM: Robust Improvement of SAM for Medical Imaging20 Jan 2025
- 2024First-frame Supervised Video Polyp Segmentation via Propagative and Semantic Dual-teacher Network21 Dec 2024
- 2024Adaptive Interactive Segmentation for Multimodal Medical Imaging via Selection Engine29 Nov 2024
- 2024SAM-Swin: SAM-Driven Dual-Swin Transformers with Adaptive Lesion Enhancement for Laryngo-Pharyngeal Tumor Detection29 Oct 2024
- 2024When SAM2 Meets Video Camouflaged Object Segmentation: A Comprehensive Evaluation and Adaptation27 Sep 2024
- 2024DRL-STNet: Unsupervised Domain Adaptation for Cross-modality Medical Image Segmentation via Disentangled Representation Learning26 Sep 2024
- 2024RevSAM2: Prompt SAM2 for Medical Image Segmentation via Reverse-Propagation without Fine-tuning6 Sep 2024
- 2024Evaluation Study on SAM 2 for Class-agnostic Instance-level Segmentation4 Sep 2024
- 2024Unleashing the Potential of SAM2 for Biomedical Images and Videos: A Survey23 Aug 2024
- 2024A Short Review and Evaluation of SAM2's Performance in 3D CT Image Segmentation20 Aug 2024
- 2024Zero-shot 3D Segmentation of Abdominal Organs in CT Scans Using Segment Anything Model 2: Adapting Video Tracking Capabilities for 3D Medical Imaging12 Aug 2024
- 2024Polyp SAM 2: Advancing Zero shot Polyp Segmentation in Colorectal Cancer Detection12 Aug 2024
- 2024SAM2-Adapter: Evaluating & Adapting Segment Anything 2 in Downstream Tasks: Camouflage, Shadow, Medical Image Segmentation, and More8 Aug 2024
- 2024Path-SAM2: Transfer SAM2 for digital pathology semantic segmentation7 Aug 2024
- 2025MedSAM2: Segment Anything in 3D Medical Images and Videoscited by 96
- 2024SAM2-Adapter: Evaluating & Adapting Segment Anything 2 in Downstream Tasks: Camouflage, Shadow, Medical Image Segmentation, and Morecited by 60
- 2024Unleashing the Potential of SAM2 for Biomedical Images and Videos: A Surveycited by 14
- 2025SAM2 for Image and Video Segmentation: A Comprehensive Surveycited by 13
- 2024When SAM2 Meets Video Camouflaged Object Segmentation: A Comprehensive Evaluation and Adaptationcited by 11
- 2025SegAnyPET: Universal Promptable Segmentation from Positron Emission Tomography Imagescited by 11
- 2025Adapting Vision Foundation Models for Real-time Ultrasound Image Segmentationcited by 9
- 2024Polyp SAM 2: Advancing Zero shot Polyp Segmentation in Colorectal Cancer Detectioncited by 8
- 2025Surgical Scene Understanding in the Era of Foundation AI Models: A Comprehensive Reviewcited by 8
- 2024RevSAM2: Prompt SAM2 for Medical Image Segmentation via Reverse-Propagation without Fine-tuningcited by 7
- 2025SAM3-Adapter: Efficient Adaptation of Segment Anything 3 for Camouflage Object Segmentation, Shadow Detection, and Medical Image Segmentationcited by 7
- 2025MedicoSAM: Robust Improvement of SAM for Medical Imagingcited by 6
12 most cited of 40 All 40 (JSON)
- 2026IMVS: Interactive Medical Volume Segmentation with Test-Time Adaptation - A New Method for Annotating Radiology Datasets15 Sep 2026
- 2026LeCor: Learning to Be Corrected by Meta-Learned Test-Time Training for Interactive 3D Lung-Tumour Segmentation8 Sep 2026
- 2026Report Supervision27 Aug 2026
- 2026SAMRI-3D: Adapting SAM2 for 3D MRI Segmentation with Global Volume Tokens20 Jul 2026
- 2026Enhancing MedSAM with a Lightweight Box Predictor for Medical Image Segmentation3 Jun 2026
- 2026SurgNavAR: An Augmented Reality Surgical Navigation Framework for Optical See-Through Head Mounted Displays31 Mar 2026
- 2026Sub-Region-Aware Modality Fusion and Adaptive Prompting for Multi-Modal Brain Tumor Segmentation22 Jan 2026
- 2025Boundary-Aware Test-Time Adaptation for Zero-Shot Medical Image Segmentation4 Dec 2025
- 2025Comparing SAM 2 and SAM 3 for Zero-Shot Segmentation of 3D Medical Data26 Nov 2025
- 2025SAM3-Adapter: Efficient Adaptation of Segment Anything 3 for Camouflage Object Segmentation, Shadow Detection, and Medical Image Segmentation24 Nov 2025
- 2025Towards Better Ultrasound Video Segmentation Foundation Model: An Empirical study on SAM2 Finetuning from Data Perspective7 Nov 2025
- 2025EMeRALDS: Electronic Medical Record Driven Automated Lung Nodule Detection and Classification in Thoracic CT Images15 Sep 2025
12 newest of 40 All 40 (JSON)