MedicoSAM: Robust Improvement of SAM for Medical Imaging
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Abstract (arXiv)
Medical image segmentation is an important analysis task in clinical practice and research. Deep learning has massively advanced the field, but current approaches are mostly based on models trained for a specific task. Training such models or adapting them to a new condition is costly due to the need for (manually) labeled data. The emergence of vision foundation models, especially Segment Anything, offers a path to universal segmentation for medical images, overcoming these issues. Here, we study how to improve Segment Anything for medical images by comparing different finetuning strategies on a large and diverse dataset. We evaluate the finetuned models on a wide range of interactive and (automatic) semantic segmentation tasks. We find that the performance can be clearly improved for interactive segmentation. However, semantic segmentation does not benefit from pretraining on medical images. Our best model, MedicoSAM, is publicly available at https://github.com/computational-cell-analytics/medico-sam. We show that it is compatible with existing tools for data annotation and believe that it will be of great practical value.
Key facts. Cited by 6 papers in the map (data through 7 Oct 2026). Builds on 49 of its 85 references that are in the map. First posted on arXiv 20 Jan 2025.
Builds on
49 of 85 references.
References · 49
- 2017Attention Is All You Needcited by 59,932
- 2021Learning Transferable Visual Models From Natural Language Supervisioncited by 33,456
- 2020Language Models are Few-Shot Learnerscited by 32,199
- 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 29,915
- 2021LoRA: Low-Rank Adaptation of Large Language Modelscited by 14,084
- 2023Segment Anythingcited by 8,158
- 2021Masked Autoencoders Are Scalable Vision Learnerscited by 7,339
- 2024SAM 2: Segment Anything in Images and Videoscited by 2,784
- 2021UNETR: Transformers for 3D Medical Image Segmentationcited by 954
- 2022Swin UNETR: Swin Transformers for Semantic Segmentation of Brain Tumors in MRI Imagescited by 823
- 2019Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)cited by 657
- 2022TotalSegmentator: robust segmentation of 104 anatomical structures in CT imagescited by 597
37 more
- 2023Medical SAM Adapter: Adapting Segment Anything Model for Medical Image Segmentationcited by 485
- 2022MONAI: An open-source framework for deep learning in healthcarecited by 438
- 2022AMOS: A Large-Scale Abdominal Multi-Organ Benchmark for Versatile Medical Image Segmentationcited by 347
- 2023Segment Anything Model for Medical Image Analysis: an Experimental Studycited by 291
- 2023Customized Segment Anything Model for Medical Image Segmentationcited by 277
- 2019Deep Learning for Segmentation using an Open Large-Scale Dataset in 2D Echocardiographycited by 243
- 2024nnU-Net Revisited: A Call for Rigorous Validation in 3D Medical Image Segmentationcited by 235
- 2023CLIP-Driven Universal Model for Organ Segmentation and Tumor Detectioncited by 224
- 2019The state of the art in kidney and kidney tumor segmentation in contrast-enhanced CT imaging: Results of the KiTS19 Challengecited by 188
- 2024Medical SAM 2: Segment medical images as video via Segment Anything Model 2cited by 151
- 2023SAM-Med2Dcited by 123
- 2023Segment Anything Is Not Always Perfect: An Investigation of SAM on Different Real-world Applicationscited by 121
- 2023CellViT: Vision Transformers for Precise Cell Segmentation and Classificationcited by 108
- 2024BiomedParse: a biomedical foundation model for image parsing of everything everywhere all at oncecited by 107
- 2023SurgicalSAM: Efficient Class Promptable Surgical Instrument Segmentationcited by 103
- 2024Segment Anything Model for Medical Image Segmentation: Current Applications and Future Directionscited by 97
- 2023MA-SAM: Modality-agnostic SAM Adaptation for 3D Medical Image Segmentationcited by 82
- 2023Polyp-SAM: Transfer SAM for Polyp Segmentationcited by 64
- 2024SAM2-UNet: Segment Anything 2 Makes Strong Encoder for Natural and Medical Image Segmentationcited by 63
- 2023Large-Vocabulary Segmentation for Medical Images with Text Promptscited by 60
- 2023SA-Med2D-20M Dataset: Segment Anything in 2D Medical Imaging with 20 Million maskscited by 54
- 2024Surgical SAM 2: Real-time Segment Anything in Surgical Video by Efficient Frame Pruningcited by 46
- 2023Computer-Vision Benchmark Segment-Anything Model (SAM) in Medical Images: Accuracy in 12 Datasetscited by 45
- 2024Segment Anything in Medical Images and Videos: Benchmark and Deploymentcited by 42
- 2023Segment Anything Model for Medical Images?cited by 39
- 2024MedCLIP-SAMv2: Towards Universal Text-Driven Medical Image Segmentationcited by 37
- 2023SAM3D: Segment Anything Model in Volumetric Medical Imagescited by 34
- 2024How to build the best medical image segmentation algorithm using foundation models: a comprehensive empirical study with Segment Anything Modelcited by 32
- 2023SAMM (Segment Any Medical Model): A 3D Slicer Integration to SAMcited by 31
- 2023Lumbar spine segmentation in MR images: a dataset and a public benchmarkcited by 30
- 2021Tracked 3D Ultrasound and Deep Neural Network-based Thyroid Segmentation reduce Interobserver Variability in Thyroid Volumetrycited by 29
- 2024Foundation Models for Biomedical Image Segmentation: A Surveycited by 28
- 2024Segment anything model 2: an application to 2D and 3D medical imagescited by 27
- 2020m2caiSeg: Semantic Segmentation of Laparoscopic Images using Convolutional Neural Networkscited by 25
- 2023MicroSegNet: A Deep Learning Approach for Prostate Segmentation on Micro-Ultrasound Imagescited by 25
- 2024MulModSeg: Enhancing Unpaired Multi-Modal Medical Image Segmentation with Modality-Conditioned Text Embedding and Alternating Trainingcited by 6
- 2024SAM-REF: Introducing Image-Prompt Synergy during Interaction for Detail Enhancement in the Segment Anything Modelcited by 2
Built on by
Citing papers per year: 2025: 2; 2026: 4.
6 papers.
- 2025MedSAMix: A Training-Free Model Merging Approach for Medical Image Segmentationcited by 3
- 2026Revisiting foundation models for cell instance segmentationcited by 2
- 2025BALR-SAM: Boundary-Aware Low-Rank Adaptation of SAM for Resource-Efficient Medical Image Segmentationcited by 0
- 2026LUMOS: Latent Universal Medical Priors for Segmentationcited by 0
- 2026μMatch: Foundation Models for Semi-supervised Learning and Domain Adaptation in EMcited by 0
- 2026Vision Foundation Models in Radiology: A Scoping Review of Data, Methodology, Evaluation and Clinical Translationcited by 0
- 2026Vision Foundation Models in Radiology: A Scoping Review of Data, Methodology, Evaluation and Clinical Translation8 Jul 2026
- 2026μMatch: Foundation Models for Semi-supervised Learning and Domain Adaptation in EM19 Jun 2026
- 2026Revisiting foundation models for cell instance segmentation18 Mar 2026
- 2026LUMOS: Latent Universal Medical Priors for Segmentation1 Mar 2026
- 2025BALR-SAM: Boundary-Aware Low-Rank Adaptation of SAM for Resource-Efficient Medical Image Segmentation29 Sep 2025
- 2025MedSAMix: A Training-Free Model Merging Approach for Medical Image Segmentation14 Aug 2025