Towards Data-Efficient Learning: A Benchmark for COVID-19 CT Lung and Infection Segmentation
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Abstract (arXiv)
Purpose: Accurate segmentation of lung and infection in COVID-19 CT scans plays an important role in the quantitative management of patients. Most of the existing studies are based on large and private annotated datasets that are impractical to obtain from a single institution, especially when radiologists are busy fighting the coronavirus disease. Furthermore, it is hard to compare current COVID-19 CT segmentation methods as they are developed on different datasets, trained in different settings, and evaluated with different metrics. Methods: To promote the development of data-efficient deep learning methods, in this paper, we built three benchmarks for lung and infection segmentation based on 70 annotated COVID-19 cases, which contain current active research areas, e.g., few-shot learning, domain generalization, and knowledge transfer. For a fair comparison among different segmentation methods, we also provide standard training, validation and testing splits, evaluation metrics and, the corresponding code. Results: Based on the state-of-the-art network, we provide more than 40 pre-trained baseline models, which not only serve as out-of-the-box segmentation tools but also save computational time for researchers who are interested in COVID-19 lung and infection segmentation. We achieve average Dice Similarity Coefficient (DSC) scores of 97.3%, 97.7%, and 67.3% and average Normalized Surface Dice (NSD) scores of 90.6%, 91.4%, and 70.0% for left lung, right lung, and infection, respectively. Conclusions: To the best of our knowledge, this work presents the first data-efficient learning benchmark for medical image segmentation and the largest number of pre-trained models up to now. All these resources are publicly available, and our work lays the foundation for promoting the development of deep learning methods for efficient COVID-19 CT segmentation with limited data.
Key facts. Cited by 53 papers in the map (data through 7 Oct 2026). First posted on arXiv 27 Apr 2020.
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Citing papers per year: 2021: 10; 2022: 10; 2023: 10; 2024: 7; 2025: 10; 2026: 6.
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- 2022Learning with Limited Annotations: A Survey on Deep Semi-Supervised Learning for Medical Image Segmentationcited by 74
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- 2024Segment Anything in Medical Images and Videos: Benchmark and Deploymentcited by 42
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- 2021Cutting-edge 3D Medical Image Segmentation Methods in 2020: Are Happy Families All Alike?cited by 7
- 2022Boosting COVID-19 Severity Detection with Infection-aware Contrastive Mixup Classificationcited by 7
- 2025Lung-DDPM: Semantic Layout-guided Diffusion Models for Thoracic CT Image Synthesiscited by 7
- 2025STPNet: Scale-aware Text Prompt Network for Medical Image Segmentationcited by 6
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- 2022Deep Learning in Single-Cell Analysiscited by 4
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- 2024LoRKD: Low-Rank Knowledge Decomposition for Medical Foundation Modelscited by 4
- 2025Lung-DDPM+: Efficient Thoracic CT Image Synthesis using Diffusion Probabilistic Modelcited by 4
- 2021Automated lung segmentation from CT images of normal and COVID-19 pneumonia patientscited by 3
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- 2024Shape-aware synthesis of pathological lung CT scans using CycleGAN for enhanced semi-supervised lung segmentationcited by 0
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50 most cited of 53 All 53 (JSON)
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- 2025MedROV: Towards Real-Time Open-Vocabulary Detection Across Diverse Medical Imaging Modalities25 Nov 2025
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- 2025Unmasking Interstitial Lung Diseases: Leveraging Masked Autoencoders for Diagnosis6 Aug 2025
- 2025Is Visual in-Context Learning for Compositional Medical Tasks within Reach?1 Jul 2025
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- 2025M^3Builder: A Multi-Agent System for Automated Machine Learning in Medical Imaging27 Feb 2025
- 2025Lung-DDPM: Semantic Layout-guided Diffusion Models for Thoracic CT Image Synthesis21 Feb 2025
- 2024DB-SAM: Delving into High Quality Universal Medical Image Segmentation5 Oct 2024
- 2024LoRKD: Low-Rank Knowledge Decomposition for Medical Foundation Models29 Sep 2024
- 2024Segment Anything in Medical Images and Videos: Benchmark and Deployment6 Aug 2024
- 2024Shape-aware synthesis of pathological lung CT scans using CycleGAN for enhanced semi-supervised lung segmentation14 May 2024
- 2024SAM3D: Zero-Shot Semi-Automatic Segmentation in 3D Medical Images with the Segment Anything Model10 May 2024
- 2024SAMCT: Segment Any CT Allowing Labor-Free Task-Indicator Prompts20 Mar 2024
- 2024CDSE-UNet: Enhancing COVID-19 CT Image Segmentation with Canny Edge Detection and Dual-Path SENet Feature Fusion3 Mar 2024
- 2023Large-Vocabulary Segmentation for Medical Images with Text Prompts28 Dec 2023
- 2023A Self Supervised StyleGAN for Image Annotation and Classification with Extremely Limited Labels26 Dec 2023
- 2023PnPNet: Pull-and-Push Networks for Volumetric Segmentation with Boundary Confusion13 Dec 2023
- 2023Medical Image Segmentation with Domain Adaptation: A Survey3 Nov 2023
- 2023Attention Mechanisms in Medical Image Segmentation: A Survey29 May 2023
- 2023D-TrAttUnet: Dual-Decoder Transformer-Based Attention Unet Architecture for Binary and Multi-classes Covid-19 Infection Segmentation27 Mar 2023
- 20232D and 3D CNN-Based Fusion Approach for COVID-19 Severity Prediction from 3D CT-Scans15 Mar 2023
- 2023DACov: A Deeper Analysis of Data Augmentation on the Computed Tomography Segmentation Problem10 Mar 2023
- 2023A residual dense vision transformer for medical image super-resolution with segmentation-based perceptual loss fine-tuning22 Feb 2023
- 2023COVID-19 Infection Analysis Framework using Novel Boosted CNNs and Radiological Images6 Feb 2023
- 2022Collective Intelligent Strategy for Improved Segmentation of COVID-19 from CT23 Dec 2022
- 2022Boosting COVID-19 Severity Detection with Infection-aware Contrastive Mixup Classification26 Nov 2022
- 2022Deep Learning in Single-Cell Analysis22 Oct 2022
- 2022COVID-19 Detection and Analysis From Lung CT Images using Novel Channel Boosted CNNs22 Sep 2022
- 2022Learning with Limited Annotations: A Survey on Deep Semi-Supervised Learning for Medical Image Segmentation28 Jul 2022
- 2022Ensemble CNN models for Covid-19 Recognition and Severity Perdition From 3D CT-scan29 Jun 2022
- 2022COVIDx CT-3: A Large-scale, Multinational, Open-Source Benchmark Dataset for Computer-aided COVID-19 Screening from Chest CT Images7 Jun 2022
- 2022Using the Order of Tomographic Slices as a Prior for Neural Networks Pre-Training17 Mar 2022
- 2022A novel unsupervised covid lung lesion segmentation based on the lung tissue identification24 Feb 2022
- 2022Feasibility Study of Multi-Site Split Learning for Privacy-Preserving Medical Systems under Data Imbalance Constraints in COVID-19, X-Ray, and Cholesterol Dataset21 Feb 2022
- 2021Uncertainty-Guided Mutual Consistency Learning for Semi-Supervised Medical Image Segmentation5 Dec 2021
- 2021Diagnosis of COVID-19 Using Machine Learning and Deep Learning: A review28 Oct 2021
- 2021Learning from Pseudo Lesion: A Self-supervised Framework for COVID-19 Diagnosis23 Jun 2021
- 2021KRADA: Known-region-aware Domain Alignment for Open-set Domain Adaptation in Semantic Segmentation11 Jun 2021
- 2021Quantification of pulmonary involvement in COVID-19 pneumonia by means of a cascade oftwo U-nets: training and assessment on multipledatasets using different annotation criteria6 May 2021
- 2021Automated lung segmentation from CT images of normal and COVID-19 pneumonia patients5 Apr 2021
- 20213D U-Net for segmentation of COVID-19 associated pulmonary infiltrates using transfer learning: State-of-the-art results on affordable hardware25 Jan 2021
50 newest of 53 All 53 (JSON)
- 2022Learning with Limited Annotations: A Survey on Deep Semi-Supervised Learning for Medical Image Segmentationcited by 74
- 2023Large-Vocabulary Segmentation for Medical Images with Text Promptscited by 60
- 2024Segment Anything in Medical Images and Videos: Benchmark and Deploymentcited by 42
- 2021COVID-Net CT-2: Enhanced Deep Neural Networks for Detection of COVID-19 from Chest CT Images Through Bigger, More Diverse Learningcited by 29
- 2021Uncertainty-Guided Mutual Consistency Learning for Semi-Supervised Medical Image Segmentationcited by 22
- 2021Automated Model Design and Benchmarking of 3D Deep Learning Models for COVID-19 Detection with Chest CT Scanscited by 13
- 2022COVID-19 Detection and Analysis From Lung CT Images using Novel Channel Boosted CNNscited by 12
- 2023Attention Mechanisms in Medical Image Segmentation: A Surveycited by 9
- 2021Cutting-edge 3D Medical Image Segmentation Methods in 2020: Are Happy Families All Alike?cited by 7
- 2022Boosting COVID-19 Severity Detection with Infection-aware Contrastive Mixup Classificationcited by 7
- 2025STPNet: Scale-aware Text Prompt Network for Medical Image Segmentationcited by 6
- 2021Diagnosis of COVID-19 Using Machine Learning and Deep Learning: A reviewcited by 5
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- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigms29 Jun 2026
- 2026Vision Transformer-Conditioned UNet for Domain-Adaptive Semantic Segmentation12 May 2026
- 2026Probing Intrinsic Medical Task Relationships: A Contrastive Learning Perspective7 Apr 2026
- 2026FALCON: Few-Shot Adversarial Learning for Cross-Domain Medical Image Segmentation4 Jan 2026
- 2025MedROV: Towards Real-Time Open-Vocabulary Detection Across Diverse Medical Imaging Modalities25 Nov 2025
- 2025Lite ENSAM: a lightweight cancer segmentation model for 3D Computed Tomography3 Nov 2025
- 2025Unmasking Interstitial Lung Diseases: Leveraging Masked Autoencoders for Diagnosis6 Aug 2025
- 2025Is Visual in-Context Learning for Compositional Medical Tasks within Reach?1 Jul 2025
- 2025Rethinking Whole-Body CT Image Interpretation: An Abnormality-Centric Approach3 Jun 2025
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- 2025STPNet: Scale-aware Text Prompt Network for Medical Image Segmentation2 Apr 2025
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