MedIAnomaly: A comparative study of anomaly detection in medical images
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Abstract (arXiv)
Anomaly detection (AD) aims at detecting abnormal samples that deviate from the expected normal patterns. Generally, it can be trained merely on normal data, without a requirement for abnormal samples, and thereby plays an important role in rare disease recognition and health screening in the medical domain. Despite the emergence of numerous methods for medical AD, the lack of a fair and comprehensive evaluation causes ambiguous conclusions and hinders the development of this field. To address this problem, this paper builds a benchmark with unified comparison. Seven medical datasets with five image modalities, including chest X-rays, brain MRIs, retinal fundus images, dermatoscopic images, and histopathology images, are curated for extensive evaluation. Thirty typical AD methods, including reconstruction and self-supervised learning-based methods, are involved in comparison of image-level anomaly classification and pixel-level anomaly segmentation. Furthermore, for the first time, we systematically investigate the effect of key components in existing methods, revealing unresolved challenges and potential future directions. The datasets and code are available at https://github.com/caiyu6666/MedIAnomaly.
Key facts. Cited by 25 papers in the map (data through 7 Oct 2026). Builds on 86 of its 119 references that are in the map. First posted on arXiv 6 Apr 2024.
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86 of 119 references.
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50 most cited of 86 All 86 (JSON)
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Citing papers per year: 2024: 3; 2025: 10; 2026: 12.
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- 2024Incomplete Multimodal Industrial Anomaly Detection via Cross-Modal Distillationcited by 6
- 2025Scale-Aware Contrastive Reverse Distillation for Unsupervised Medical Anomaly Detectioncited by 6
- 2024Revisiting Deep Ensemble Uncertainty for Enhanced Medical Anomaly Detectioncited by 4
- 2025A Survey on Video Anomaly Detection via Deep Learning: Human, Vehicle, and Environmentcited by 4
- 2026Dual Distillation for Few-Shot Anomaly Detectioncited by 3
- 2024Evaluating Self-Supervised Learning in Medical Imaging: A Benchmark for Robustness, Generalizability, and Multi-Domain Impactcited by 2
- 2025Q-Former Autoencoder: A Modern Framework for Medical Anomaly Detectioncited by 2
- 2025Quantitative Benchmarking of Anomaly Detection Methods in Digital Pathologycited by 1
- 2025BenchReAD: A systematic benchmark for retinal anomaly detectioncited by 1
- 2025Unsupervised anomaly detection using Bayesian flow networks: application to brain FDG PET in the context of Alzheimer's diseasecited by 1
- 2025OCSVM-Guided Representation Learning for Unsupervised Anomaly Detectioncited by 1
- 2025From Pixels to Graphs: Deep Graph-Level Anomaly Detection on Dermoscopic Imagescited by 1
13 more
- 2025FedDyMem: Efficient Federated Learning with Dynamic Memory and Memory-Reduce for Unsupervised Image Anomaly Detectioncited by 0
- 2025Unsupervised Anomaly Detection in Brain MRI via Disentangled Anatomy Learningcited by 0
- 2026Unsupervised Anomaly Detection of Diseases in the Female Pelvis for Real-Time MR Imagingcited by 0
- 2026PDD: Manifold-Prior Diverse Distillation for Medical Anomaly Detectioncited by 0
- 2026Latent Anomaly Knowledge Excavation: Unveiling Sparse Sensitive Neurons in Vision-Language Modelscited by 0
- 2026Anatomy-Aware Unsupervised Detection and Localization of Retinal Abnormalities in Optical Coherence Tomographycited by 0
- 2026MTL-MAD: Multi-Task Learners are Effective Medical Anomaly Detectorscited by 0
- 2026AUCp: Pseudo-AUC for Inference Model Selection with Unlabeled Validation Data in Abnormality Detectioncited by 0
- 2026HiMatch-AD: DINOv3-driven Hierarchical Matching for Training-free Medical Anomaly Detectioncited by 0
- 2026Super-Generalist: Towards Comprehensive and Accurate Medical Image Understanding via Generalist-Specialist Synergycited by 0
- 2026Memory-Bounded Continuation of Greedy Sampling for Continual Anomaly Detectioncited by 0
- 2026GeoMAD: Geometry-Aware Multi-View Anomaly Detection via Deformable Fusion and Distributional Alignmentcited by 0
- 2026Interpretable Multi-Hypersphere Deep Anomaly Detection for Open-set Supervised Anomaly Detectioncited by 0
- 2026Interpretable Multi-Hypersphere Deep Anomaly Detection for Open-set Supervised Anomaly Detection19 Sep 2026
- 2026GeoMAD: Geometry-Aware Multi-View Anomaly Detection via Deformable Fusion and Distributional Alignment27 Aug 2026
- 2026Memory-Bounded Continuation of Greedy Sampling for Continual Anomaly Detection15 Aug 2026
- 2026Super-Generalist: Towards Comprehensive and Accurate Medical Image Understanding via Generalist-Specialist Synergy10 Jul 2026
- 2026HiMatch-AD: DINOv3-driven Hierarchical Matching for Training-free Medical Anomaly Detection21 Jun 2026
- 2026AUCp: Pseudo-AUC for Inference Model Selection with Unlabeled Validation Data in Abnormality Detection7 Jun 2026
- 2026MTL-MAD: Multi-Task Learners are Effective Medical Anomaly Detectors7 May 2026
- 2026Anatomy-Aware Unsupervised Detection and Localization of Retinal Abnormalities in Optical Coherence Tomography24 Apr 2026
- 2026Latent Anomaly Knowledge Excavation: Unveiling Sparse Sensitive Neurons in Vision-Language Models9 Apr 2026
- 2026PDD: Manifold-Prior Diverse Distillation for Medical Anomaly Detection7 Mar 2026
- 2026Dual Distillation for Few-Shot Anomaly Detection2 Mar 2026
- 2026Unsupervised Anomaly Detection of Diseases in the Female Pelvis for Real-Time MR Imaging5 Feb 2026
13 more
- 2025Unsupervised Anomaly Detection in Brain MRI via Disentangled Anatomy Learning26 Dec 2025
- 2025A Survey on Video Anomaly Detection via Deep Learning: Human, Vehicle, and Environment19 Aug 2025
- 2025From Pixels to Graphs: Deep Graph-Level Anomaly Detection on Dermoscopic Images15 Aug 2025
- 2025OCSVM-Guided Representation Learning for Unsupervised Anomaly Detection25 Jul 2025
- 2025Q-Former Autoencoder: A Modern Framework for Medical Anomaly Detection24 Jul 2025
- 2025Unsupervised anomaly detection using Bayesian flow networks: application to brain FDG PET in the context of Alzheimer's disease23 Jul 2025
- 2025BenchReAD: A systematic benchmark for retinal anomaly detection14 Jul 2025
- 2025Quantitative Benchmarking of Anomaly Detection Methods in Digital Pathology24 Jun 2025
- 2025Scale-Aware Contrastive Reverse Distillation for Unsupervised Medical Anomaly Detection18 Mar 2025
- 2025FedDyMem: Efficient Federated Learning with Dynamic Memory and Memory-Reduce for Unsupervised Image Anomaly Detection28 Feb 2025
- 2024Evaluating Self-Supervised Learning in Medical Imaging: A Benchmark for Robustness, Generalizability, and Multi-Domain Impact26 Dec 2024
- 2024Revisiting Deep Ensemble Uncertainty for Enhanced Medical Anomaly Detection26 Sep 2024
- 2024Incomplete Multimodal Industrial Anomaly Detection via Cross-Modal Distillation22 May 2024
- 2024Incomplete Multimodal Industrial Anomaly Detection via Cross-Modal Distillationcited by 6
- 2025Scale-Aware Contrastive Reverse Distillation for Unsupervised Medical Anomaly Detectioncited by 6
- 2024Revisiting Deep Ensemble Uncertainty for Enhanced Medical Anomaly Detectioncited by 4
- 2025A Survey on Video Anomaly Detection via Deep Learning: Human, Vehicle, and Environmentcited by 4
- 2026Dual Distillation for Few-Shot Anomaly Detectioncited by 3
- 2024Evaluating Self-Supervised Learning in Medical Imaging: A Benchmark for Robustness, Generalizability, and Multi-Domain Impactcited by 2
- 2025Q-Former Autoencoder: A Modern Framework for Medical Anomaly Detectioncited by 2
- 2025Quantitative Benchmarking of Anomaly Detection Methods in Digital Pathologycited by 1
- 2025BenchReAD: A systematic benchmark for retinal anomaly detectioncited by 1
- 2025Unsupervised anomaly detection using Bayesian flow networks: application to brain FDG PET in the context of Alzheimer's diseasecited by 1
- 2025OCSVM-Guided Representation Learning for Unsupervised Anomaly Detectioncited by 1
- 2025From Pixels to Graphs: Deep Graph-Level Anomaly Detection on Dermoscopic Imagescited by 1
12 most cited of 23 All 23 (JSON)
- 2026Interpretable Multi-Hypersphere Deep Anomaly Detection for Open-set Supervised Anomaly Detection19 Sep 2026
- 2026GeoMAD: Geometry-Aware Multi-View Anomaly Detection via Deformable Fusion and Distributional Alignment27 Aug 2026
- 2026Memory-Bounded Continuation of Greedy Sampling for Continual Anomaly Detection15 Aug 2026
- 2026Super-Generalist: Towards Comprehensive and Accurate Medical Image Understanding via Generalist-Specialist Synergy10 Jul 2026
- 2026HiMatch-AD: DINOv3-driven Hierarchical Matching for Training-free Medical Anomaly Detection21 Jun 2026
- 2026AUCp: Pseudo-AUC for Inference Model Selection with Unlabeled Validation Data in Abnormality Detection7 Jun 2026
- 2026Anatomy-Aware Unsupervised Detection and Localization of Retinal Abnormalities in Optical Coherence Tomography24 Apr 2026
- 2026PDD: Manifold-Prior Diverse Distillation for Medical Anomaly Detection7 Mar 2026
- 2026Dual Distillation for Few-Shot Anomaly Detection2 Mar 2026
- 2026Unsupervised Anomaly Detection of Diseases in the Female Pelvis for Real-Time MR Imaging5 Feb 2026
- 2025Unsupervised Anomaly Detection in Brain MRI via Disentangled Anatomy Learning26 Dec 2025
- 2025A Survey on Video Anomaly Detection via Deep Learning: Human, Vehicle, and Environment19 Aug 2025
12 newest of 23 All 23 (JSON)