mlsanityData to 14 Oct 2026

AnnaAgent: Dynamic Evolution Agent System with Multi-Session Memory for Realistic Seeker Simulation

arXiv 2506.00551 ↗First posted 31 May 2025cs.CL cs.AIcited by 21

On the map: LLM agents and tool use → Medical and scientific domain agents

Abstract (arXiv)

Constrained by the cost and ethical concerns of involving real seekers in AI-driven mental health, researchers develop LLM-based conversational agents (CAs) with tailored configurations, such as profiles, symptoms, and scenarios, to simulate seekers. While these efforts advance AI in mental health, achieving more realistic seeker simulation remains hindered by two key challenges: dynamic evolution and multi-session memory. Seekers' mental states often fluctuate during counseling, which typically spans multiple sessions. To address this, we propose AnnaAgent, an emotional and cognitive dynamic agent system equipped with tertiary memory. AnnaAgent incorporates an emotion modulator and a complaint elicitor trained on real counseling dialogues, enabling dynamic control of the simulator's configurations. Additionally, its tertiary memory mechanism effectively integrates short-term and long-term memory across sessions. Evaluation results, both automated and manual, demonstrate that AnnaAgent achieves more realistic seeker simulation in psychological counseling compared to existing baselines. The ethically reviewed and screened code can be found on https://github.com/sci-m-wang/AnnaAgent.

Key facts. Cited by 21 papers in the map (data through 14 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 19 of its 62 references that are in the map. First posted on arXiv 31 May 2025.

Builds on

19 of 62 references.

Closest ancestors · 1

Same direction, newest first

  1. 2024Interactive Agents: Simulating Counselor-Client Psychological Counseling via Role-Playing LLM-to-LLM Interactions28 Aug

Other references · 18

  1. 2019BERTScore: Evaluating Text Generation with BERTcited by 5,512
  2. 2023G-Eval: NLG Evaluation using GPT-4 with Better Human Alignmentcited by 2,276
  3. 2023Baichuan 2: Open Large-scale Language Modelscited by 670
  4. 2020GoEmotions: A Dataset of Fine-Grained Emotionscited by 486
  5. 2025Agentic Retrieval-Augmented Generation: A Survey on Agentic RAGcited by 249
  6. 2024Two Tales of Persona in LLMs: A Survey of Role-Playing and Personalizationcited by 208
  7. 2022The Carbon Footprint of Machine Learning Training Will Plateau, Then Shrinkcited by 184
  8. 2023InCharacter: Evaluating Personality Fidelity in Role-Playing Agents through Psychological Interviewscited by 179
  9. 2023SoulChat: Improving LLMs' Empathy, Listening, and Comfort Abilities through Fine-tuning with Multi-turn Empathy Conversationscited by 110
  10. 2024Large Language Models are Superpositions of All Characters: Attaining Arbitrary Role-play via Self-Alignmentcited by 104
  11. 2024CPsyCoun: A Report-based Multi-turn Dialogue Reconstruction and Evaluation Framework for Chinese Psychological Counselingcited by 89
  12. 2024The Oscars of AI Theater: A Survey on Role-Playing with Language Modelscited by 48
6 more
  1. 2022D4: a Chinese Dialogue Dataset for Depression-Diagnosis-Oriented Chatcited by 37
  2. 2024PsycoLLM: Enhancing LLM for Psychological Understanding and Evaluationcited by 26
  3. 2024Leveraging Large Language Model as Simulated Patients for Clinical Educationcited by 21
  4. 2024Depression Diagnosis Dialogue Simulation: Self-improving Psychiatrist with Tertiary Memorycited by 14
  5. 2023Deep Learning Mental Health Dialogue Systemcited by 9
  6. 2024Minstrel: Structural Prompt Generation with Multi-Agents Coordination for Non-AI Expertscited by 4

Built on by

Cited by year (2026 to 14 Oct)

Citing papers per year: 2025: 2; 2026: 19.

21 papers.

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  1. 2026ES-MemEval: Benchmarking Conversational Agents on Personalized Long-Term Emotional Supportcited by 11
  2. 2026LifeSim: Long-Horizon User Life Simulator for Personalized Assistant Evaluationcited by 11
  3. 2025TheraMind: A Strategic and Adaptive Agent for Longitudinal Psychological Counselingcited by 7
  4. 2026PatientHub: A Unified Framework for Patient Simulationcited by 4
  5. 2026Controlling Long-Horizon Behavior in Language Model Agents with Explicit State Dynamicscited by 3
  6. 2026Responsible Evaluation of AI for Mental Healthcited by 2
  7. 2026Momento: Evaluating Persistent Memory and Reasoning with Multi-Session Agentic Conversationscited by 2
  8. 2026Do AI Personas Grow? Analyzing and Benchmarking Personality Evolution in LLM Agents After Life Eventscited by 2
  9. 2025LLMs vs. Chinese Anime Enthusiasts: A Comparative Study on Emotionally Supportive Role-Playingcited by 1
  10. 2026PsyCLIENT: Client Simulation via Conversational Trajectory Modeling for Trainee Practice and Model Evaluation in Mental Health Counselingcited by 1
  11. 2026Stress-Testing Emotional Support Models: Moving from Homogeneous to Diverse Help Seekerscited by 1
  12. 2026DMT-CBT: Longitudinal Therapeutic State Modeling for CBT Counselingcited by 1
9 more
  1. 2026PatientAct: Theory-Grounded Mental Health Client Simulationcited by 1
  2. 2026Enhancing Mental Health Counseling Support in Bangladesh using Culturally-Grounded Knowledgecited by 0
  3. 2026Cognitive Policy-Driven LLM for Diagnosis and Intervention of Cognitive Distortions in Emotional Support Conversationcited by 0
  4. 2026Trust Stack for Mental Health AI: A Survey of Calibration across Human, Interaction, and AI Layerscited by 0
  5. 2026When Clients Stop Following: A Cognitive Conceptualization Diagram-driven Framework for Strategic Counselingcited by 0
  6. 2026PRISM: Prosody-Integrated Multi-Agent Reasoning Framework for Empathetic Spoken Dialoguecited by 0
  7. 2026From Triggers to Emotions: A CPM-Grounded Appraisal Multi-Agent for Dynamic Emotional Evolution in Persona-Based Dialoguecited by 0
  8. 2026From Pattern Recognizers to Personalized Companions: A Survey of Large Language Models in Mental Healthcited by 0
  9. 2026MACBT: A Multi-Agent Cognitive Behavioral Therapy Decision Support System with Longitudinal Memorycited by 0

Similar, not cited

Close in wording, no citation either way

  1. 2026PsychAgent: An Experience-Driven Lifelong Learning Agent for Self-Evolving Psychological Counselor
  2. 2025Dynamic Affective Memory Management for Personalized LLM Agents
  3. 2026PsychEval: A Multi-Session and Multi-Therapy Benchmark for High-Realism AI Psychological Counselor
  4. 2025ESC-Judge: A Framework for Comparing Emotional Support Conversational Agents
  5. 2026PsychoAgent: An Affect-Sensitive Cognitive Architecture for Conflict-Aware Memory in LLM Agents
  6. 2025Tell Me: An LLM-powered Mental Well-being Assistant with RAG, Synthetic Dialogue Generation, and Agentic Planning
  7. 2025MAGneT: Coordinated Multi-Agent Generation of Synthetic Multi-Turn Mental Health Counseling Sessions
  8. 2025MIND: Towards Immersive Psychological Healing with Multi-agent Inner Dialogue