medigan: a Python library of pretrained generative models for medical image synthesis
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Abstract (arXiv)
Synthetic data generated by generative models can enhance the performance and capabilities of data-hungry deep learning models in medical imaging. However, there is (1) limited availability of (synthetic) datasets and (2) generative models are complex to train, which hinders their adoption in research and clinical applications. To reduce this entry barrier, we propose medigan, a one-stop shop for pretrained generative models implemented as an open-source framework-agnostic Python library. medigan allows researchers and developers to create, increase, and domain-adapt their training data in just a few lines of code. Guided by design decisions based on gathered end-user requirements, we implement medigan based on modular components for generative model (i) execution, (ii) visualisation, (iii) search & ranking, and (iv) contribution. The library's scalability and design is demonstrated by its growing number of integrated and readily-usable pretrained generative models consisting of 21 models utilising 9 different Generative Adversarial Network architectures trained on 11 datasets from 4 domains, namely, mammography, endoscopy, x-ray, and MRI. Furthermore, 3 applications of medigan are analysed in this work, which include (a) enabling community-wide sharing of restricted data, (b) investigating generative model evaluation metrics, and (c) improving clinical downstream tasks. In (b), extending on common medical image synthesis assessment and reporting standards, we show Fr'echet Inception Distance variability based on image normalisation and radiology-specific feature extraction.
Key facts. Cited by 14 papers in the map (data through 14 Oct 2026). Builds on 55 of its 118 references that are in the map. First posted on arXiv 28 Sep 2022.
Builds on
55 of 118 references.
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Citing papers per year: 2023: 4; 2024: 5; 2025: 4; 2026: 1.
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- 2023Feature Extraction for Generative Medical Imaging Evaluation: New Evidence Against an Evolving Trendcited by 24
- 2024Fr'echet Radiomic Distance (FRD): A Versatile Metric for Comparing Medical Imaging Datasetscited by 19
- 2025Metrics that matter: Evaluating image quality metrics for medical image generationcited by 12
- 2024Towards Learning Contrast Kinetics with Multi-Condition Latent Diffusion Modelscited by 11
- 2023Single-Model Attribution of Generative Models Through Final-Layer Inversioncited by 10
- 2023Pre- to Post-Contrast Breast MRI Synthesis for Enhanced Tumour Segmentationcited by 9
- 2024Simulating Dynamic Tumor Contrast Enhancement in Breast MRI using Conditional Generative Adversarial Networkscited by 6
- 2024Enhancing the Utility of Privacy-Preserving Cancer Classification using Synthetic Datacited by 3
- 2023RadImageGAN -- A Multi-modal Dataset-Scale Generative AI for Medical Imagingcited by 2
- 2025Assessing the Distributional Fidelity of Synthetic Chest X-rays using the Embedded Characteristic Scorecited by 1
- 2025Enhanced Generative Model Evaluation with Clipped Density and Coveragecited by 1
- 2024Mitigating annotation shift in cancer classification using single image generative modelscited by 0
- 2026Repurposing Image Diffusion Models for Adversarial Synthetic Structured Data: A Case Study of Ground Truth Drift1 May 2026
- 2025Clinically-guided Data Synthesis for Laryngeal Lesion Detection8 Aug 2025
- 2025Enhanced Generative Model Evaluation with Clipped Density and Coverage2 Jul 2025
- 2025Metrics that matter: Evaluating image quality metrics for medical image generation12 May 2025
- 2025Assessing the Distributional Fidelity of Synthetic Chest X-rays using the Embedded Characteristic Score1 Jan 2025
- 2024Fr'echet Radiomic Distance (FRD): A Versatile Metric for Comparing Medical Imaging Datasets2 Dec 2024
- 2024Simulating Dynamic Tumor Contrast Enhancement in Breast MRI using Conditional Generative Adversarial Networks27 Sep 2024
- 2024Enhancing the Utility of Privacy-Preserving Cancer Classification using Synthetic Data17 Jul 2024
- 2024Mitigating annotation shift in cancer classification using single image generative models30 May 2024
- 2024Towards Learning Contrast Kinetics with Multi-Condition Latent Diffusion Models20 Mar 2024
- 2023RadImageGAN -- A Multi-modal Dataset-Scale Generative AI for Medical Imaging10 Dec 2023
- 2023Feature Extraction for Generative Medical Imaging Evaluation: New Evidence Against an Evolving Trend22 Nov 2023
- 2023Feature Extraction for Generative Medical Imaging Evaluation: New Evidence Against an Evolving Trendcited by 24
- 2024Fr'echet Radiomic Distance (FRD): A Versatile Metric for Comparing Medical Imaging Datasetscited by 19
- 2025Metrics that matter: Evaluating image quality metrics for medical image generationcited by 12
- 2023Single-Model Attribution of Generative Models Through Final-Layer Inversioncited by 10
- 2023Pre- to Post-Contrast Breast MRI Synthesis for Enhanced Tumour Segmentationcited by 9
- 2024Simulating Dynamic Tumor Contrast Enhancement in Breast MRI using Conditional Generative Adversarial Networkscited by 6
- 2024Enhancing the Utility of Privacy-Preserving Cancer Classification using Synthetic Datacited by 3
- 2023RadImageGAN -- A Multi-modal Dataset-Scale Generative AI for Medical Imagingcited by 2
- 2025Assessing the Distributional Fidelity of Synthetic Chest X-rays using the Embedded Characteristic Scorecited by 1
- 2025Enhanced Generative Model Evaluation with Clipped Density and Coveragecited by 1
- 2024Mitigating annotation shift in cancer classification using single image generative modelscited by 0
- 2025Clinically-guided Data Synthesis for Laryngeal Lesion Detectioncited by 0
- 2025Clinically-guided Data Synthesis for Laryngeal Lesion Detection8 Aug 2025
- 2025Enhanced Generative Model Evaluation with Clipped Density and Coverage2 Jul 2025
- 2025Metrics that matter: Evaluating image quality metrics for medical image generation12 May 2025
- 2025Assessing the Distributional Fidelity of Synthetic Chest X-rays using the Embedded Characteristic Score1 Jan 2025
- 2024Fr'echet Radiomic Distance (FRD): A Versatile Metric for Comparing Medical Imaging Datasets2 Dec 2024
- 2024Simulating Dynamic Tumor Contrast Enhancement in Breast MRI using Conditional Generative Adversarial Networks27 Sep 2024
- 2024Enhancing the Utility of Privacy-Preserving Cancer Classification using Synthetic Data17 Jul 2024
- 2024Mitigating annotation shift in cancer classification using single image generative models30 May 2024
- 2023RadImageGAN -- A Multi-modal Dataset-Scale Generative AI for Medical Imaging10 Dec 2023
- 2023Feature Extraction for Generative Medical Imaging Evaluation: New Evidence Against an Evolving Trend22 Nov 2023
- 2023Pre- to Post-Contrast Breast MRI Synthesis for Enhanced Tumour Segmentation17 Nov 2023
- 2023Single-Model Attribution of Generative Models Through Final-Layer Inversion26 May 2023