nnDetection: A Self-configuring Method for Medical Object Detection
Not on the map. Why?
Abstract (arXiv)
Simultaneous localisation and categorization of objects in medical images, also referred to as medical object detection, is of high clinical relevance because diagnostic decisions often depend on rating of objects rather than e.g. pixels. For this task, the cumbersome and iterative process of method configuration constitutes a major research bottleneck. Recently, nnU-Net has tackled this challenge for the task of image segmentation with great success. Following nnU-Net's agenda, in this work we systematize and automate the configuration process for medical object detection. The resulting self-configuring method, nnDetection, adapts itself without any manual intervention to arbitrary medical detection problems while achieving results en par with or superior to the state-of-the-art. We demonstrate the effectiveness of nnDetection on two public benchmarks, ADAM and LUNA16, and propose 11 further medical object detection tasks on public data sets for comprehensive method evaluation. Code is at https://github.com/MIC-DKFZ/nnDetection .
Key facts. Cited by 60 papers in the map (data through 7 Oct 2026). Builds on 14 of its 32 references that are in the map. First posted on arXiv 1 Jun 2021.
Builds on
14 of 32 references.
References · 14
- 2016YOLO9000: Better, Faster, Strongercited by 1,429
- 2019Bridging the Gap Between Anchor-based and Anchor-free Detection via Adaptive Training Sample Selectioncited by 539
- 2019A large annotated medical image dataset for the development and evaluation of segmentation algorithmscited by 371
- 2016Validation, comparison, and combination of algorithms for automatic detection of pulmonary nodules in computed tomography images: the LUNA16 challengecited by 198
- 2019The KiTS19 Challenge Data: 300 Kidney Tumor Cases with Clinical Context, CT Semantic Segmentations, and Surgical Outcomescited by 168
- 2018Why rankings of biomedical image analysis competitions should be interpreted with carecited by 90
- 2014A New 2.5D Representation for Lymph Node Detection using Random Sets of Deep Convolutional Neural Network Observationscited by 56
- 2018Retina U-Net: Embarrassingly Simple Exploitation of Segmentation Supervision for Medical Object Detectioncited by 46
- 2018DeepLung: Deep 3D Dual Path Nets for Automated Pulmonary Nodule Detection and Classificationcited by 36
- 2019Improving RetinaNet for CT Lesion Detection with Dense Masks from Weak RECIST Labelscited by 29
- 2017Accurate Pulmonary Nodule Detection in Computed Tomography Images Using Deep Convolutional Neural Networkscited by 26
- 2018S4ND: Single-Shot Single-Scale Lung Nodule Detectioncited by 4
Built on by
Citing papers per year: 2021: 4; 2022: 11; 2023: 11; 2024: 11; 2025: 13; 2026: 10.
60 papers.
Sort:
By area:
- 2025MedAgent-Pro: Towards Evidence-based Multi-modal Medical Diagnosis via Reasoning Agentic Workflowcited by 71
- 2023The TopCoW Challenge -- Topology-Aware Circle of Willis Segmentation for CT and MR Angiographycited by 48
- 2023CLIP in Medical Imaging: A Surveycited by 40
- 2024MLIP: Enhancing Medical Visual Representation with Divergence Encoder and Knowledge-guided Contrastive Learningcited by 23
- 2022Diffeomorphic Image Registration with Neural Velocity Fieldcited by 20
- 2022SATr: Slice Attention with Transformer for Universal Lesion Detectioncited by 17
- 2022medigan: a Python library of pretrained generative models for medical image synthesiscited by 14
- 2021Annotation-efficient cancer detection with report-guided lesion annotation for deep learning-based prostate cancer detection in bpMRIcited by 11
- 2022Unsupervised Contrastive Learning based Transformer for Lung Nodule Detectioncited by 11
- 2022A Learning-based Framework for Topology-Preserving Segmentation using Quasiconformal Mappingscited by 10
- 2021Fully Automatic Deep Learning Framework for Pancreatic Ductal Adenocarcinoma Detection on Computed Tomographycited by 8
- 2024Longitudinal Segmentation of MS Lesions via Temporal Difference Weightingcited by 8
38 more
- 2022Focused Decoding Enables 3D Anatomical Detection by Transformerscited by 6
- 2023MedYOLO: A Medical Image Object Detection Frameworkcited by 5
- 2022Topology-Preserving Segmentation Network: A Deep Learning Segmentation Framework for Connected Componentcited by 4
- 2023Taming Detection Transformers for Medical Object Detectioncited by 4
- 2023Anatomy-Aware Lymph Node Detection in Chest CT using Implicit Station Stratificationcited by 4
- 2024Voxel Scene Graph for Intracranial Hemorrhagecited by 4
- 2024Building a Synthetic Vascular Model: Evaluation in an Intracranial Aneurysms Detection Scenariocited by 4
- 2023Robust Detection Outcome: A Metric for Pathology Detection in Medical Imagescited by 3
- 2024Effective Lymph Nodes Detection in CT Scans Using Location Debiased Query Selection and Contrastive Query Representation in Transformercited by 3
- 2024CAF-YOLO: A Robust Framework for Multi-Scale Lesion Detection in Biomedical Imagerycited by 3
- 2024Anatomical Positional Embeddingscited by 3
- 2021MixMicrobleedNet: segmentation of cerebral microbleeds using nnU-Netcited by 2
- 2022nnOOD: A Framework for Benchmarking Self-supervised Anomaly Localisation Methodscited by 2
- 2024Detection of Intracranial Hemorrhage for Trauma Patientscited by 2
- 2025Mind the Detail: Uncovering Clinically Relevant Image Details in Accelerated MRI with Semantically Diverse Reconstructionscited by 2
- 2021Evaluating Generic Auto-ML Tools for Computational Pathologycited by 1
- 2022Segmentation-Consistent Probabilistic Lesion Countingcited by 1
- 2022Multi-modal volumetric concept activation to explain detection and classification of metastatic prostate cancer on PSMA-PET/CTcited by 1
- 2022Z-SSMNet: Zonal-aware Self-supervised Mesh Network for Prostate Cancer Detection and Diagnosis with Bi-parametric MRIcited by 1
- 2023Accurate Detection of Mediastinal Lesions with nnDetectioncited by 1
- 2023BugNIST -- a Large Volumetric Dataset for Object Detection under Domain Shiftcited by 1
- 2023nnDetection for Intracranial Aneurysms Detection and Localizationcited by 1
- 2023Seeing Beyond Cancer: Multi-Institutional Validation of Object Localization and 3D Semantic Segmentation using Deep Learning for Breast MRIcited by 1
- 2025A Unified Framework for Foreground and Anonymization Area Segmentation in CT and MRI Datacited by 1
- 2025BrainLesion Suite: A Flexible and User-Friendly Framework for Modular Brain Lesion Image Analysiscited by 1
- 2023Integrating features from lymph node stations for metastatic lymph node detectioncited by 0
- 2024Exploring Optical Flow Inclusion into nnU-Net Framework for Surgical Instrument Segmentationcited by 0
- 2024A vascular synthetic model for improved aneurysm segmentation and detection via Deep Neural Networkscited by 0
- 2024Weakly supervised deep learning model with size constraint for prostate cancer detection in multiparametric MRI and generalization to unseen domainscited by 0
- 2025Anatomically-guided masked autoencoder pre-training for aneurysm detectioncited by 0
- 2025From Slices to Sequences: Autoregressive Tracking Transformer for Cohesive and Consistent 3D Lymph Node Detection in CT Scanscited by 0
- 2025Assessing workflow impact and clinical utility of AI-assisted brain aneurysm detection: a multi-reader studycited by 0
- 2025Two-Steps Neural Networks for an Automated Cerebrovascular Landmark Detectioncited by 0
- 2025Visionerves: Automatic and Reproducible Hybrid AI for Peripheral Nervous System Recognition Applied to Endometriosis Casescited by 0
- 2025Anatomy-Aware Lymphoma Lesion Detection in Whole-Body PET/CTcited by 0
- 2025MTMed3D: A Multi-Task Transformer-Based Model for 3D Medical Imagingcited by 0
- 2025Beyond Size and Growth: Rethinking Lung Cancer Screening with AI Based Nodule Detection and Diagnosiscited by 0
- 2025Rethinking Intracranial Aneurysm Vessel Segmentation: A Perspective from Computational Fluid Dynamics Applicationscited by 0
50 most cited of 60 All 60 (JSON)
- 2026Anatomy-Aware Prediction of Bronchoscopic Accessibility from 3D CT29 Sep 2026
- 2026Lesion Detection in CT with Frozen Self-Distilled Features: SALT, a Spatially Adaptive Label-Guided Temperature5 Aug 2026
- 2026LocAnyMed: Vision-Language Grounding for Multimodal Medical Images4 Aug 2026
- 2026RadYOLO: Computationally Efficient 3D Object Detection and Segmentation in CT and MRI1 Aug 2026
- 2026Segmentation, Detection and Explanation: A Unified Framework for CT Appearance Reasoning15 May 2026
- 2026BifDet: A 3D Bifurcation Detection Dataset for Airway-Tree Modeling27 Apr 2026
- 2026Unsupervised Adaptation from FDG to PSMA PET/CT for 3D Lesion Detection under Label Shift14 Mar 2026
- 2026Tri-Reader: An Open-Access, Multi-Stage AI Pipeline for First-Pass Lung Nodule Annotation in Screening CT27 Jan 2026
- 2026Region of interest detection for efficient aortic segmentation13 Jan 2026
- 2026Kidney Cancer Detection Using 3D-Based Latent Diffusion Models9 Jan 2026
- 2025Rethinking Intracranial Aneurysm Vessel Segmentation: A Perspective from Computational Fluid Dynamics Applications1 Dec 2025
- 2025Beyond Size and Growth: Rethinking Lung Cancer Screening with AI Based Nodule Detection and Diagnosis29 Nov 2025
38 more
- 2025MTMed3D: A Multi-Task Transformer-Based Model for 3D Medical Imaging15 Nov 2025
- 2025Anatomy-Aware Lymphoma Lesion Detection in Whole-Body PET/CT10 Nov 2025
- 2025Visionerves: Automatic and Reproducible Hybrid AI for Peripheral Nervous System Recognition Applied to Endometriosis Cases18 Sep 2025
- 2025BrainLesion Suite: A Flexible and User-Friendly Framework for Modular Brain Lesion Image Analysis11 Jul 2025
- 2025Two-Steps Neural Networks for an Automated Cerebrovascular Landmark Detection3 Jul 2025
- 2025Mind the Detail: Uncovering Clinically Relevant Image Details in Accelerated MRI with Semantically Diverse Reconstructions1 Jul 2025
- 2025Assessing workflow impact and clinical utility of AI-assisted brain aneurysm detection: a multi-reader study22 Mar 2025
- 2025MedAgent-Pro: Towards Evidence-based Multi-modal Medical Diagnosis via Reasoning Agentic Workflow21 Mar 2025
- 2025From Slices to Sequences: Autoregressive Tracking Transformer for Cohesive and Consistent 3D Lymph Node Detection in CT Scans11 Mar 2025
- 2025Anatomically-guided masked autoencoder pre-training for aneurysm detection28 Feb 2025
- 2025A Unified Framework for Foreground and Anonymization Area Segmentation in CT and MRI Data8 Jan 2025
- 2024Building a Synthetic Vascular Model: Evaluation in an Intracranial Aneurysms Detection Scenario4 Nov 2024
- 2024Weakly supervised deep learning model with size constraint for prostate cancer detection in multiparametric MRI and generalization to unseen domains4 Nov 2024
- 2024Longitudinal Segmentation of MS Lesions via Temporal Difference Weighting20 Sep 2024
- 2024Anatomical Positional Embeddings16 Sep 2024
- 2024Detection of Intracranial Hemorrhage for Trauma Patients20 Aug 2024
- 2024CAF-YOLO: A Robust Framework for Multi-Scale Lesion Detection in Biomedical Imagery4 Aug 2024
- 2024Voxel Scene Graph for Intracranial Hemorrhage31 Jul 2024
- 2024Effective Lymph Nodes Detection in CT Scans Using Location Debiased Query Selection and Contrastive Query Representation in Transformer4 Apr 2024
- 2024A vascular synthetic model for improved aneurysm segmentation and detection via Deep Neural Networks27 Mar 2024
- 2024Exploring Optical Flow Inclusion into nnU-Net Framework for Surgical Instrument Segmentation15 Mar 2024
- 2024MLIP: Enhancing Medical Visual Representation with Divergence Encoder and Knowledge-guided Contrastive Learning3 Feb 2024
- 2023The TopCoW Challenge -- Topology-Aware Circle of Willis Segmentation for CT and MR Angiography29 Dec 2023
- 2023MedYOLO: A Medical Image Object Detection Framework12 Dec 2023
- 2023CLIP in Medical Imaging: A Survey12 Dec 2023
- 2023Seeing Beyond Cancer: Multi-Institutional Validation of Object Localization and 3D Semantic Segmentation using Deep Learning for Breast MRI27 Nov 2023
- 2023Anatomy-Aware Lymph Node Detection in Chest CT using Implicit Station Stratification28 Jul 2023
- 2023Taming Detection Transformers for Medical Object Detection27 Jun 2023
- 2023nnDetection for Intracranial Aneurysms Detection and Localization22 May 2023
- 2023BugNIST -- a Large Volumetric Dataset for Object Detection under Domain Shift4 Apr 2023
- 2023Accurate Detection of Mediastinal Lesions with nnDetection20 Mar 2023
- 2023Robust Detection Outcome: A Metric for Pathology Detection in Medical Images3 Mar 2023
- 2023Integrating features from lymph node stations for metastatic lymph node detection9 Jan 2023
- 2022Z-SSMNet: Zonal-aware Self-supervised Mesh Network for Prostate Cancer Detection and Diagnosis with Bi-parametric MRI12 Dec 2022
- 2022A Learning-based Framework for Topology-Preserving Segmentation using Quasiconformal Mappings7 Oct 2022
- 2022medigan: a Python library of pretrained generative models for medical image synthesis28 Sep 2022
- 2022nnOOD: A Framework for Benchmarking Self-supervised Anomaly Localisation Methods2 Sep 2022
- 2022Multi-modal volumetric concept activation to explain detection and classification of metastatic prostate cancer on PSMA-PET/CT4 Aug 2022
50 newest of 60 All 60 (JSON)
- 2023The TopCoW Challenge -- Topology-Aware Circle of Willis Segmentation for CT and MR Angiographycited by 48
- 2023CLIP in Medical Imaging: A Surveycited by 40
- 2024MLIP: Enhancing Medical Visual Representation with Divergence Encoder and Knowledge-guided Contrastive Learningcited by 23
- 2022Diffeomorphic Image Registration with Neural Velocity Fieldcited by 20
- 2022SATr: Slice Attention with Transformer for Universal Lesion Detectioncited by 17
- 2022medigan: a Python library of pretrained generative models for medical image synthesiscited by 14
- 2021Annotation-efficient cancer detection with report-guided lesion annotation for deep learning-based prostate cancer detection in bpMRIcited by 11
- 2022Unsupervised Contrastive Learning based Transformer for Lung Nodule Detectioncited by 11
- 2022A Learning-based Framework for Topology-Preserving Segmentation using Quasiconformal Mappingscited by 10
- 2021Fully Automatic Deep Learning Framework for Pancreatic Ductal Adenocarcinoma Detection on Computed Tomographycited by 8
- 2024Longitudinal Segmentation of MS Lesions via Temporal Difference Weightingcited by 8
- 2022Focused Decoding Enables 3D Anatomical Detection by Transformerscited by 6
12 most cited of 57 All 57 (JSON)
- 2026Anatomy-Aware Prediction of Bronchoscopic Accessibility from 3D CT29 Sep 2026
- 2026Lesion Detection in CT with Frozen Self-Distilled Features: SALT, a Spatially Adaptive Label-Guided Temperature5 Aug 2026
- 2026LocAnyMed: Vision-Language Grounding for Multimodal Medical Images4 Aug 2026
- 2026RadYOLO: Computationally Efficient 3D Object Detection and Segmentation in CT and MRI1 Aug 2026
- 2026BifDet: A 3D Bifurcation Detection Dataset for Airway-Tree Modeling27 Apr 2026
- 2026Unsupervised Adaptation from FDG to PSMA PET/CT for 3D Lesion Detection under Label Shift14 Mar 2026
- 2026Tri-Reader: An Open-Access, Multi-Stage AI Pipeline for First-Pass Lung Nodule Annotation in Screening CT27 Jan 2026
- 2026Region of interest detection for efficient aortic segmentation13 Jan 2026
- 2025Rethinking Intracranial Aneurysm Vessel Segmentation: A Perspective from Computational Fluid Dynamics Applications1 Dec 2025
- 2025Beyond Size and Growth: Rethinking Lung Cancer Screening with AI Based Nodule Detection and Diagnosis29 Nov 2025
- 2025MTMed3D: A Multi-Task Transformer-Based Model for 3D Medical Imaging15 Nov 2025
- 2025Anatomy-Aware Lymphoma Lesion Detection in Whole-Body PET/CT10 Nov 2025
12 newest of 57 All 57 (JSON)