NiftyNet: a deep-learning platform for medical imaging
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Abstract (arXiv)
Medical image analysis and computer-assisted intervention problems are increasingly being addressed with deep-learning-based solutions. Established deep-learning platforms are flexible but do not provide specific functionality for medical image analysis and adapting them for this application requires substantial implementation effort. Thus, there has been substantial duplication of effort and incompatible infrastructure developed across many research groups. This work presents the open-source NiftyNet platform for deep learning in medical imaging. The ambition of NiftyNet is to accelerate and simplify the development of these solutions, and to provide a common mechanism for disseminating research outputs for the community to use, adapt and build upon. NiftyNet provides a modular deep-learning pipeline for a range of medical imaging applications including segmentation, regression, image generation and representation learning applications. Components of the NiftyNet pipeline including data loading, data augmentation, network architectures, loss functions and evaluation metrics are tailored to, and take advantage of, the idiosyncracies of medical image analysis and computer-assisted intervention. NiftyNet is built on TensorFlow and supports TensorBoard visualization of 2D and 3D images and computational graphs by default. We present 3 illustrative medical image analysis applications built using NiftyNet: (1) segmentation of multiple abdominal organs from computed tomography; (2) image regression to predict computed tomography attenuation maps from brain magnetic resonance images; and (3) generation of simulated ultrasound images for specified anatomical poses. NiftyNet enables researchers to rapidly develop and distribute deep learning solutions for segmentation, regression, image generation and representation learning applications, or extend the platform to new applications.
Key facts. Cited by 45 papers in the map (data through 7 Oct 2026). First posted on arXiv 11 Sep 2017.
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Citing papers per year: 2021: 13; 2022: 15; 2023: 6; 2024: 4; 2025: 3; 2026: 4.
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- 2022MONAI: An open-source framework for deep learning in healthcarecited by 438
- 2022Transformers in Medical Imaging: A Surveycited by 245
- 2021Recent advances and clinical applications of deep learning in medical image analysiscited by 104
- 2021Transferable Visual Words: Exploiting the Semantics of Anatomical Patterns for Self-supervised Learningcited by 68
- 2023LVM-Med: Learning Large-Scale Self-Supervised Vision Models for Medical Imaging via Second-order Graph Matchingcited by 60
- 2021GaNDLF: A Generally Nuanced Deep Learning Framework for Scalable End-to-End Clinical Workflows in Medical Imagingcited by 25
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- 2021Medical Transformer: Universal Brain Encoder for 3D MRI Analysiscited by 16
- 2022Joint Self-Supervised Image-Volume Representation Learning with Intra-Inter Contrastive Clusteringcited by 16
- 2022PyMIC: A deep learning toolkit for annotation-efficient medical image segmentationcited by 14
- 2022medigan: a Python library of pretrained generative models for medical image synthesiscited by 14
- 2024SegmentAnyBone: A Universal Model that Segments Any Bone at Any Location on MRIcited by 14
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- 2021Automated liver tissues delineation techniques: A systematic survey on machine learning current trends and future orientationscited by 3
- 2021Estimating MRI Image Quality via Image Reconstruction Uncertaintycited by 3
- 2021A Decoupled Uncertainty Model for MRI Segmentation Quality Estimationcited by 3
- 2022Advancing 3D Medical Image Analysis with Variable Dimension Transform based Supervised 3D Pre-trainingcited by 3
- 2022Augmentation based unsupervised domain adaptationcited by 3
- 2022Integrative Imaging Informatics for Cancer Research: Workflow Automation for Neuro-oncology (I3CR-WANO)cited by 3
- 2025KonfAI: A Modular and Fully Configurable Framework for Deep Learning in Medical Imagingcited by 3
- 2021Artificial Intelligence in Tumor Subregion Analysis Based on Medical Imaging: A Reviewcited by 2
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- 2023Kidney abnormality segmentation in thorax-abdomen CT scanscited by 2
- 2026MIP Candy: A Modular PyTorch Framework for Medical Image Processingcited by 2
- 2021MRI Images, Brain Lesions and Deep Learningcited by 1
- 2022An overview of open source Deep Learning-based libraries for Neurosciencecited by 1
- 2023Regional Deep Atrophy: a Self-Supervised Learning Method to Automatically Identify Regions Associated With Alzheimer's Disease Progression From Longitudinal MRIcited by 1
- 2023Seeing Beyond Cancer: Multi-Institutional Validation of Object Localization and 3D Semantic Segmentation using Deep Learning for Breast MRIcited by 1
- 2024DeepGleason: a System for Automated Gleason Grading of Prostate Cancer using Deep Neural Networkscited by 1
- 2024ATOMMIC: An Advanced Toolbox for Multitask Medical Imaging Consistency to facilitate Artificial Intelligence applications from acquisition to analysis in Magnetic Resonance Imagingcited by 1
- 2025Integration of nested cross-validation, automated hyperparameter optimization, high-performance computing to reduce and quantify the variance of test performance estimation of deep learning modelscited by 1
- 2025Deep Learning-Based Automated Workflow for Accurate Segmentation and Measurement of Abdominal Organs in CT Scanscited by 1
- 2021spectrai: A deep learning framework for spectral datacited by 0
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- 2022A novel unsupervised covid lung lesion segmentation based on the lung tissue identificationcited by 0
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- 2022Exploration of Various Deep Learning Models for Increased Accuracy in Automatic Polyp Detectioncited by 0
- 2022Ensemble uncertainty as a criterion for dataset expansion in distinct bone segmentation from upper-body CT imagescited by 0
- 2023Fusing Structural and Functional Connectivities using Disentangled VAE for Detecting MCIcited by 0
- 2026ViX-Ray: A Vietnamese Chest X-Ray Dataset for Vision-Language Modelscited by 0
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- 2026GazeRefine: Expert Gaze as a Test-Time Prompt for Training-Free Medical Image Segmentationcited by 0
- 2026GazeRefine: Expert Gaze as a Test-Time Prompt for Training-Free Medical Image Segmentation1 Sep 2026
- 2026MS-DKC: A Dataset Knowledge Card Framework for Designing and Adapting Medical Image Segmentation Models4 Jun 2026
- 2026ViX-Ray: A Vietnamese Chest X-Ray Dataset for Vision-Language Models16 Mar 2026
- 2026MIP Candy: A Modular PyTorch Framework for Medical Image Processing24 Feb 2026
- 2025KonfAI: A Modular and Fully Configurable Framework for Deep Learning in Medical Imaging13 Aug 2025
- 2025Deep Learning-Based Automated Workflow for Accurate Segmentation and Measurement of Abdominal Organs in CT Scans13 Mar 2025
- 2025Integration of nested cross-validation, automated hyperparameter optimization, high-performance computing to reduce and quantify the variance of test performance estimation of deep learning models11 Mar 2025
- 2024ATOMMIC: An Advanced Toolbox for Multitask Medical Imaging Consistency to facilitate Artificial Intelligence applications from acquisition to analysis in Magnetic Resonance Imaging30 Apr 2024
- 2024DeepGleason: a System for Automated Gleason Grading of Prostate Cancer using Deep Neural Networks25 Mar 2024
- 2024SegmentAnyBone: A Universal Model that Segments Any Bone at Any Location on MRI23 Jan 2024
- 2024Primitive Geometry Segment Pre-training for 3D Medical Image Segmentation8 Jan 2024
- 2023Seeing Beyond Cancer: Multi-Institutional Validation of Object Localization and 3D Semantic Segmentation using Deep Learning for Breast MRI27 Nov 2023
33 more
- 2023Kidney abnormality segmentation in thorax-abdomen CT scans6 Sep 2023
- 2023LVM-Med: Learning Large-Scale Self-Supervised Vision Models for Medical Imaging via Second-order Graph Matching20 Jun 2023
- 2023Fusing Structural and Functional Connectivities using Disentangled VAE for Detecting MCI16 Jun 2023
- 2023Regional Deep Atrophy: a Self-Supervised Learning Method to Automatically Identify Regions Associated With Alzheimer's Disease Progression From Longitudinal MRI10 Apr 2023
- 2023Video Pretraining Advances 3D Deep Learning on Chest CT Tasks2 Apr 2023
- 2022An overview of open source Deep Learning-based libraries for Neuroscience19 Dec 2022
- 2022Joint Self-Supervised Image-Volume Representation Learning with Intra-Inter Contrastive Clustering4 Dec 2022
- 2022MONAI: An open-source framework for deep learning in healthcare4 Nov 2022
- 2022Integrative Imaging Informatics for Cancer Research: Workflow Automation for Neuro-oncology (I3CR-WANO)6 Oct 2022
- 2022medigan: a Python library of pretrained generative models for medical image synthesis28 Sep 2022
- 2022PyMIC: A deep learning toolkit for annotation-efficient medical image segmentation19 Aug 2022
- 2022Ensemble uncertainty as a criterion for dataset expansion in distinct bone segmentation from upper-body CT images19 Aug 2022
- 2022Joint brain tumor segmentation from multi MR sequences through a deep convolutional neural network7 Mar 2022
- 2022Exploration of Various Deep Learning Models for Increased Accuracy in Automatic Polyp Detection4 Mar 2022
- 2022A novel unsupervised covid lung lesion segmentation based on the lung tissue identification24 Feb 2022
- 2022Augmentation based unsupervised domain adaptation23 Feb 2022
- 2022An overview of deep learning in medical imaging17 Feb 2022
- 2022Transformers in Medical Imaging: A Survey24 Jan 2022
- 2022Advancing 3D Medical Image Analysis with Variable Dimension Transform based Supervised 3D Pre-training5 Jan 2022
- 2022ExAID: A Multimodal Explanation Framework for Computer-Aided Diagnosis of Skin Lesions4 Jan 2022
- 2021Generation of microbial colonies dataset with deep learning style transfer6 Nov 2021
- 2021Interactive Segmentation via Deep Learning and B-Spline Explicit Active Surfaces25 Oct 2021
- 2021A Decoupled Uncertainty Model for MRI Segmentation Quality Estimation6 Sep 2021
- 2021spectrai: A deep learning framework for spectral data17 Aug 2021
- 2021Estimating MRI Image Quality via Image Reconstruction Uncertainty21 Jun 2021
- 2021Recent advances and clinical applications of deep learning in medical image analysis27 May 2021
- 2021Medical Transformer: Universal Brain Encoder for 3D MRI Analysis28 Apr 2021
- 2021Artificial Intelligence in Tumor Subregion Analysis Based on Medical Imaging: A Review25 Mar 2021
- 2021Automated liver tissues delineation techniques: A systematic survey on machine learning current trends and future orientations10 Mar 2021
- 2021GaNDLF: A Generally Nuanced Deep Learning Framework for Scalable End-to-End Clinical Workflows in Medical Imaging26 Feb 2021
- 2021Transferable Visual Words: Exploiting the Semantics of Anatomical Patterns for Self-supervised Learning21 Feb 2021
- 2021Learning Multi-Modal Volumetric Prostate Registration with Weak Inter-Subject Spatial Correspondence9 Feb 2021
- 2021MRI Images, Brain Lesions and Deep Learning13 Jan 2021
- 2022MONAI: An open-source framework for deep learning in healthcarecited by 438
- 2022Transformers in Medical Imaging: A Surveycited by 245
- 2021Recent advances and clinical applications of deep learning in medical image analysiscited by 104
- 2021Transferable Visual Words: Exploiting the Semantics of Anatomical Patterns for Self-supervised Learningcited by 68
- 2021GaNDLF: A Generally Nuanced Deep Learning Framework for Scalable End-to-End Clinical Workflows in Medical Imagingcited by 25
- 2022ExAID: A Multimodal Explanation Framework for Computer-Aided Diagnosis of Skin Lesionscited by 19
- 2021Medical Transformer: Universal Brain Encoder for 3D MRI Analysiscited by 16
- 2022Joint Self-Supervised Image-Volume Representation Learning with Intra-Inter Contrastive Clusteringcited by 16
- 2022PyMIC: A deep learning toolkit for annotation-efficient medical image segmentationcited by 14
- 2022medigan: a Python library of pretrained generative models for medical image synthesiscited by 14
- 2024SegmentAnyBone: A Universal Model that Segments Any Bone at Any Location on MRIcited by 14
- 2024Primitive Geometry Segment Pre-training for 3D Medical Image Segmentationcited by 6
12 most cited of 43 All 43 (JSON)
- 2026GazeRefine: Expert Gaze as a Test-Time Prompt for Training-Free Medical Image Segmentation1 Sep 2026
- 2026MS-DKC: A Dataset Knowledge Card Framework for Designing and Adapting Medical Image Segmentation Models4 Jun 2026
- 2026MIP Candy: A Modular PyTorch Framework for Medical Image Processing24 Feb 2026
- 2025KonfAI: A Modular and Fully Configurable Framework for Deep Learning in Medical Imaging13 Aug 2025
- 2025Deep Learning-Based Automated Workflow for Accurate Segmentation and Measurement of Abdominal Organs in CT Scans13 Mar 2025
- 2025Integration of nested cross-validation, automated hyperparameter optimization, high-performance computing to reduce and quantify the variance of test performance estimation of deep learning models11 Mar 2025
- 2024ATOMMIC: An Advanced Toolbox for Multitask Medical Imaging Consistency to facilitate Artificial Intelligence applications from acquisition to analysis in Magnetic Resonance Imaging30 Apr 2024
- 2024DeepGleason: a System for Automated Gleason Grading of Prostate Cancer using Deep Neural Networks25 Mar 2024
- 2024SegmentAnyBone: A Universal Model that Segments Any Bone at Any Location on MRI23 Jan 2024
- 2024Primitive Geometry Segment Pre-training for 3D Medical Image Segmentation8 Jan 2024
- 2023Seeing Beyond Cancer: Multi-Institutional Validation of Object Localization and 3D Semantic Segmentation using Deep Learning for Breast MRI27 Nov 2023
- 2023Kidney abnormality segmentation in thorax-abdomen CT scans6 Sep 2023
12 newest of 43 All 43 (JSON)