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Recursive Partitioning for Heterogeneous Causal Effects

arXiv 1504.01132 ↗First posted 5 Apr 2015stat.ML econ.EMcited by 254

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Abstract (arXiv)

In this paper we study the problems of estimating heterogeneity in causal effects in experimental or observational studies and conducting inference about the magnitude of the differences in treatment effects across subsets of the population. In applications, our method provides a data-driven approach to determine which subpopulations have large or small treatment effects and to test hypotheses about the differences in these effects. For experiments, our method allows researchers to identify heterogeneity in treatment effects that was not specified in a pre-analysis plan, without concern about invalidating inference due to multiple testing. In most of the literature on supervised machine learning (e.g. regression trees, random forests, LASSO, etc.), the goal is to build a model of the relationship between a unit's attributes and an observed outcome. A prominent role in these methods is played by cross-validation which compares predictions to actual outcomes in test samples, in order to select the level of complexity of the model that provides the best predictive power. Our method is closely related, but it differs in that it is tailored for predicting causal effects of a treatment rather than a unit's outcome. The challenge is that the "ground truth" for a causal effect is not observed for any individual unit: we observe the unit with the treatment, or without the treatment, but not both at the same time. Thus, it is not obvious how to use cross-validation to determine whether a causal effect has been accurately predicted. We propose several novel cross-validation criteria for this problem and demonstrate through simulations the conditions under which they perform better than standard methods for the problem of causal effects. We then apply the method to a large-scale field experiment re-ranking results on a search engine.

Key facts. Cited by 254 papers in the map (data through 7 Oct 2026). First posted on arXiv 5 Apr 2015.

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Citing papers per year: 2021: 31; 2022: 40; 2023: 56; 2024: 49; 2025: 40; 2026: 38.

254 papers.

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  1. 2024Causal machine learning for predicting treatment outcomescited by 73
  2. 2025Do-PFN: In-Context Learning for Causal Effect Estimationcited by 46
  3. 2021Causal Effect Inference for Structured Treatmentscited by 38
  4. 2021A Review of Generalizability and Transportabilitycited by 36
  5. 2021Mixed-Integer Optimization with Constraint Learningcited by 30
  6. 2023In Search of Insights, Not Magic Bullets: Towards Demystification of the Model Selection Dilemma in Heterogeneous Treatment Effect Estimationcited by 29
  7. 2021Causal Decision Making and Causal Effect Estimation Are Not the Same... and Why It Matterscited by 25
  8. 2021SurvITE: Learning Heterogeneous Treatment Effects from Time-to-Event Datacited by 25
  9. 2023Explicit Feature Interaction-aware Uplift Network for Online Marketingcited by 25
  10. 2022Transfer Learning on Heterogeneous Feature Spaces for Treatment Effects Estimationcited by 21
  11. 2022Image-based Treatment Effect Heterogeneitycited by 20
  12. 2022Data-Driven Causal Effect Estimation Based on Graphical Causal Modelling: A Surveycited by 19
38 more
  1. 2022Hierarchical Shrinkage: improving the accuracy and interpretability of tree-based methodscited by 18
  2. 2022Robust and Agnostic Learning of Conditional Distributional Treatment Effectscited by 18
  3. 2022Learning Disentangled Representations for Counterfactual Regression via Mutual Information Minimizationcited by 18
  4. 2023Zero-shot causal learningcited by 17
  5. 2023Causal Inference with Conditional Front-Door Adjustment and Identifiable Variational Autoencodercited by 17
  6. 2023Causal isotonic calibration for heterogeneous treatment effectscited by 16
  7. 2023Off-Policy Evaluation of Ranking Policies under Diverse User Behaviorcited by 16
  8. 2021Tree-Values: selective inference for regression treescited by 15
  9. 2022The Fairness of Credit Scoring Modelscited by 15
  10. 2022Benchmarking Heterogeneous Treatment Effect Models through the Lens of Interpretabilitycited by 15
  11. 2021A Tree-based Model Averaging Approach for Personalized Treatment Effect Estimation from Heterogeneous Data Sourcescited by 14
  12. 2022Differentially Private Estimation of Heterogeneous Causal Effectscited by 14
  13. 2022What's the Harm? Sharp Bounds on the Fraction Negatively Affected by Treatmentcited by 14
  14. 2023Oracle-Efficient Pessimism: Offline Policy Optimization in Contextual Banditscited by 14
  15. 2024The GPT Surprise: Offering Large Language Model Chat in a Massive Coding Class Reduced Engagement but Increased Adopters Exam Performancescited by 14
  16. 2021A Large Scale Benchmark for Individual Treatment Effect Prediction and Uplift Modelingcited by 12
  17. 2022Treatment Effect Risk: Bounds and Inferencecited by 12
  18. 2022Towards assessing agricultural land suitability with causal machine learningcited by 11
  19. 2023Dynamic Inter-treatment Information Sharing for Individualized Treatment Effects Estimationcited by 11
  20. 2021Learning Optimal Prescriptive Trees from Observational Datacited by 10
  21. 2022Comparison of meta-learners for estimating multi-valued treatment heterogeneous effectscited by 10
  22. 2021A cautionary tale on fitting decision trees to data from additive models: generalization lower boundscited by 9
  23. 2023An End-to-End Framework for Marketing Effectiveness Optimization under Budget Constraintcited by 9
  24. 2023On the Actionability of Outcome Predictioncited by 9
  25. 2021Markdowns in E-Commerce Fresh Retail: A Counterfactual Prediction and Multi-Period Optimization Approachcited by 8
  26. 2021Estimating Potential Outcome Distributions with Collaborating Causal Networkscited by 8
  27. 2022Multi-disciplinary fairness considerations in machine learning for clinical trialscited by 8
  28. 2023Machine Learning Who to Nudge: Causal vs Predictive Targeting in a Field Experiment on Student Financial Aid Renewalcited by 8
  29. 2021Shrinkage Bayesian Causal Forests for Heterogeneous Treatment Effects Estimationcited by 7
  30. 2022Sample Constrained Treatment Effect Estimationcited by 7
  31. 2023Proximal Causal Learning of Conditional Average Treatment Effectscited by 7
  32. 2022Constrained Prescriptive Trees via Column Generationcited by 6
  33. 2023Learning When to Treat Business Processes: Prescriptive Process Monitoring with Causal Inference and Reinforcement Learningcited by 6
  34. 2023Fair and Robust Estimation of Heterogeneous Treatment Effects for Policy Learningcited by 6
  35. 2024Hierarchical and Density-based Causal Clusteringcited by 6
  36. 2025On Efficient Estimation of Distributional Treatment Effects under Covariate-Adaptive Randomizationcited by 6
  37. 2021Learning Treatment Effects in Panels with General Intervention Patternscited by 5
  38. 2021Identification of Subgroups With Similar Benefits in Off-Policy Policy Evaluationcited by 5

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