Recursive Partitioning for Heterogeneous Causal Effects
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Abstract (arXiv)
In this paper we study the problems of estimating heterogeneity in causal effects in experimental or observational studies and conducting inference about the magnitude of the differences in treatment effects across subsets of the population. In applications, our method provides a data-driven approach to determine which subpopulations have large or small treatment effects and to test hypotheses about the differences in these effects. For experiments, our method allows researchers to identify heterogeneity in treatment effects that was not specified in a pre-analysis plan, without concern about invalidating inference due to multiple testing. In most of the literature on supervised machine learning (e.g. regression trees, random forests, LASSO, etc.), the goal is to build a model of the relationship between a unit's attributes and an observed outcome. A prominent role in these methods is played by cross-validation which compares predictions to actual outcomes in test samples, in order to select the level of complexity of the model that provides the best predictive power. Our method is closely related, but it differs in that it is tailored for predicting causal effects of a treatment rather than a unit's outcome. The challenge is that the "ground truth" for a causal effect is not observed for any individual unit: we observe the unit with the treatment, or without the treatment, but not both at the same time. Thus, it is not obvious how to use cross-validation to determine whether a causal effect has been accurately predicted. We propose several novel cross-validation criteria for this problem and demonstrate through simulations the conditions under which they perform better than standard methods for the problem of causal effects. We then apply the method to a large-scale field experiment re-ranking results on a search engine.
Key facts. Cited by 254 papers in the map (data through 7 Oct 2026). First posted on arXiv 5 Apr 2015.
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Citing papers per year: 2021: 31; 2022: 40; 2023: 56; 2024: 49; 2025: 40; 2026: 38.
254 papers.
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- 2021Causal Effect Inference for Structured Treatmentscited by 38
- 2021A Review of Generalizability and Transportabilitycited by 36
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- 2023In Search of Insights, Not Magic Bullets: Towards Demystification of the Model Selection Dilemma in Heterogeneous Treatment Effect Estimationcited by 29
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- 2023Explicit Feature Interaction-aware Uplift Network for Online Marketingcited by 25
- 2022Transfer Learning on Heterogeneous Feature Spaces for Treatment Effects Estimationcited by 21
- 2022Image-based Treatment Effect Heterogeneitycited by 20
- 2022Data-Driven Causal Effect Estimation Based on Graphical Causal Modelling: A Surveycited by 19
38 more
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50 most cited of 254 All 254 (JSON)
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50 newest of 254 All 254 (JSON)
- 2024Causal machine learning for predicting treatment outcomescited by 73
- 2025Do-PFN: In-Context Learning for Causal Effect Estimationcited by 46
- 2021Causal Effect Inference for Structured Treatmentscited by 38
- 2021A Review of Generalizability and Transportabilitycited by 36
- 2021Mixed-Integer Optimization with Constraint Learningcited by 30
- 2023In Search of Insights, Not Magic Bullets: Towards Demystification of the Model Selection Dilemma in Heterogeneous Treatment Effect Estimationcited by 29
- 2021Causal Decision Making and Causal Effect Estimation Are Not the Same... and Why It Matterscited by 25
- 2021SurvITE: Learning Heterogeneous Treatment Effects from Time-to-Event Datacited by 25
- 2023Explicit Feature Interaction-aware Uplift Network for Online Marketingcited by 25
- 2022Transfer Learning on Heterogeneous Feature Spaces for Treatment Effects Estimationcited by 21
- 2022Image-based Treatment Effect Heterogeneitycited by 20
- 2022Data-Driven Causal Effect Estimation Based on Graphical Causal Modelling: A Surveycited by 19
12 most cited of 250 All 250 (JSON)
- 2026What You Observe Determines How You Identify Causal Effects: Evaluating Causal Models across Observational Views29 Sep 2026
- 2026The Right Lesson at the Right Step: Deriving Control Updates for Self-Evolving Agents28 Sep 2026
- 2026Climate Variability Modulates the Impact of Price Spikes on Food Insecurity21 Sep 2026
- 2026Splitting the Difference: Interpretable Causal Forests for Treatment Effect Heterogeneity and Bias15 Sep 2026
- 2026Learned Look-Ahead Splitting Rule for CART14 Sep 2026
- 2026Representation Learning for Sample-Efficient CATE Estimation by Leveraging Multiple Outcomes5 Sep 2026
- 2026Generating Intervention Hypotheses using Explainable Explanations on Graphs: G2I, a Two-Stage Greedy Framework24 Aug 2026
- 2026When Can You Trust Offline Evaluation of Equal-Cost Top-k Allocation? A Controlled, Reproducible Benchmark and Practitioner's Guide12 Aug 2026
- 2026Attenuated Heterogeneity in Fixed-Effects Causal Forests, and a Cross-Fitted Correction24 Jul 2026
- 2026TLRNet: Estimating Individual Treatment Effect based on Local Information and Single Learner Structure23 Jul 2026
- 2026Safe Remediation as Risk-Constrained Intervention Decision in Microservice Systems22 Jul 2026
- 2026Counterfactual Optimal Action Trees (COAT): Interpretable Prescriptive Policies from Observational Data15 Jul 2026
12 newest of 250 All 250 (JSON)