mlsanityData to 7 Oct 2026

EvoScientist: Towards Multi-Agent Evolving AI Scientists for End-to-End Scientific Discovery

arXiv 2603.08127 ↗First posted 9 Mar 2026cs.CLcited by 41

On the map: LLM agents and tool use → Web, search, and research agents

Abstract (arXiv)

The increasing adoption of Large Language Models (LLMs) has enabled AI scientists to perform complex end-to-end scientific discovery tasks requiring coordination of specialized roles, including idea generation and experimental execution. However, most state-of-the-art AI scientist systems rely on static, hand-designed pipelines and fail to adapt based on accumulated interaction histories. As a result, these systems overlook promising research directions, repeat failed experiments, and pursue infeasible ideas. To address this, we introduce EvoScientist, an evolving multi-agent AI scientist framework that continuously improves research strategies through persistent memory and self-evolution. EvoScientist comprises three specialized agents: a Researcher Agent (RA) for scientific idea generation, an Engineer Agent (EA) for experiment implementation and execution, and an Evolution Manager Agent (EMA) that distills insights from prior interactions into reusable knowledge. EvoScientist contains two persistent memory modules: (i) an ideation memory, which summarizes feasible research directions from top-ranked ideas while recording previously unsuccessful directions; and (ii) an experimentation memory, which captures effective data processing and model training strategies derived from code search trajectories and best-performing implementations. These modules enable the RA and EA to retrieve relevant prior strategies, improving idea quality and code execution success rates over time. Experiments show that EvoScientist outperforms 7 open-source and commercial state-of-the-art systems in scientific idea generation, achieving higher novelty, feasibility, relevance, and clarity via automatic and human evaluation. EvoScientist also substantially improves code execution success rates through multi-agent evolution, demonstrating persistent memory's effectiveness for end-to-end scientific discovery.

Key facts. Cited by 41 papers in the map (data through 7 Oct 2026). Placed in Web, search, and research agents, one of 16 directions in LLM agents and tool use. Builds on 27 of its 70 references that are in the map. First posted on arXiv 9 Mar 2026.

Builds on

27 of 70 references.

Closest ancestors · 4

Same direction, newest first

  1. 2025Agentic AI for Scientific Discovery: A Survey of Progress, Challenges, and Future Directions12 Mar
  2. 2025Agent Laboratory: Using LLM Agents as Research Assistants8 Jan
  3. 2024Many Heads Are Better Than One: Improved Scientific Idea Generation by A LLM-Based Multi-Agent System12 Oct
  4. 2024Can LLMs Generate Novel Research Ideas? A Large-Scale Human Study with 100+ NLP Researchers6 Sep

Other references · 23

  1. 2023Judging LLM-as-a-Judge with MT-Bench and Chatbot Arenacited by 8,393
  2. 2023Reflexion: Language Agents with Verbal Reinforcement Learningcited by 4,064
  3. 2023ExpeL: LLM Agents Are Experiential Learnerscited by 814
  4. 2025Mem0: Building Production-Ready AI Agents with Scalable Long-Term Memorycited by 722
  5. 2025Darwin Godel Machine: Open-Ended Evolution of Self-Improving Agentscited by 294
  6. 2025Alita: Generalist Agent Enabling Scalable Agentic Reasoning with Minimal Predefinition and Maximal Self-Evolutioncited by 114
  7. 2020Look at the First Sentence: Position Bias in Question Answeringcited by 83
  8. 2025AgentRxiv: Towards Collaborative Autonomous Researchcited by 64
  9. 2025ResearchBench: Benchmarking LLMs in Scientific Discovery via Inspiration-Based Task Decompositioncited by 57
  10. 2025DeepScientist: Advancing Frontier-Pushing Scientific Findings Progressivelycited by 56
  11. 2025AI4Research: A Survey of Artificial Intelligence for Scientific Researchcited by 54
  12. 2025DeepShop: A Benchmark for Deep Research Shopping Agentscited by 42
11 more
  1. 2024Towards Scientific Discovery with Generative AI: Progress, Opportunities, and Challengescited by 41
  2. 2024Large Language Models as Biomedical Hypothesis Generators: A Comprehensive Evaluationcited by 33
  3. 2025ResearcherBench: Evaluating Deep AI Research Systems on the Frontiers of Scientific Inquirycited by 30
  4. 2025Sparks of Science: Hypothesis Generation Using Structured Paper Datacited by 22
  5. 2024MACPO: Weak-to-Strong Alignment via Multi-Agent Contrastive Preference Optimizationcited by 20
  6. 2025Uni-X: Mitigating Modality Conflict with a Two-End-Separated Architecture for Unified Multimodal Modelscited by 18
  7. 2023Multi-Defendant Legal Judgment Prediction via Hierarchical Reasoningcited by 17
  8. 2025One Size doesn't Fit All: A Personalized Conversational Tutoring Agent for Mathematics Instructioncited by 17
  9. 2025A Token is Worth over 1,000 Tokens: Efficient Knowledge Distillation through Low-Rank Clonecited by 15
  10. 2025OmniScientist: Toward a Co-evolving Ecosystem of Human and AI Scientistscited by 15
  11. 2024Cognitive Biases in Large Language Models for News Recommendationcited by 6

Built on by

Cited by year (2026 to 7 Oct)

Citing papers per year: 2026: 41.

41 papers.

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By area:

  1. 2026Recursive Self-Improvement in AI: From Bounded Self-Refinement to Autonomous Research Loopscited by 25
  2. 2026ScientistOne: Towards Human-Level Autonomous Research via Chain-of-Evidencecited by 15
  3. 2026ARIS: Autonomous Research via Adversarial Multi-Agent Collaborationcited by 12
  4. 2026AutoResearch AI: Towards AI-Powered Research Automation for Scientific Discoverycited by 9
  5. 2026From Question Answering to Task Completion: A Survey on Agent System and Harness Designcited by 9
  6. 2026NatureBench: Can Coding Agents Match the Published SOTA of Nature-Family Papers?cited by 9
  7. 2026Can LLMs Write Reliable Rubrics? A Meta-Evaluation for Experiment Reproductioncited by 6
  8. 2026The Last AI Built by Humans: Toward Genuine Recursive Self-Improvementcited by 5
  9. 2026NeuroClaw Technical Reportcited by 4
  10. 2026NanoResearch: Co-Evolving Skills, Memory, and Policy for Personalized Research Automationcited by 4
  11. 2026GEAR: Genetic AutoResearch for Agentic Code Evolutioncited by 4
  12. 2026AutoSci: A Memory-Centric Agentic System for the Full Scientific Research Lifecyclecited by 4
29 more
  1. 2026An Empirical Study of Multi-Agent Collaboration for Automated Researchcited by 3
  2. 2026Symbolic-Vector Attention Fusion for Collective Intelligencecited by 3
  3. 2026TianJi:An autonomous AI meteorologist for discovering physical mechanisms in atmospheric sciencecited by 2
  4. 2026Federation over Text: Insight Sharing for Multi-Agent Reasoningcited by 2
  5. 2026Toward AI VIS Co-Scientists: A General and End-to-End Agent Harness for Solving Complex Data Visualization Taskscited by 2
  6. 2026Socratic agents for autonomous scientific discovery in high-dimensional physical systemscited by 2
  7. 2026Overview of the NLPCC 2026 Shared Task 11: Agent-Based Experiment Reproduction from Scientific Paperscited by 2
  8. 2026Deep Research of Deep Research: From Transformer to Agent, From AI to AI for Sciencecited by 1
  9. 2026SciAtlas: A Computable Atlas of Science for Knowledge-Grounded AI Researchcited by 1
  10. 2026One Reflection Is Not Enough: Self-Correcting Autonomous Research via Multi-Hypothesis Failure Attributioncited by 1
  11. 2026Co-Evolution in Agentic Systems: Toward Self-Directed Evolution Beyond Human Designcited by 1
  12. 2026Can LLM Agents Discover? Evaluating Creativity on ML Engineering Taskscited by 1
  13. 2026The Emerging AI Paper-Review Arms Race: Adversarial Co-Evolution in Scholarly Publishingcited by 1
  14. 2026Auto-RecSys: Harnessing Autonomous Research Agents for Industry-Scale Recommender Systemcited by 1
  15. 2026Toward Vibe Medicine: A Self-Evolving Multi-Agent Framework for Clinical Decision Supportcited by 0
  16. 2026PseudoBench: Measuring How Agentic Auto-Research Fuels Pseudosciencecited by 0
  17. 2026Rehearse: Stepping Back from the Confidence Cliff in Self-Improving Autoresearchcited by 0
  18. 2026Diversifying Personalized Research Ideation against AI-Induced Homogenizationcited by 0
  19. 2026Towards a new paradigm of scientific discovery with socialized artificial intelligencecited by 0
  20. 2026ARAC: Benchmarking Auto-Research's Alignment and Completeness on End-to-End Researchscited by 0
  21. 2026Position: AI Agents in Scientific Teams Should Be Studied as Human-Agent Systemscited by 0
  22. 2026Competing at Every Price Point with Agentic Evolution over a Menu of LLMscited by 0
  23. 2026OpenAI4S: Code as Action, Science as Sessionscited by 0
  24. 2026BizSage: A Self-Evolving Multi-Agent Framework for Business Research with Efficient Knowledge Retrievalcited by 0
  25. 2026Collaborative Principle Evolution via Evidence Transfer for Scientific Discoverycited by 0
  26. 2026Faithful Chart Generation for Multimodal Deep Research: Frame-Evidence Co-Adaptationcited by 0
  27. 2026EurekaBench: Measuring Agentic Ability to Discover New Scientific Insightscited by 0
  28. 2026Can AI Scientists Coordinate at Runtime?cited by 0
  29. 2026EvoSim: Learning to Model, Modeling to Learncited by 0

Similar, not cited

Close in wording, no citation either way

  1. 2026EvoSci: A Bio-Inspired Multi-Agent Framework for the Evolution of Scientific Discovery
  2. 2026EvoMaster: A Foundational Evolving Agent Framework for Agentic Science at Scale
  3. 2026Toward Auditable AI Scientists: A Hypothesis Evolution Protocol for LLM Agents
  4. 2025Autonomous Agents for Scientific Discovery: Orchestrating Scientists, Language, Code, and Physics
  5. 2026InternAgent-1.5: A Unified Agentic Framework for Long-Horizon Autonomous Scientific Discovery
  6. 2025InnovatorBench: Evaluating Agents' Ability to Conduct Innovative LLM Research
  7. 2026EvoSCM: Scientific Belief Revision Through Causal Model Evolution and Experimentation
  8. 2026CausalEvolve: Towards Open-Ended Discovery with Causal Scratchpad