OmniScientist: Toward a Co-evolving Ecosystem of Human and AI Scientists
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Abstract (arXiv)
With the rapid development of Large Language Models (LLMs), AI agents have demonstrated increasing proficiency in scientific tasks, ranging from hypothesis generation and experimental design to manuscript writing. Such agent systems are commonly referred to as "AI Scientists." However, existing AI Scientists predominantly formulate scientific discovery as a standalone search or optimization problem, overlooking the fact that scientific research is inherently a social and collaborative endeavor. Real-world science relies on a complex scientific infrastructure composed of collaborative mechanisms, contribution attribution, peer review, and structured scientific knowledge networks. Due to the lack of modeling for these critical dimensions, current systems struggle to establish a genuine research ecosystem or interact deeply with the human scientific community. To bridge this gap, we introduce OmniScientist, a framework that explicitly encodes the underlying mechanisms of human research into the AI scientific workflow. OmniScientist not only achieves end-to-end automation across data foundation, literature review, research ideation, experiment automation, scientific writing, and peer review, but also provides comprehensive infrastructural support by simulating the human scientific system, comprising: (1) a structured knowledge system built upon citation networks and conceptual correlations; (2) a collaborative research protocol (OSP), which enables seamless multi-agent collaboration and human researcher participation; and (3) an open evaluation platform (ScienceArena) based on blind pairwise user voting and Elo rankings. This infrastructure empowers agents to not only comprehend and leverage human knowledge systems but also to collaborate and co-evolve, fostering a sustainable and scalable innovation ecosystem.
Key facts. Cited by 18 papers in the map (data through 14 Oct 2026). Builds on 28 of its 43 references that are in the map. First posted on arXiv 21 Nov 2025.
Builds on
28 of 43 references.
References · 28
- 2023Tree of Thoughts: Deliberate Problem Solving with Large Language Modelscited by 3,211
- 2024The AI Scientist: Towards Fully Automated Open-Ended Scientific Discoverycited by 1,071
- 2025AlphaEvolve: A coding agent for scientific and algorithmic discoverycited by 867
- 2025Humanity's Last Examcited by 491
- 2025Agent Laboratory: Using LLM Agents as Research Assistantscited by 425
- 2025The AI Scientist-v2: Workshop-Level Automated Scientific Discovery via Agentic Tree Searchcited by 422
- 2025Accelerating scientific discovery with Co-Scientistcited by 401
- 2024Justice or Prejudice? Quantifying Biases in LLM-as-a-Judgecited by 368
- 2024Humans or LLMs as the Judge? A Study on Judgement Biasescited by 323
- 2024ResearchAgent: Iterative Research Idea Generation over Scientific Literature with Large Language Modelscited by 210
- 2023Can large language models provide useful feedback on research papers? A large-scale empirical analysiscited by 200
- 2023SciMON: Scientific Inspiration Machines Optimized for Noveltycited by 179
16 more
- 2024CycleResearcher: Improving Automated Research via Automated Reviewcited by 148
- 2024MARG: Multi-Agent Review Generation for Scientific Paperscited by 104
- 2025DeepReview: Improving LLM-based Paper Review with Human-like Deep Thinking Processcited by 100
- 2024MOOSE-Chem: Large Language Models for Rediscovering Unseen Chemistry Scientific Hypothesescited by 72
- 2024OpenReviewer: A Specialized Large Language Model for Generating Critical Scientific Paper Reviewscited by 65
- 2025DeepScientist: Advancing Frontier-Pushing Scientific Findings Progressivelycited by 63
- 2025Large language models for automated scholarly paper review: A surveycited by 61
- 2024CRISPR-GPT for Agentic Automation of Gene-editing Experimentscited by 58
- 2024Automated Peer Reviewing in Paper SEA: Standardization, Evaluation, and Analysiscited by 33
- 2025TreeReview: A Dynamic Tree of Questions Framework for Deep and Efficient LLM-based Scientific Peer Reviewcited by 31
- 2023Accelerating science with human-aware artificial intelligencecited by 28
- 2024Stochastic Taylor Derivative Estimator: Efficient amortization for arbitrary differential operatorscited by 20
- 2025ReviewRL: Towards Automated Scientific Review with RLcited by 19
- 2024LLMs as Meta-Reviewers' Assistants: A Case Studycited by 16
- 2023DataFinder: Scientific Dataset Recommendation from Natural Language Descriptionscited by 15
- 2025REMOR: Automated Peer Review Generation with LLM Reasoning and Multi-Objective Reinforcement Learningcited by 11
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Citing papers per year: 2026: 18.
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- 2026EvoScientist: Towards Multi-Agent Evolving AI Scientists for End-to-End Scientific Discoverycited by 51
- 2026AutoResearchClaw: Self-Reinforcing Autonomous Research with Human-AI Collaborationcited by 25
- 2026AutoSOTA: An End-to-End Automated Research System for State-of-the-Art AI Model Discoverycited by 23
- 2026PaperOrchestra: A Multi-Agent Framework for Automated AI Research Paper Writingcited by 13
- 2026AutoResearch AI: Towards AI-Powered Research Automation for Scientific Discoverycited by 10
- 2026InnoEval: On Research Idea Evaluation as a Knowledge-Grounded, Multi-Perspective Reasoning Problemcited by 8
- 2026Human Cognition in Machines: A Unified Perspective of World Modelscited by 5
- 2026NanoResearch: Co-Evolving Skills, Memory, and Policy for Personalized Research Automationcited by 4
- 2026Toward AI VIS Co-Scientists: A General and End-to-End Agent Harness for Solving Complex Data Visualization Taskscited by 3
- 2026OmniScientist: An Omni-Modal Omni-Discipline AI Scientistcited by 1
- 2026Grounding LLMs in Scientific Discovery via Embodied Actionscited by 0
- 2026AgentEconomist: An End-to-end Agentic System Translating Economic Intuitions into Executable Computational Experimentscited by 0
6 more
- 2026AiraXiv: An AI-Driven Open-Access Platform for Human and AI Scientistscited by 0
- 2026Position: AI Agents in Scientific Teams Should Be Studied as Human-Agent Systemscited by 0
- 2026Paper Pilot: A Human-in-the-Loop Expert System for Evidence-Traceable Scientific Manuscript Generation in Applied Sciencescited by 0
- 2026InternReviewer & InternAdvocate: Objective Reward and Evaluation for Agentic Reinforcement Learning in Peer Review and Rebuttalcited by 0
- 2026TRIZa: Guiding Agent Evolution from Pattern Recognition to Solution Inventioncited by 0
- 2026ST-Bench: A Spatial-Temporal Benchmark for Multi-Agent System Generation on Scientific Research Taskscited by 0
- 2026ST-Bench: A Spatial-Temporal Benchmark for Multi-Agent System Generation on Scientific Research Tasks6 Oct 2026
- 2026TRIZa: Guiding Agent Evolution from Pattern Recognition to Solution Invention3 Oct 2026
- 2026OmniScientist: An Omni-Modal Omni-Discipline AI Scientist13 Aug 2026
- 2026Position: AI Agents in Scientific Teams Should Be Studied as Human-Agent Systems2 Aug 2026
- 2026InternReviewer & InternAdvocate: Objective Reward and Evaluation for Agentic Reinforcement Learning in Peer Review and Rebuttal21 Jul 2026
- 2026Paper Pilot: A Human-in-the-Loop Expert System for Evidence-Traceable Scientific Manuscript Generation in Applied Sciences17 Jun 2026
- 2026AutoResearch AI: Towards AI-Powered Research Automation for Scientific Discovery22 May 2026
- 2026Toward AI VIS Co-Scientists: A General and End-to-End Agent Harness for Solving Complex Data Visualization Tasks20 May 2026
- 2026AiraXiv: An AI-Driven Open-Access Platform for Human and AI Scientists20 May 2026
- 2026AutoResearchClaw: Self-Reinforcing Autonomous Research with Human-AI Collaboration19 May 2026
- 2026NanoResearch: Co-Evolving Skills, Memory, and Policy for Personalized Research Automation11 May 2026
- 2026AgentEconomist: An End-to-end Agentic System Translating Economic Intuitions into Executable Computational Experiments30 Apr 2026
6 more
- 2026Human Cognition in Machines: A Unified Perspective of World Models17 Apr 2026
- 2026AutoSOTA: An End-to-End Automated Research System for State-of-the-Art AI Model Discovery7 Apr 2026
- 2026PaperOrchestra: A Multi-Agent Framework for Automated AI Research Paper Writing6 Apr 2026
- 2026EvoScientist: Towards Multi-Agent Evolving AI Scientists for End-to-End Scientific Discovery9 Mar 2026
- 2026Grounding LLMs in Scientific Discovery via Embodied Actions24 Feb 2026
- 2026InnoEval: On Research Idea Evaluation as a Knowledge-Grounded, Multi-Perspective Reasoning Problem16 Feb 2026
- 2026EvoScientist: Towards Multi-Agent Evolving AI Scientists for End-to-End Scientific Discoverycited by 51
- 2026NanoResearch: Co-Evolving Skills, Memory, and Policy for Personalized Research Automationcited by 4
- 2026AgentEconomist: An End-to-end Agentic System Translating Economic Intuitions into Executable Computational Experimentscited by 0
- 2026Position: AI Agents in Scientific Teams Should Be Studied as Human-Agent Systemscited by 0
- 2026InternReviewer & InternAdvocate: Objective Reward and Evaluation for Agentic Reinforcement Learning in Peer Review and Rebuttalcited by 0
- 2026TRIZa: Guiding Agent Evolution from Pattern Recognition to Solution Inventioncited by 0
- 2026ST-Bench: A Spatial-Temporal Benchmark for Multi-Agent System Generation on Scientific Research Taskscited by 0
- 2026ST-Bench: A Spatial-Temporal Benchmark for Multi-Agent System Generation on Scientific Research Tasks6 Oct 2026
- 2026TRIZa: Guiding Agent Evolution from Pattern Recognition to Solution Invention3 Oct 2026
- 2026Position: AI Agents in Scientific Teams Should Be Studied as Human-Agent Systems2 Aug 2026
- 2026InternReviewer & InternAdvocate: Objective Reward and Evaluation for Agentic Reinforcement Learning in Peer Review and Rebuttal21 Jul 2026
- 2026NanoResearch: Co-Evolving Skills, Memory, and Policy for Personalized Research Automation11 May 2026
- 2026AgentEconomist: An End-to-end Agentic System Translating Economic Intuitions into Executable Computational Experiments30 Apr 2026
- 2026EvoScientist: Towards Multi-Agent Evolving AI Scientists for End-to-End Scientific Discovery9 Mar 2026
- 2026AutoResearchClaw: Self-Reinforcing Autonomous Research with Human-AI Collaborationcited by 25
- 2026AutoSOTA: An End-to-End Automated Research System for State-of-the-Art AI Model Discoverycited by 23
- 2026PaperOrchestra: A Multi-Agent Framework for Automated AI Research Paper Writingcited by 13
- 2026AutoResearch AI: Towards AI-Powered Research Automation for Scientific Discoverycited by 10
- 2026Toward AI VIS Co-Scientists: A General and End-to-End Agent Harness for Solving Complex Data Visualization Taskscited by 3
- 2026OmniScientist: An Omni-Modal Omni-Discipline AI Scientistcited by 1
- 2026Grounding LLMs in Scientific Discovery via Embodied Actionscited by 0
- 2026AiraXiv: An AI-Driven Open-Access Platform for Human and AI Scientistscited by 0
- 2026Paper Pilot: A Human-in-the-Loop Expert System for Evidence-Traceable Scientific Manuscript Generation in Applied Sciencescited by 0
- 2026OmniScientist: An Omni-Modal Omni-Discipline AI Scientist13 Aug 2026
- 2026Paper Pilot: A Human-in-the-Loop Expert System for Evidence-Traceable Scientific Manuscript Generation in Applied Sciences17 Jun 2026
- 2026AutoResearch AI: Towards AI-Powered Research Automation for Scientific Discovery22 May 2026
- 2026Toward AI VIS Co-Scientists: A General and End-to-End Agent Harness for Solving Complex Data Visualization Tasks20 May 2026
- 2026AiraXiv: An AI-Driven Open-Access Platform for Human and AI Scientists20 May 2026
- 2026AutoResearchClaw: Self-Reinforcing Autonomous Research with Human-AI Collaboration19 May 2026
- 2026AutoSOTA: An End-to-End Automated Research System for State-of-the-Art AI Model Discovery7 Apr 2026
- 2026PaperOrchestra: A Multi-Agent Framework for Automated AI Research Paper Writing6 Apr 2026
- 2026Grounding LLMs in Scientific Discovery via Embodied Actions24 Feb 2026