mlsanityData to 14 Oct 2026

Expressing stigma and inappropriate responses prevents LLMs from safely replacing mental health providers

arXiv 2504.18412 ↗First posted 25 Apr 2025cs.CLcited by 69

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Abstract (arXiv)

Should a large language model (LLM) be used as a therapist? In this paper, we investigate the use of LLMs to *replace* mental health providers, a use case promoted in the tech startup and research space. We conduct a mapping review of therapy guides used by major medical institutions to identify crucial aspects of therapeutic relationships, such as the importance of a therapeutic alliance between therapist and client. We then assess the ability of LLMs to reproduce and adhere to these aspects of therapeutic relationships by conducting several experiments investigating the responses of current LLMs, such as `gpt-4o`. Contrary to best practices in the medical community, LLMs 1) express stigma toward those with mental health conditions and 2) respond inappropriately to certain common (and critical) conditions in naturalistic therapy settings -- e.g., LLMs encourage clients' delusional thinking, likely due to their sycophancy. This occurs even with larger and newer LLMs, indicating that current safety practices may not address these gaps. Furthermore, we note foundational and practical barriers to the adoption of LLMs as therapists, such as that a therapeutic alliance requires human characteristics (e.g., identity and stakes). For these reasons, we conclude that LLMs should not replace therapists, and we discuss alternative roles for LLMs in clinical therapy.

Key facts. Cited by 69 papers in the map (data through 14 Oct 2026). Builds on 32 of its 164 references that are in the map. First posted on arXiv 25 Apr 2025.

Builds on

32 of 164 references.

References · 32

  1. 2023Efficient Memory Management for Large Language Model Serving with PagedAttentioncited by 5,944
  2. 2023Lost in the Middle: How Language Models Use Long Contextscited by 3,455
  3. 2023Evaluating and Mitigating Discrimination in Language Model Decisionscited by 124
  4. 2023Understanding the Benefits and Challenges of Using Large Language Model-based Conversational Agents for Mental Well-being Supportcited by 75
  5. 2024Roleplay-doh: Enabling Domain-Experts to Create LLM-simulated Patients via Eliciting and Adhering to Principlescited by 73
  6. 2022Human-AI Collaboration Enables More Empathic Conversations in Text-based Peer-to-Peer Mental Health Supportcited by 68
  7. 2024Are Large Language Models Consistent over Value-laden Questions?cited by 58
  8. 2024SimpleToM: Exposing the Gap between Explicit ToM Inference and Implicit ToM Application in LLMscited by 57
  9. 2024The opportunities and risks of large language models in mental healthcited by 54
  10. 2023Facilitating Self-Guided Mental Health Interventions Through Human-Language Model Interaction: A Case Study of Cognitive Restructuringcited by 53
  11. 2019Roles for Computing in Social Changecited by 49
  12. 2024Beyond Preferences in AI Alignmentcited by 49
20 more
  1. 2024HealMe: Harnessing Cognitive Reframing in Large Language Models for Psychotherapycited by 47
  2. 2024Interactive Agents: Simulating Counselor-Client Psychological Counseling via Role-Playing LLM-to-LLM Interactionscited by 43
  3. 2022The Turing Trap: The Promise & Peril of Human-Like Artificial Intelligencecited by 42
  4. 2023Benefits and Harms of Large Language Models in Digital Mental Healthcited by 40
  5. 2025Investigating Affective Use and Emotional Well-being on ChatGPTcited by 38
  6. 2024Addressing cognitive bias in medical language modelscited by 36
  7. 2024Large Language Models Produce Responses Perceived to be Empathiccited by 36
  8. 2022Inducing Positive Perspectives with Text Reframingcited by 31
  9. 2024Bias patterns in the application of LLMs for clinical decision support: A comprehensive studycited by 27
  10. 2024Risks from Language Models for Automated Mental Healthcare: Ethics and Structure for Implementationcited by 27
  11. 2024A Philosophical Introduction to Language Models -- Part I: Continuity With Classic Debatescited by 23
  12. 2024Intelligent Clinical Documentation: Harnessing Generative AI for Patient-Centric Clinical Note Generationcited by 20
  13. 2022Exploring The Design of Prompts For Applying GPT-3 based Chatbots: A Mental Wellbeing Case Study on Mechanical Turkcited by 13
  14. 2024Large Language Models are Capable of Offering Cognitive Reappraisal, if Guidedcited by 13
  15. 2024Acceptable Use Policies for Foundation Modelscited by 12
  16. 2025A Survey of Large Language Models in Psychotherapy: Current Landscape and Future Directionscited by 12
  17. 2023Deep Learning Mental Health Dialogue Systemcited by 9
  18. 2024Response Generation for Cognitive Behavioral Therapy with Large Language Models: Comparative Study with Socratic Questioningcited by 8
  19. 2024Language Models as Critical Thinking Tools: A Case Study of Philosopherscited by 6
  20. 2024Enhancing Psychotherapy Counseling: A Data Augmentation Pipeline Leveraging Large Language Models for Counseling Conversationscited by 3

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Cited by year (2026 to 14 Oct)

Citing papers per year: 2025: 18; 2026: 51.

69 papers.

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  1. 2025ELEPHANT: Measuring and understanding social sycophancy in LLMscited by 129
  2. 2025Consistently Simulating Human Personas with Multi-Turn Reinforcement Learningcited by 39
  3. 2026Characterizing Delusional Spirals through Human-LLM Chat Logscited by 23
  4. 2025When Large Language Models are Reliable for Judging Empathic Communicationcited by 21
  5. 2025Large language models provide unsafe answers to patient-posed medical questionscited by 18
  6. 2025Technological folie `a deux: Feedback Loops Between AI Chatbots and Mental Illnesscited by 15
  7. 2025Taxonomy of User Needs and Actionscited by 15
  8. 2025The Psychogenic Machine: Simulating AI Psychosis, Delusion Reinforcement and Harm Enablement in Large Language Modelscited by 11
  9. 2025Do Large Language Models Have a Planning Theory of Mind? Evidence from MindGames: a Multi-Step Persuasion Taskcited by 9
  10. 2025Digital Companionship: Overlapping Uses of AI Companions and AI Assistantscited by 7
  11. 2026PAIR-SAFE: A Paired-Agent Approach for Runtime Auditing and Refining AI-Mediated Mental Health Supportcited by 7
  12. 2025Sycophantic AI Decreases Prosocial Intentions and Promotes Dependencecited by 6
38 more
  1. 2025Tailored Emotional LLM-Supporter: Enhancing Cultural Sensitivitycited by 5
  2. 2026Beyond Simulations: What 20,000 Real Conversations Reveal About Mental Health AI Safetycited by 4
  3. 2026AI Chatbot Suicide Risk Detection and Response: Human Validation Study of the Open-Source VERA-MH Safety Evaluationcited by 4
  4. 2025DialogGuard: Multi-Agent Psychosocial Safety Evaluation of Sensitive LLM Responsescited by 3
  5. 2025When AI Gives Advice: Evaluating AI and Human Responses to Online Advice-Seeking for Well-Beingcited by 3
  6. 2026MindGuard: Guardrail Classifiers for Multi-Turn Mental Health Supportcited by 3
  7. 2026Are Language Models Sensitive to Morally Irrelevant Distractors?cited by 3
  8. 2026Assessing Risks of Large Language Models in Mental Health Support: A Framework for Automated Clinical AI Red Teamingcited by 3
  9. 2026One Bias After Another: Mechanistic Reward Shaping and Persistent Biases in Language Reward Modelscited by 3
  10. 2026Using LLM-as-a-Judge/Jury to Advance Scalable, Clinically-Validated Safety Evaluations of Model Responses to Users Demonstrating Psychosiscited by 3
  11. 2026AI generates well-liked but templatic empathic responsescited by 3
  12. 2025Seeking Late Night Life Lines: Experiences of Conversational AI Use in Mental Health Crisiscited by 2
  13. 2026Regulatory gray areas of LLM Termscited by 2
  14. 2026Expert Evaluation and the Limits of Human Feedback in Mental Health AI Safety Testingcited by 2
  15. 2026Understanding Risk and Dependency in AI Chatbot Use from User Discoursecited by 2
  16. 2026Brainrot: Deskilling and Addiction are Overlooked AI Riskscited by 2
  17. 2026LLUMI: Improving LLM Writing Assistance for Mental Health Support with Online Community Feedbackcited by 2
  18. 2025Generative AI Purpose-built for Social and Mental Health: A Real-World Pilotcited by 1
  19. 2025Big AI is accelerating the metacrisis: What can we do?cited by 1
  20. 2025AI for Proactive Mental Health: A Multi-Institutional, Longitudinal, Randomized Controlled Trialcited by 1
  21. 2026A Checklist for Trustworthy, Safe, and User-Friendly Mental Health Chatbotscited by 1
  22. 2026A Conditional Companion: Lived Experiences of People with Mental Health Disorders Using LLMscited by 1
  23. 2026Chaplains' Reflections on the Design and Usage of AI for Conversational Carecited by 1
  24. 2026What is Safety? Corporate Discourse, Power, and the Politics of Generative AI Safetycited by 1
  25. 2026Common Sense vs. Morality: The Curious Case of Narrative Focus Bias in LLMscited by 1
  26. 2026TherapyGym: Evaluating and Aligning Clinical Fidelity and Safety in Therapy Chatbotscited by 1
  27. 2026Investigating the Influence of Language on Sycophantic Behavior of Multilingual LLMscited by 1
  28. 2026Lost in Delusion: Examining LLM Safety Under User Delusions and Distresscited by 1
  29. 2026CAREBench: A Child-Safety Risk Benchmark for Language Modelscited by 1
  30. 2026Is Convergence Inevitable? Tracing Output Homogeneity Back to Base Modelscited by 1
  31. 2025PolicyPad: Collaborative Prototyping of LLM Policiescited by 0
  32. 2026How Human is AI? Examining the Impact of Emotional Prompts on Artificial and Human and Responsivenesscited by 0
  33. 2026Generative Confidants: How do People Experience Trust in Emotional Support from Generative AI?cited by 0
  34. 2026Initial Risk Probing and Feasibility Testing of Glow: a Generative AI-Powered Dialectical Behavior Therapy Skills Coach for Substance Use Recovery and HIV Preventioncited by 0
  35. 2026Now You See Me: Designing Responsible AI Dashboards for Early-Stage Health Innovationcited by 0
  36. 2026Depictions of Depression in Generative AI Video Models: A Preliminary Study of OpenAI's Sora 2cited by 0
  37. 2026CounselReflect: Opportunities and Challenges for Designing Tools to Support Self-Reflection on Mental Health and Well-Being Conversations with AIcited by 0
  38. 2026Breakdowns in Conversational AI: Interactional Failures in Emotionally and Ethically Sensitive Contextscited by 0

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