Polyp-SAM: Transfer SAM for Polyp Segmentation
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Abstract (arXiv)
Colon polyps are considered important precursors for colorectal cancer. Automatic segmentation of colon polyps can significantly reduce the misdiagnosis of colon cancer and improve physician annotation efficiency. While many methods have been proposed for polyp segmentation, training large-scale segmentation networks with limited colonoscopy data remains a challenge. Recently, the Segment Anything Model (SAM) has recently gained much attention in both natural and medical image segmentation. SAM demonstrates superior performance in several image benchmarks and therefore shows great potential for medical image segmentation. In this study, we propose Poly-SAM, a finetuned SAM model for polyp segmentation, and compare its performance to several state-of-the-art polyp segmentation models. We also compare two transfer learning strategies of SAM with and without finetuning its encoders. Evaluated on five public datasets, our Polyp-SAM achieves state-of-the-art performance on two datasets and impressive performance on three datasets, with dice scores all above 88%. This study demonstrates the great potential of adapting SAM to medical image segmentation tasks. We plan to release the code and model weights for this paper at: https://github.com/ricklisz/Polyp-SAM.
Key facts. Cited by 64 papers in the map (data through 7 Oct 2026). Builds on 13 of its 27 references that are in the map. First posted on arXiv 29 Apr 2023.
Builds on
13 of 27 references.
References · 13
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
- 2023Segment Anythingcited by 8,158
- 2018UNet++: A Nested U-Net Architecture for Medical Image Segmentationcited by 1,518
- 2019Kvasir-SEG: A Segmented Polyp Datasetcited by 588
- 2020PraNet: Parallel Reverse Attention Network for Polyp Segmentationcited by 460
- 2019Transfusion: Understanding Transfer Learning for Medical Imagingcited by 366
- 2021Polyp-PVT: Polyp Segmentation with Pyramid Vision Transformerscited by 159
- 2021Context-aware Cross-level Fusion Network for Camouflaged Object Detectioncited by 86
- 2023SAM.MD: Zero-shot medical image segmentation capabilities of the Segment Anything Modelcited by 61
- 2023Lesion-aware Dynamic Kernel for Polyp Segmentationcited by 39
- 2023SkinSAM: Empowering Skin Cancer Segmentation with Segment Anything Modelcited by 32
- 2023Advancing Medical Imaging with Language Models: A Journey from N-grams to ChatGPTcited by 28
1 more
- 2021Duplex Contextual Relation Network for Polyp Segmentationcited by 22
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Citing papers per year: 2023: 23; 2024: 24; 2025: 11; 2026: 6.
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- 2024Segment Anything Model for Medical Image Segmentation: Current Applications and Future Directionscited by 97
- 2023A Comprehensive Survey on Segment Anything Model for Vision and Beyondcited by 64
- 2024Unleashing the Potential of SAM for Medical Adaptation via Hierarchical Decodingcited by 48
- 2023A Survey on Segment Anything Model (SAM): Vision Foundation Model Meets Prompt Engineeringcited by 45
- 2024How to build the best medical image segmentation algorithm using foundation models: a comprehensive empirical study with Segment Anything Modelcited by 32
- 2024DarkSAM: Fooling Segment Anything Model to Segment Nothingcited by 32
- 2024Interactive Medical Image Segmentation: A Benchmark Dataset and Baselinecited by 30
- 2024Foundation Models for Biomedical Image Segmentation: A Surveycited by 28
- 2024Data-Centric Foundation Models in Computational Healthcare: A Surveycited by 27
- 2024Segment anything model 2: an application to 2D and 3D medical imagescited by 27
- 2023DeSAM: Decoupled Segment Anything Model for Generalizable Medical Image Segmentationcited by 26
- 2023Deep Interactive Segmentation of Medical Images: A Systematic Review and Taxonomycited by 26
38 more
- 2025MedDINOv3: How to adapt vision foundation models for medical image segmentation?cited by 25
- 2023On the Robustness of Segment Anythingcited by 24
- 2023Segment Anything Model (SAM) for Radiation Oncologycited by 24
- 2023An Empirical Study on the Robustness of the Segment Anything Model (SAM)cited by 23
- 2023SAM-PARSER: Fine-tuning SAM Efficiently by Parameter Space Reconstructioncited by 23
- 2023Polyp-SAM++: Can A Text Guided SAM Perform Better for Polyp Segmentation?cited by 22
- 2023Towards Segment Anything Model (SAM) for Medical Image Segmentation: A Surveycited by 21
- 2023Text Augmented Spatial-aware Zero-shot Referring Image Segmentationcited by 21
- 2023Learning the What and How of Annotation in Video Object Segmentationcited by 19
- 2023Self-Sampling Meta SAM: Enhancing Few-shot Medical Image Segmentation with Meta-Learningcited by 18
- 2024SAFIRE: Segment Any Forged Image Regioncited by 18
- 2024MedSAM-U: Uncertainty-Guided Auto Multi-Prompt Adaptation for Reliable MedSAMcited by 17
- 2024On Efficient Variants of Segment Anything Model: A Surveycited by 16
- 2023Full-dose Whole-body PET Synthesis from Low-dose PET Using High-efficiency Denoising Diffusion Probabilistic Model: PET Consistency Modelcited by 15
- 2023mathrmSAMMed: A medical image annotation framework based on large vision modelcited by 13
- 2023A Survey on Deep Learning for Polyp Segmentation: Techniques, Challenges and Future Trendscited by 12
- 2023When SAM Meets Sonar Imagescited by 10
- 2023EviPrompt: A Training-Free Evidential Prompt Generation Method for Segment Anything Model in Medical Imagescited by 8
- 2024Boosting Medical Image Classification with Segmentation Foundation Modelcited by 8
- 2024Polyp SAM 2: Advancing Zero shot Polyp Segmentation in Colorectal Cancer Detectioncited by 8
- 2025Surgical Scene Understanding in the Era of Foundation AI Models: A Comprehensive Reviewcited by 8
- 2025Recent Advances in Medical Imaging Segmentation: A Surveycited by 8
- 2025SAMed-2: Selective Memory Enhanced Medical Segment Anything Modelcited by 8
- 2023BreastSAM: A Study of Segment Anything Model for Breast Tumor Detection in Ultrasound Imagescited by 7
- 2024Self-Prompting Polyp Segmentation in Colonoscopy using Hybrid Yolo-SAM 2 Modelcited by 6
- 2025MedicoSAM: Robust Improvement of SAM for Medical Imagingcited by 6
- 2024Polyp-DAM: Polyp segmentation via depth anything modelcited by 5
- 2024SAMCT: Segment Any CT Allowing Labor-Free Task-Indicator Promptscited by 5
- 2023Industrial Segment Anything -- a Case Study in Aircraft Manufacturing, Intralogistics, Maintenance, Repair, and Overhaulcited by 4
- 2023CARE: A Large Scale CT Image Dataset and Clinical Applicable Benchmark Model for Rectal Cancer Segmentationcited by 4
- 2024MaskSAM: Towards Auto-prompt SAM with Mask Classification for Volumetric Medical Image Segmentationcited by 4
- 2024ProMISe: Promptable Medical Image Segmentation using SAMcited by 3
- 2024PP-SAM: Perturbed Prompts for Robust Adaptation of Segment Anything Model for Polyp Segmentationcited by 3
- 2026Boosting Segment Anything Model to Generalize Visually Non-Salient Scenarioscited by 3
- 2023Segment Anything Model-guided Collaborative Learning Network for Scribble-supervised Polyp Segmentationcited by 2
- 2024TransLandSeg: A Transfer Learning Approach for Landslide Semantic Segmentation Based on Vision Foundation Modelcited by 2
- 2025PolypFlow: Reinforcing Polyp Segmentation with Flow-Driven Dynamicscited by 2
- 2025PG-SAM: Prior-Guided SAM with Medical for Multi-organ Segmentationcited by 2
50 most cited of 64 All 64 (JSON)
- 2026InstEditSeg: Instruction-Driven Image Editing for Polyp and Skin Lesion Segmentation2 Sep 2026
- 2026MedCore: Boundary-Preserving Medical Core Pruning for MedSAM13 May 2026
- 2026BALD-SAM: Disagreement-based Active Prompting in Interactive Segmentation11 Mar 2026
- 2026Axial-Centric Cross-Plane Attention for 3D Medical Image Classification25 Feb 2026
- 2026Towards Any-Quality Image Segmentation via Generative and Adaptive Latent Space Enhancement5 Jan 2026
- 2026Boosting Segment Anything Model to Generalize Visually Non-Salient Scenarios2 Jan 2026
- 2025Encoding Structural Constraints into Segment Anything Models via Probabilistic Graphical Models26 Sep 2025
- 2025SAM-DCE: Addressing Token Uniformity and Semantic Over-Smoothing in Medical Segmentation21 Sep 2025
- 2025MedDINOv3: How to adapt vision foundation models for medical image segmentation?2 Sep 2025
- 2025SAMed-2: Selective Memory Enhanced Medical Segment Anything Model4 Jul 2025
- 2025Recent Advances in Medical Imaging Segmentation: A Survey14 May 2025
- 2025Adapting a Segmentation Foundation Model for Medical Image Classification9 May 2025
38 more
- 2025BiSeg-SAM: Weakly-Supervised Post-Processing Framework for Boosting Binary Segmentation in Segment Anything Models2 Apr 2025
- 2025PG-SAM: Prior-Guided SAM with Medical for Multi-organ Segmentation23 Mar 2025
- 2025PolypFlow: Reinforcing Polyp Segmentation with Flow-Driven Dynamics26 Feb 2025
- 2025Surgical Scene Understanding in the Era of Foundation AI Models: A Comprehensive Review16 Feb 2025
- 2025MedicoSAM: Robust Improvement of SAM for Medical Imaging20 Jan 2025
- 2024SAFIRE: Segment Any Forged Image Region11 Dec 2024
- 2024Interactive Medical Image Segmentation: A Benchmark Dataset and Baseline19 Nov 2024
- 2024Polyp-E: Benchmarking the Robustness of Deep Segmentation Models via Polyp Editing22 Oct 2024
- 2024On Efficient Variants of Segment Anything Model: A Survey7 Oct 2024
- 2024DarkSAM: Fooling Segment Anything Model to Segment Nothing26 Sep 2024
- 2024Self-Prompting Polyp Segmentation in Colonoscopy using Hybrid Yolo-SAM 2 Model14 Sep 2024
- 2024MedSAM-U: Uncertainty-Guided Auto Multi-Prompt Adaptation for Reliable MedSAM2 Sep 2024
- 2024PAM: A Propagation-Based Model for Segmenting Any 3D Objects across Multi-Modal Medical Images25 Aug 2024
- 2024Polyp SAM 2: Advancing Zero shot Polyp Segmentation in Colorectal Cancer Detection12 Aug 2024
- 2024Segment anything model 2: an application to 2D and 3D medical images1 Aug 2024
- 2024Polyp segmentation in colonoscopy images using DeepLabV3++27 Jul 2024
- 2024Urban Waterlogging Detection: A Challenging Benchmark and Large-Small Model Co-Adapter11 Jul 2024
- 2024Boosting Medical Image Classification with Segmentation Foundation Model16 Jun 2024
- 2024PP-SAM: Perturbed Prompts for Robust Adaptation of Segment Anything Model for Polyp Segmentation27 May 2024
- 2024How to build the best medical image segmentation algorithm using foundation models: a comprehensive empirical study with Segment Anything Model15 Apr 2024
- 2024Unleashing the Potential of SAM for Medical Adaptation via Hierarchical Decoding27 Mar 2024
- 2024MaskSAM: Towards Auto-prompt SAM with Mask Classification for Volumetric Medical Image Segmentation21 Mar 2024
- 2024SAMCT: Segment Any CT Allowing Labor-Free Task-Indicator Prompts20 Mar 2024
- 2024TransLandSeg: A Transfer Learning Approach for Landslide Semantic Segmentation Based on Vision Foundation Model15 Mar 2024
- 2024ProMISe: Promptable Medical Image Segmentation using SAM7 Mar 2024
- 2024Polyp-DAM: Polyp segmentation via depth anything model3 Feb 2024
- 2024Foundation Models for Biomedical Image Segmentation: A Survey15 Jan 2024
- 2024Segment Anything Model for Medical Image Segmentation: Current Applications and Future Directions7 Jan 2024
- 2024Data-Centric Foundation Models in Computational Healthcare: A Survey4 Jan 2024
- 2023Segment Anything Model-guided Collaborative Learning Network for Scribble-supervised Polyp Segmentation1 Dec 2023
- 2023A Survey on Deep Learning for Polyp Segmentation: Techniques, Challenges and Future Trends30 Nov 2023
- 2023Deep Interactive Segmentation of Medical Images: A Systematic Review and Taxonomy23 Nov 2023
- 2023EviPrompt: A Training-Free Evidential Prompt Generation Method for Segment Anything Model in Medical Images10 Nov 2023
- 2023Learning the What and How of Annotation in Video Object Segmentation8 Nov 2023
- 2023Text Augmented Spatial-aware Zero-shot Referring Image Segmentation27 Oct 2023
- 2023RetSeg: Retention-based Colorectal Polyps Segmentation Network9 Oct 2023
- 2023Self-Sampling Meta SAM: Enhancing Few-shot Medical Image Segmentation with Meta-Learning31 Aug 2023
- 2023SAM-PARSER: Fine-tuning SAM Efficiently by Parameter Space Reconstruction28 Aug 2023
50 newest of 64 All 64 (JSON)
- 2024Segment Anything Model for Medical Image Segmentation: Current Applications and Future Directionscited by 97
- 2023A Comprehensive Survey on Segment Anything Model for Vision and Beyondcited by 64
- 2024Unleashing the Potential of SAM for Medical Adaptation via Hierarchical Decodingcited by 48
- 2023A Survey on Segment Anything Model (SAM): Vision Foundation Model Meets Prompt Engineeringcited by 45
- 2024How to build the best medical image segmentation algorithm using foundation models: a comprehensive empirical study with Segment Anything Modelcited by 32
- 2024DarkSAM: Fooling Segment Anything Model to Segment Nothingcited by 32
- 2024Interactive Medical Image Segmentation: A Benchmark Dataset and Baselinecited by 30
- 2024Foundation Models for Biomedical Image Segmentation: A Surveycited by 28
- 2024Data-Centric Foundation Models in Computational Healthcare: A Surveycited by 27
- 2024Segment anything model 2: an application to 2D and 3D medical imagescited by 27
- 2023DeSAM: Decoupled Segment Anything Model for Generalizable Medical Image Segmentationcited by 26
- 2023Deep Interactive Segmentation of Medical Images: A Systematic Review and Taxonomycited by 26
12 most cited of 63 All 63 (JSON)
- 2026InstEditSeg: Instruction-Driven Image Editing for Polyp and Skin Lesion Segmentation2 Sep 2026
- 2026MedCore: Boundary-Preserving Medical Core Pruning for MedSAM13 May 2026
- 2026BALD-SAM: Disagreement-based Active Prompting in Interactive Segmentation11 Mar 2026
- 2026Axial-Centric Cross-Plane Attention for 3D Medical Image Classification25 Feb 2026
- 2026Towards Any-Quality Image Segmentation via Generative and Adaptive Latent Space Enhancement5 Jan 2026
- 2026Boosting Segment Anything Model to Generalize Visually Non-Salient Scenarios2 Jan 2026
- 2025Encoding Structural Constraints into Segment Anything Models via Probabilistic Graphical Models26 Sep 2025
- 2025SAM-DCE: Addressing Token Uniformity and Semantic Over-Smoothing in Medical Segmentation21 Sep 2025
- 2025MedDINOv3: How to adapt vision foundation models for medical image segmentation?2 Sep 2025
- 2025SAMed-2: Selective Memory Enhanced Medical Segment Anything Model4 Jul 2025
- 2025Recent Advances in Medical Imaging Segmentation: A Survey14 May 2025
- 2025Adapting a Segmentation Foundation Model for Medical Image Classification9 May 2025
12 newest of 63 All 63 (JSON)