Data-Centric Foundation Models in Computational Healthcare: A Survey
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Abstract (arXiv)
The advent of foundation models (FMs) as an emerging suite of AI techniques has struck a wave of opportunities in computational healthcare. The interactive nature of these models, guided by pre-training data and human instructions, has ignited a data-centric AI paradigm that emphasizes better data characterization, quality, and scale. In healthcare AI, obtaining and processing high-quality clinical data records has been a longstanding challenge, encompassing data quantity, annotation, patient privacy, and ethics. In this survey, we investigate a wide range of data-centric approaches in the FM era (from model pre-training to inference) towards improving the healthcare workflow. We discuss key perspectives in AI security, assessment, and alignment with human values. Finally, we offer a promising outlook on FM-based analytics to enhance patient outcomes and clinical workflows in the evolving landscape of healthcare and medicine. We provide an up-to-date list of healthcare-related foundation models and datasets at https://github.com/Yunkun-Zhang/Data-Centric-FM-Healthcare.
Key facts. Cited by 27 papers in the map (data through 7 Oct 2026). Builds on 174 of its 410 references that are in the map. First posted on arXiv 4 Jan 2024.
Builds on
174 of 410 references.
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50 most cited of 174 All 174 (JSON)
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Citing papers per year: 2024: 9; 2025: 12; 2026: 6.
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- 2024A Comprehensive Survey of Foundation Models in Medicinecited by 56
- 2024A Comprehensive Survey of Large Language Models and Multimodal Large Language Models in Medicinecited by 45
- 2024MedBench: A Comprehensive, Standardized, and Reliable Benchmarking System for Evaluating Chinese Medical Large Language Modelscited by 21
- 2024Has Multimodal Learning Delivered Universal Intelligence in Healthcare? A Comprehensive Surveycited by 20
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- 2024Empowering Cognitive Digital Twins with Generative Foundation Models: Developing a Low-Carbon Integrated Freight Transportation Systemcited by 1
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- 2025Brain Imaging Foundation Models, Are We There Yet? A Systematic Review of Foundation Models for Brain Imaging and Biomedical Researchcited by 0
- 2025ALL-PET: A Low-resource and Low-shot PET Foundation Model in Projection Domaincited by 0
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- 2026Clinical Note Bloat Reduction for Efficient LLM Use21 Mar 2026
- 2026Toward Clinically Ready Foundation Models in Medical Image Analysis: Adaptation Mechanisms and Deployment Trade-offs15 Mar 2026
- 2026Does medical specialization of VLMs enhance discriminative power?: A comprehensive investigation through feature distribution analysis21 Jan 2026
- 2026DExTeR: Weakly Semi-Supervised Object Detection with Class and Instance Experts for Medical Imaging20 Jan 2026
- 2025Anatomy-VLM: A Fine-grained Vision-Language Model for Medical Interpretation11 Nov 2025
- 2025Language-Enhanced Generative Modeling for Amyloid PET Synthesis from MRI and Blood Biomarkers4 Nov 2025
- 2025Think Twice to See More: Iterative Visual Reasoning in Medical VLMs11 Oct 2025
- 2025ALL-PET: A Low-resource and Low-shot PET Foundation Model in Projection Domain11 Sep 2025
- 2025Mediator-Guided Multi-Agent Collaboration among Open-Source Models for Medical Decision-Making8 Aug 2025
- 2025Benchmarking Foundation Models and Parameter-Efficient Fine-Tuning for Prognosis Prediction in Medical Imaging23 Jun 2025
15 more
- 2025Brain Imaging Foundation Models, Are We There Yet? A Systematic Review of Foundation Models for Brain Imaging and Biomedical Research16 Jun 2025
- 2025Towards the Autonomous Optimization of Urban Logistics: Training Generative AI with Scientific Tools via Agentic Digital Twins and Model Context Protocol16 Jun 2025
- 2025Aligning Large Language Models with Healthcare Stakeholders: A Pathway to Trustworthy AI Integration2 May 2025
- 2025Show and Segment: Universal Medical Image Segmentation via In-Context Learning25 Mar 2025
- 2025MedForge: Building Medical Foundation Models Like Open Source Software Development22 Feb 2025
- 2025Surgical Scene Understanding in the Era of Foundation AI Models: A Comprehensive Review16 Feb 2025
- 2024Empowering Cognitive Digital Twins with Generative Foundation Models: Developing a Low-Carbon Integrated Freight Transportation System8 Oct 2024
- 2024Has Multimodal Learning Delivered Universal Intelligence in Healthcare? A Comprehensive Survey23 Aug 2024
- 2024Cost-effective Instruction Learning for Pathology Vision and Language Analysis25 Jul 2024
- 2024MedBench: A Comprehensive, Standardized, and Reliable Benchmarking System for Evaluating Chinese Medical Large Language Models24 Jun 2024
- 2024A Comprehensive Survey of Foundation Models in Medicine15 Jun 2024
- 2024Aligning Human Knowledge with Visual Concepts Towards Explainable Medical Image Classification8 Jun 2024
- 2024A Comprehensive Survey of Large Language Models and Multimodal Large Language Models in Medicine14 May 2024
- 2024PathM3: A Multimodal Multi-Task Multiple Instance Learning Framework for Whole Slide Image Classification and Captioning13 Mar 2024
- 2024OpenMEDLab: An Open-source Platform for Multi-modality Foundation Models in Medicine28 Feb 2024
- 2024A Comprehensive Survey of Large Language Models and Multimodal Large Language Models in Medicinecited by 45
- 2024Cost-effective Instruction Learning for Pathology Vision and Language Analysiscited by 7
- 2025Anatomy-VLM: A Fine-grained Vision-Language Model for Medical Interpretationcited by 3
- 2026Does medical specialization of VLMs enhance discriminative power?: A comprehensive investigation through feature distribution analysiscited by 0
- 2026Does medical specialization of VLMs enhance discriminative power?: A comprehensive investigation through feature distribution analysis21 Jan 2026
- 2025Anatomy-VLM: A Fine-grained Vision-Language Model for Medical Interpretation11 Nov 2025
- 2024Cost-effective Instruction Learning for Pathology Vision and Language Analysis25 Jul 2024
- 2024A Comprehensive Survey of Large Language Models and Multimodal Large Language Models in Medicine14 May 2024
- 2024A Comprehensive Survey of Foundation Models in Medicinecited by 56
- 2024MedBench: A Comprehensive, Standardized, and Reliable Benchmarking System for Evaluating Chinese Medical Large Language Modelscited by 21
- 2024Has Multimodal Learning Delivered Universal Intelligence in Healthcare? A Comprehensive Surveycited by 20
- 2024Aligning Human Knowledge with Visual Concepts Towards Explainable Medical Image Classificationcited by 17
- 2025Show and Segment: Universal Medical Image Segmentation via In-Context Learningcited by 15
- 2024PathM3: A Multimodal Multi-Task Multiple Instance Learning Framework for Whole Slide Image Classification and Captioningcited by 13
- 2025Surgical Scene Understanding in the Era of Foundation AI Models: A Comprehensive Reviewcited by 8
- 2024OpenMEDLab: An Open-source Platform for Multi-modality Foundation Models in Medicinecited by 5
- 2025Benchmarking Foundation Models and Parameter-Efficient Fine-Tuning for Prognosis Prediction in Medical Imagingcited by 3
- 2024Empowering Cognitive Digital Twins with Generative Foundation Models: Developing a Low-Carbon Integrated Freight Transportation Systemcited by 1
- 2025MedForge: Building Medical Foundation Models Like Open Source Software Developmentcited by 1
- 2025Language-Enhanced Generative Modeling for Amyloid PET Synthesis from MRI and Blood Biomarkerscited by 1
12 most cited of 17 All 17 (JSON)
- 2026Clinical Note Bloat Reduction for Efficient LLM Use21 Mar 2026
- 2026Toward Clinically Ready Foundation Models in Medical Image Analysis: Adaptation Mechanisms and Deployment Trade-offs15 Mar 2026
- 2026DExTeR: Weakly Semi-Supervised Object Detection with Class and Instance Experts for Medical Imaging20 Jan 2026
- 2025Language-Enhanced Generative Modeling for Amyloid PET Synthesis from MRI and Blood Biomarkers4 Nov 2025
- 2025ALL-PET: A Low-resource and Low-shot PET Foundation Model in Projection Domain11 Sep 2025
- 2025Benchmarking Foundation Models and Parameter-Efficient Fine-Tuning for Prognosis Prediction in Medical Imaging23 Jun 2025
- 2025Brain Imaging Foundation Models, Are We There Yet? A Systematic Review of Foundation Models for Brain Imaging and Biomedical Research16 Jun 2025
- 2025Show and Segment: Universal Medical Image Segmentation via In-Context Learning25 Mar 2025
- 2025MedForge: Building Medical Foundation Models Like Open Source Software Development22 Feb 2025
- 2025Surgical Scene Understanding in the Era of Foundation AI Models: A Comprehensive Review16 Feb 2025
- 2024Empowering Cognitive Digital Twins with Generative Foundation Models: Developing a Low-Carbon Integrated Freight Transportation System8 Oct 2024
- 2024Has Multimodal Learning Delivered Universal Intelligence in Healthcare? A Comprehensive Survey23 Aug 2024
12 newest of 17 All 17 (JSON)