mlsanityData to 7 Oct 2026

MultiResUNet : Rethinking the U-Net Architecture for Multimodal Biomedical Image Segmentation

arXiv 1902.04049 ↗First posted 11 Feb 2019cs.CVcited by 195

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Abstract (arXiv)

In recent years Deep Learning has brought about a breakthrough in Medical Image Segmentation. U-Net is the most prominent deep network in this regard, which has been the most popular architecture in the medical imaging community. Despite outstanding overall performance in segmenting multimodal medical images, from extensive experimentations on challenging datasets, we found out that the classical U-Net architecture seems to be lacking in certain aspects. Therefore, we propose some modifications to improve upon the already state-of-the-art U-Net model. Hence, following the modifications we develop a novel architecture MultiResUNet as the potential successor to the successful U-Net architecture. We have compared our proposed architecture MultiResUNet with the classical U-Net on a vast repertoire of multimodal medical images. Albeit slight improvements in the cases of ideal images, a remarkable gain in performance has been attained for challenging images. We have evaluated our model on five different datasets, each with their own unique challenges, and have obtained a relative improvement in performance of 10.15%, 5.07%, 2.63%, 1.41%, and 0.62% respectively.

Key facts. Cited by 195 papers in the map (data through 7 Oct 2026). First posted on arXiv 11 Feb 2019.

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2021: 39; 2022: 34; 2023: 46; 2024: 38; 2025: 22; 2026: 16.

195 papers.

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  1. 2021UCTransNet: Rethinking the Skip Connections in U-Net from a Channel-wise Perspective with Transformercited by 197
  2. 2022Medical Image Segmentation Review: The success of U-Netcited by 190
  3. 2024Mamba-UNet: UNet-Like Pure Visual Mamba for Medical Image Segmentationcited by 133
  4. 2022Attention Attention Everywhere: Monocular Depth Prediction with Skip Attentioncited by 92
  5. 2021TransMed: Transformers Advance Multi-modal Medical Image Classificationcited by 85
  6. 2021Knowledge distillation from multi-modal to mono-modal segmentation networkscited by 68
  7. 2021MSRF-Net: A Multi-Scale Residual Fusion Network for Biomedical Image Segmentationcited by 53
  8. 2021A Comprehensive Study on Colorectal Polyp Segmentation with ResUNet++, Conditional Random Field and Test-Time Augmentationcited by 41
  9. 2021FANet: A Feedback Attention Network for Improved Biomedical Image Segmentationcited by 36
  10. 2022ColonFormer: An Efficient Transformer based Method for Colon Polyp Segmentationcited by 28
  11. 2022Assessing generalisability of deep learning-based polyp detection and segmentation methods through a computer vision challengecited by 27
  12. 2023A Unified Framework for U-Net Design and Analysiscited by 27
38 more
  1. 2023ACC-UNet: A Completely Convolutional UNet model for the 2020scited by 26
  2. 2023Source-Free Domain Adaptive Fundus Image Segmentation with Class-Balanced Mean Teachercited by 21
  3. 2021Focus U-Net: A novel dual attention-gated CNN for polyp segmentation during colonoscopycited by 20
  4. 2021Modality specific U-Net variants for biomedical image segmentation: A surveycited by 20
  5. 2024Semi-Mamba-UNet: Pixel-Level Contrastive and Pixel-Level Cross-Supervised Visual Mamba-based UNet for Semi-Supervised Medical Image Segmentationcited by 20
  6. 2023Retinal Vessel Segmentation via a Multi-resolution Contextual Network and Adversarial Learningcited by 19
  7. 2024Pick of the Bunch: Detecting Infrared Small Targets Beyond Hit-Miss Trade-Offs via Selective Rank-Aware Attentioncited by 17
  8. 2021Leveraging Image Complexity in Macro-Level Neural Network Design for Medical Image Segmentationcited by 16
  9. 2023DA-TransUNet: Integrating Spatial and Channel Dual Attention with Transformer U-Net for Medical Image Segmentationcited by 16
  10. 2023E2ENet: Dynamic Sparse Feature Fusion for Accurate and Efficient 3D Medical Image Segmentationcited by 16
  11. 2021LensID: A CNN-RNN-Based Framework Towards Lens Irregularity Detection in Cataract Surgery Videoscited by 15
  12. 2023Dual Cross-Attention for Medical Image Segmentationcited by 15
  13. 2022When CNN Meet with ViT: Towards Semi-Supervised Learning for Multi-Class Medical Image Semantic Segmentationcited by 13
  14. 2022MKIS-Net: A Light-Weight Multi-Kernel Network for Medical Image Segmentationcited by 13
  15. 2024SegStitch: Multidimensional Transformer for Robust and Efficient Medical Imaging Segmentationcited by 13
  16. 2021Sharp U-Net: Depthwise Convolutional Network for Biomedical Image Segmentationcited by 12
  17. 2024Rotate to Scan: UNet-like Mamba with Triplet SSM Module for Medical Image Segmentationcited by 12
  18. 2021CFPNet-M: A Light-Weight Encoder-Decoder Based Network for Multimodal Biomedical Image Real-Time Segmentationcited by 11
  19. 2021GMSRF-Net: An improved generalizability with global multi-scale residual fusion network for polyp segmentationcited by 11
  20. 2022R2U++: A Multiscale Recurrent Residual U-Net with Dense Skip Connections for Medical Image Segmentationcited by 11
  21. 2023Enhancing Medical Image Segmentation with TransCeption: A Multi-Scale Feature Fusion Approachcited by 11
  22. 2021Predicting Mechanically Driven Full-Field Quantities of Interest with Deep Learning-Based Metamodelscited by 10
  23. 2022MFSNet: A Multi Focus Segmentation Network for Skin Lesion Segmentationcited by 10
  24. 2022ScaleFormer: Revisiting the Transformer-based Backbones from a Scale-wise Perspective for Medical Image Segmentationcited by 10
  25. 2023Deep Learning in Breast Cancer Imaging: A Decade of Progress and Future Directionscited by 10
  26. 2023Feature Enhancer Segmentation Network (FES-Net) for Vessel Segmentationcited by 10
  27. 2024Multimodal Data Integration for Precision Oncology: Challenges and Future Directionscited by 10
  28. 2025A Comprehensive Review of U-Net and Its Variants: Advances and Applications in Medical Image Segmentationcited by 10
  29. 20213D AGSE-VNet: An Automatic Brain Tumor MRI Data Segmentation Frameworkcited by 9
  30. 2021ReCal-Net: Joint Region-Channel-Wise Calibrated Network for Semantic Segmentation in Cataract Surgery Videoscited by 8
  31. 2021A singular Riemannian geometry approach to Deep Neural Networks II. Reconstruction of 1-D equivalence classescited by 8
  32. 2023MaxViT-UNet: Multi-Axis Attention for Medical Image Segmentationcited by 8
  33. 2024Integrating Mamba Sequence Model and Hierarchical Upsampling Network for Accurate Semantic Segmentation of Multiple Sclerosis Legioncited by 8
  34. 2021Effects of Image Size on Deep Learningcited by 7
  35. 2021EDITH :ECG biometrics aided by Deep learning for reliable Individual auTHenticationcited by 7
  36. 2022Meta Ordinal Regression Forest for Medical Image Classification with Ordinal Labelscited by 7
  37. 2022DeepPyramid: Enabling Pyramid View and Deformable Pyramid Reception for Semantic Segmentation in Cataract Surgery Videoscited by 7
  38. 2022Swinv2-Imagen: Hierarchical Vision Transformer Diffusion Models for Text-to-Image Generationcited by 7

50 most cited of 195 All 195 (JSON)