mlsanityData to 7 Oct 2026

UCTransNet: Rethinking the Skip Connections in U-Net from a Channel-wise Perspective with Transformer

arXiv 2109.04335 ↗First posted 9 Sep 2021cs.CV cs.LG eess.IVcited by 197

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Abstract (arXiv)

Most recent semantic segmentation methods adopt a U-Net framework with an encoder-decoder architecture. It is still challenging for U-Net with a simple skip connection scheme to model the global multi-scale context: 1) Not each skip connection setting is effective due to the issue of incompatible feature sets of encoder and decoder stage, even some skip connection negatively influence the segmentation performance; 2) The original U-Net is worse than the one without any skip connection on some datasets. Based on our findings, we propose a new segmentation framework, named UCTransNet (with a proposed CTrans module in U-Net), from the channel perspective with attention mechanism. Specifically, the CTrans module is an alternate of the U-Net skip connections, which consists of a sub-module to conduct the multi-scale Channel Cross fusion with Transformer (named CCT) and a sub-module Channel-wise Cross-Attention (named CCA) to guide the fused multi-scale channel-wise information to effectively connect to the decoder features for eliminating the ambiguity. Hence, the proposed connection consisting of the CCT and CCA is able to replace the original skip connection to solve the semantic gaps for an accurate automatic medical image segmentation. The experimental results suggest that our UCTransNet produces more precise segmentation performance and achieves consistent improvements over the state-of-the-art for semantic segmentation across different datasets and conventional architectures involving transformer or U-shaped framework. Code: https://github.com/McGregorWwww/UCTransNet.

Key facts. Cited by 197 papers in the map (data through 7 Oct 2026). Builds on 28 of its 33 references that are in the map. First posted on arXiv 9 Sep 2021.

Builds on

28 of 33 references.

References · 28

  1. 2015Deep Residual Learning for Image Recognitioncited by 51,809
  2. 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 29,915
  3. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
  4. 2021Swin Transformer: Hierarchical Vision Transformer using Shifted Windowscited by 12,082
  5. 2016Densely Connected Convolutional Networkscited by 6,691
  6. 2014Fully Convolutional Networks for Semantic Segmentationcited by 4,845
  7. 2016V-Net: Fully Convolutional Neural Networks for Volumetric Medical Image Segmentationcited by 2,284
  8. 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,552
  9. 2018UNet++: A Nested U-Net Architecture for Medical Image Segmentationcited by 1,518
  10. 2018Attention U-Net: Learning Where to Look for the Pancreascited by 1,420
  11. 2020Rethinking Semantic Segmentation from a Sequence-to-Sequence Perspective with Transformerscited by 1,368
  12. 2021Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentationcited by 1,218
16 more
  1. 2016Instance Normalization: The Missing Ingredient for Fast Stylizationcited by 1,187
  2. 2021UNETR: Transformers for 3D Medical Image Segmentationcited by 954
  3. 2019ECA-Net: Efficient Channel Attention for Deep Convolutional Neural Networkscited by 572
  4. 2020UNet 3+: A Full-Scale Connected UNet for Medical Image Segmentationcited by 331
  5. 2021Medical Transformer: Gated Axial-Attention for Medical Image Segmentationcited by 319
  6. 2021TransFuse: Fusing Transformers and CNNs for Medical Image Segmentationcited by 258
  7. 2016Gland Segmentation in Colon Histology Images: The GlaS Challenge Contestcited by 203
  8. 2019MultiResUNet : Rethinking the U-Net Architecture for Multimodal Biomedical Image Segmentationcited by 195
  9. 2018Recurrent Residual Convolutional Neural Network based on U-Net (R2U-Net) for Medical Image Segmentationcited by 180
  10. 2016The Importance of Skip Connections in Biomedical Image Segmentationcited by 126
  11. 2021UTNet: A Hybrid Transformer Architecture for Medical Image Segmentationcited by 116
  12. 2020Domain Adaptive Relational Reasoning for 3D Multi-Organ Segmentationcited by 48
  13. 2021Multi-Compound Transformer for Accurate Biomedical Image Segmentationcited by 42
  14. 2021Instance-based Vision Transformer for Subtyping of Papillary Renal Cell Carcinoma in Histopathological Imagecited by 22
  15. 2021A Multi-Branch Hybrid Transformer Networkfor Corneal Endothelial Cell Segmentationcited by 18
  16. 2019Segmenting Medical MRI via Recurrent Decoding Cellcited by 3

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2021: 1; 2022: 13; 2023: 48; 2024: 68; 2025: 43; 2026: 24.

197 papers.

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  1. 2024VM-UNet: Vision Mamba UNet for Medical Image Segmentationcited by 286
  2. 2022Transformers in Medical Imaging: A Surveycited by 245
  3. 2022Medical Image Segmentation Review: The success of U-Netcited by 190
  4. 2021U-shape Transformer for Underwater Image Enhancementcited by 110
  5. 2022LViT: Language meets Vision Transformer in Medical Image Segmentationcited by 110
  6. 2023AutoSAM: Adapting SAM to Medical Images by Overloading the Prompt Encodercited by 70
  7. 2024EMCAD: Efficient Multi-scale Convolutional Attention Decoding for Medical Image Segmentationcited by 64
  8. 2024SCTransNet: Spatial-channel Cross Transformer Network for Infrared Small Target Detectioncited by 60
  9. 2023Computer-Vision Benchmark Segment-Anything Model (SAM) in Medical Images: Accuracy in 12 Datasetscited by 45
  10. 2022DCSAU-Net: A Deeper and More Compact Split-Attention U-Net for Medical Image Segmentationcited by 37
  11. 2024AllSpark: Reborn Labeled Features from Unlabeled in Transformer for Semi-Supervised Semantic Segmentationcited by 35
  12. 2024Touchstone Benchmark: Are We on the Right Way for Evaluating AI Algorithms for Medical Segmentation?cited by 31
38 more
  1. 2024Cross-Modal Conditioned Reconstruction for Language-guided Medical Image Segmentationcited by 27
  2. 2023ACC-UNet: A Completely Convolutional UNet model for the 2020scited by 26
  3. 2024Segment Any Cell: A SAM-based Auto-prompting Fine-tuning Framework for Nuclei Segmentationcited by 24
  4. 2022DuAT: Dual-Aggregation Transformer Network for Medical Image Segmentationcited by 22
  5. 2023G-CASCADE: Efficient Cascaded Graph Convolutional Decoding for 2D Medical Image Segmentationcited by 21
  6. 2024SelfReg-UNet: Self-Regularized UNet for Medical Image Segmentationcited by 18
  7. 2024SDR-Former: A Siamese Dual-Resolution Transformer for Liver Lesion Classification Using 3D Multi-Phase Imagingcited by 17
  8. 2024U-Nets as Belief Propagation: Efficient Classification, Denoising, and Diffusion in Generative Hierarchical Modelscited by 17
  9. 2023DA-TransUNet: Integrating Spatial and Channel Dual Attention with Transformer U-Net for Medical Image Segmentationcited by 16
  10. 2023E2ENet: Dynamic Sparse Feature Fusion for Accurate and Efficient 3D Medical Image Segmentationcited by 16
  11. 2022Online Easy Example Mining for Weakly-supervised Gland Segmentation from Histology Imagescited by 15
  12. 2023Dual Cross-Attention for Medical Image Segmentationcited by 15
  13. 2025CausalCLIPSeg: Unlocking CLIP's Potential in Referring Medical Image Segmentation with Causal Interventioncited by 15
  14. 2023DermoSegDiff: A Boundary-aware Segmentation Diffusion Model for Skin Lesion Delineationcited by 12
  15. 2023Masked Diffusion as Self-supervised Representation Learnercited by 11
  16. 2023Semi-supervised Segmentation of Histopathology Images with Noise-Aware Topological Consistencycited by 11
  17. 2022ScaleFormer: Revisiting the Transformer-based Backbones from a Scale-wise Perspective for Medical Image Segmentationcited by 10
  18. 2023Deep Learning in Breast Cancer Imaging: A Decade of Progress and Future Directionscited by 10
  19. 2023Residual Spatial Fusion Network for RGB-Thermal Semantic Segmentationcited by 10
  20. 2024HySparK: Hybrid Sparse Masking for Large Scale Medical Image Pre-Trainingcited by 10
  21. 2025DCFormer: Efficient 3D Vision-Language Modeling with Decomposed Convolutionscited by 10
  22. 2025A Comprehensive Review of U-Net and Its Variants: Advances and Applications in Medical Image Segmentationcited by 10
  23. 2022Recent Progress in Transformer-based Medical Image Analysiscited by 9
  24. 2023Attention Mechanisms in Medical Image Segmentation: A Surveycited by 9
  25. 2023ESDMR-Net: A Lightweight Network With Expand-Squeeze and Dual Multiscale Residual Connections for Medical Image Segmentationcited by 9
  26. 2023Narrowing the semantic gaps in U-Net with learnable skip connections: The case of medical image segmentationcited by 9
  27. 2024Advancing Medical Image Segmentation with Mini-Net: A Lightweight Solution Tailored for Efficient Segmentation of Medical Imagescited by 9
  28. 2022MEW-UNet: Multi-axis representation learning in frequency domain for medical image segmentationcited by 8
  29. 2023Towards Simultaneous Segmentation of Liver Tumors and Intrahepatic Vessels via Cross-attention Mechanismcited by 8
  30. 2023MaxViT-UNet: Multi-Axis Attention for Medical Image Segmentationcited by 8
  31. 2024DSCA: A Digital Subtraction Angiography Sequence Dataset and Spatio-Temporal Model for Cerebral Artery Segmentationcited by 8
  32. 2023Coarse-to-Fine Covid-19 Segmentation via Vision-Language Alignmentcited by 7
  33. 2025RWKV-UNet: Improving UNet with Long-Range Cooperation for Effective Medical Image Segmentationcited by 7
  34. 2025Deep learning based infrared small object segmentation: Challenges and future directionscited by 7
  35. 2025Pre-Trained LLM is a Semantic-Aware and Generalizable Segmentation Boostercited by 7
  36. 2023U-Netmer: U-Net meets Transformer for medical image segmentationcited by 6
  37. 2023SA2-Net: Scale-aware Attention Network for Microscopic Image Segmentationcited by 6
  38. 2024Generative Medical Segmentationcited by 6

50 most cited of 197 All 197 (JSON)