Noise2Void - Learning Denoising from Single Noisy Images
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Cited by 26 in Diffusion models, but placed by its own abstract, which didn’t fit.
Abstract (arXiv)
The field of image denoising is currently dominated by discriminative deep learning methods that are trained on pairs of noisy input and clean target images. Recently it has been shown that such methods can also be trained without clean targets. Instead, independent pairs of noisy images can be used, in an approach known as Noise2Noise (N2N). Here, we introduce Noise2Void (N2V), a training scheme that takes this idea one step further. It does not require noisy image pairs, nor clean target images. Consequently, N2V allows us to train directly on the body of data to be denoised and can therefore be applied when other methods cannot. Especially interesting is the application to biomedical image data, where the acquisition of training targets, clean or noisy, is frequently not possible. We compare the performance of N2V to approaches that have either clean target images and/or noisy image pairs available. Intuitively, N2V cannot be expected to outperform methods that have more information available during training. Still, we observe that the denoising performance of Noise2Void drops in moderation and compares favorably to training-free denoising methods.
Key facts. Cited by 364 papers in the map (data through 14 Oct 2026). First posted on arXiv 27 Nov 2018.
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Citing papers per year: 2020: 1; 2021: 46; 2022: 58; 2023: 75; 2024: 59; 2025: 62; 2026: 63.
364 papers.
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- 2021NeRF in the Dark: High Dynamic Range View Synthesis from Noisy Raw Imagescited by 336
- 2021Self-Supervised Learning of Graph Neural Networks: A Unified Reviewcited by 184
- 2024A Survey on Diffusion Models for Inverse Problemscited by 180
- 2021Neighbor2Neighbor: Self-Supervised Denoising from Single Noisy Imagescited by 173
- 2021Noise2Score: Tweedie's Approach to Self-Supervised Image Denoising without Clean Imagescited by 113
- 2023Ambient Diffusion: Learning Clean Distributions from Corrupted Datacited by 111
- 2022AP-BSN: Self-Supervised Denoising for Real-World Images via Asymmetric PD and Blind-Spot Networkcited by 93
- 2022Practical Blind Image Denoising via Swin-Conv-UNet and Data Synthesiscited by 86
- 2022Blind2Unblind: Self-Supervised Image Denoising with Visible Blind Spotscited by 84
- 2021Equivariant Imaging: Learning Beyond the Range Spacecited by 83
- 2021Self-supervised learning methods and applications in medical imaging analysis: A surveycited by 77
- 2023Image Denoising: The Deep Learning Revolution and Beyond -- A Survey Paper --cited by 71
38 more
- 2021Physics-based Noise Modeling for Extreme Low-light Photographycited by 67
- 2022MR Image Denoising and Super-Resolution Using Regularized Reverse Diffusioncited by 67
- 2023Zero-Shot Noise2Noise: Efficient Image Denoising without any Datacited by 61
- 2023Masked Image Training for Generalizable Deep Image Denoisingcited by 57
- 2022C2N: Practical Generative Noise Modeling for Real-World Denoisingcited by 56
- 2023DDM2: Self-Supervised Diffusion MRI Denoising with Generative Diffusion Modelscited by 51
- 2022Dancing under the stars: video denoising in starlightcited by 47
- 2023Neural Degradation Representation Learning for All-In-One Image Restorationcited by 46
- 2022CVF-SID: Cyclic multi-Variate Function for Self-Supervised Image Denoising by Disentangling Noise from Imagecited by 45
- 2024Consistent Diffusion Meets Tweedie: Training Exact Ambient Diffusion Models with Noisy Datacited by 44
- 2023LG-BPN: Local and Global Blind-Patch Network for Self-Supervised Real-World Denoisingcited by 37
- 2021IDR: Self-Supervised Image Denoising via Iterative Data Refinementcited by 36
- 2023Spatially Adaptive Self-Supervised Learning for Real-World Image Denoisingcited by 33
- 2023On the Posterior Distribution in Denoising: Application to Uncertainty Quantificationcited by 33
- 2024Ambient Diffusion Posterior Sampling: Solving Inverse Problems with Diffusion Models Trained on Corrupted Datacited by 32
- 2023Random Sub-Samples Generation for Self-Supervised Real Image Denoisingcited by 31
- 2021DeFlow: Learning Complex Image Degradations from Unpaired Data with Conditional Flowscited by 30
- 2022A theoretical framework for self-supervised MR image reconstruction using sub-sampling via variable density Noisier2Noisecited by 30
- 2023MM-BSN: Self-Supervised Image Denoising for Real-World with Multi-Mask based on Blind-Spot Networkcited by 30
- 2020Patch2Self: Denoising Diffusion MRI with Self-Supervised Learningcited by 29
- 2023Unsupervised Image Denoising in Real-World Scenarios via Self-Collaboration Parallel Generative Adversarial Branchescited by 29
- 2024Transfer CLIP for Generalizable Image Denoisingcited by 29
- 2021Interpretable Unsupervised Diversity Denoising and Artefact Removalcited by 26
- 2021Optimal Transport for Unsupervised Denoising Learningcited by 24
- 2021FBI-Denoiser: Fast Blind Image Denoiser for Poisson-Gaussian Noisecited by 22
- 2023A Survey on the Robustness of Computer Vision Models against Common Corruptionscited by 21
- 2023From Denoising Training to Test-Time Adaptation: Enhancing Domain Generalization for Medical Image Segmentationcited by 20
- 2023DarkVisionNet: Low-Light Imaging via RGB-NIR Fusion with Deep Inconsistency Priorcited by 19
- 2021Noise Distribution Adaptive Self-Supervised Image Denoising using Tweedie Distribution and Score Matchingcited by 18
- 2022Learn from Unpaired Data for Image Restoration: A Variational Bayes Approachcited by 18
- 2024How much is a noisy image worth? Data Scaling Laws for Ambient Diffusioncited by 18
- 2021Unsupervised Deep Learning Methods for Biological Image Reconstruction and Enhancementcited by 17
- 2022Noise2NoiseFlow: Realistic Camera Noise Modeling without Clean Imagescited by 17
- 2022Self-Supervised Image Restoration with Blurry and Noisy Pairscited by 17
- 2023Exploring Efficient Asymmetric Blind-Spots for Self-Supervised Denoising in Real-World Scenarioscited by 17
- 2023Stimulating Diffusion Model for Image Denoising via Adaptive Embedding and Ensemblingcited by 17
- 2023Unleashing the Power of Self-Supervised Image Denoising: A Comprehensive Reviewcited by 17
- 2023Test-Time Degradation Adaptation for Open-Set Image Restorationcited by 17
50 most cited of 364 All 364 (JSON)
- 2026Denoise X: Self-Supervised U-Net for Quantum Mottle Suppression in Chest Radiography13 Oct 2026
- 2026S3-PnP: Plug-and-Play Denoising for Scientific Imaging with Self-Supervised Score Priors13 Oct 2026
- 2026Noise2Match: Self-Supervised Low-Dose CT Denoising via Adaptive Inter-Slice Matching13 Oct 2026
- 2026CellSplat4D: PSF-Aware 4D Gaussian Splatting for Sparse Robotic Live-Cell Imaging3 Oct 2026
- 2026Mask2Restore: Self-Supervised Ultrasound Despeckling via Inpainting26 Sep 2026
- 2026Beyond MSE: Rician Likelihood Denoising for Self-Supervised Cardiac T2 and T1ρ MRI24 Sep 2026
- 2026A Study of the Limits of Collaborative DCT-Based Image Denoising via Interpretable Neural Networks24 Sep 2026
- 2026One-Step Is Optimal: Unconditional Rectified Flows are Noise2Noise Denoisers, and Multi-Step Integration Provably Hurts---A Benchmark and Task-Based Detectability Study on Low-Dose CT15 Sep 2026
- 2026Noise2Noise Revisited: Training Pair Distributions Dominate Loss Choice in Self-Supervised Denoising15 Sep 2026
- 2026NOVA-GS: Noise-Aware View-Consistent Gaussian Splatting for Low-Light Novel View Synthesis11 Sep 2026
- 2026Physics-Driven Independent Pair Generation for Iterative Self-Supervised Low-Dose CT Denoising1 Sep 2026
- 2026Diffusion Based Unpaired Data Learning for Inverse Problems1 Sep 2026
38 more
- 2026Null-Space Diffusion Restoration with Adaptive Uncertainty-Guided Fusion for Ultrasound Speckle Reduction30 Aug 2026
- 2026Physics-Unrolled Neural Operator for Wireless Field Modeling19 Aug 2026
- 2026Closed-Form Nonlocal Shrinkage for Multiplicative Image Denoising and SAR Despeckling15 Aug 2026
- 2026Noise-Robust Conditional Flow Matching: Generating Clean Samples from Noisy Datasets28 Jul 2026
- 2026Why Low-Light Cameras Go Color Blind: Removing Color Bias in Raw Denoising13 Jul 2026
- 2026Design Choices in Splitting-Based Self-Supervised Sparse-View CT Reconstruction12 Jul 2026
- 2026Self-Supervised Test-Time Tuning for Packet Loss Concealment2 Jul 2026
- 2026A Zero-Shot Deep Image Prior Framework for Denoising and Deconvolution in Fluorescence Microscopy26 Jun 2026
- 2026BiDeMem: Bidirectional Degradation Memory for Explainable Image Restoration26 Jun 2026
- 2026Denoising ICF Images with Multiplicative Uniform Noise: A Self-Supervised Study Based on the Log-Domain Noisier2Inverse Framework26 Jun 2026
- 2026Enabling self-supervised learned primal dual with Noise2Inverse25 Jun 2026
- 2026Improving Richardson--Lucy Deconvolution with Diffusion Priors for Fluorescence Microscopy24 Jun 2026
- 2026NGPS: Structure-Preserving Self-Supervised Denoising via Neighbor-Guided Patch Sampling22 Jun 2026
- 2026Poisson2Gaussian: Noise Gaussianization to Enhance Image Denoising22 Jun 2026
- 2026CRIS: Cross-Plane Self-Supervised Isotropic Restoration for Anisotropic Volumetric Imaging Across Modalities14 Jun 2026
- 2026A Deep Learning Iterative Framework for Sentinel-1 Stripmap Enhancement Based on Azimuth Doppler Decomposition27 May 2026
- 2026Internally Referenced Low-Light Enhancement27 May 2026
- 2026CoilDrop-MRI: Self-supervised physics-guided MRI reconstruction with coil dropout26 May 2026
- 2026SIMPC: Learning Self-Induced Mirror-Point Consistency for Unsupervised Point Cloud Denoising26 May 2026
- 2026Physics-Guided Self-Supervised Statistical Residual Learning for Sonar Despeckling with Improved Generalization23 May 2026
- 2026Physen-Noise2Noise: Physics-Guided Self-Supervised Defocus Deblurring with Bias Correction under Low-Light Conditions23 May 2026
- 2026ImPartial: Multi-channel Whole-Cell Segmentation using Partial Annotations22 May 2026
- 2026A Mixture Autoregressive Image Generative Model on Quadtree Regions for Gaussian Noise Removal via Variational Bayes and Gradient Methods12 May 2026
- 2026Deploying Self-Supervised Learning for Real Seismic Data Denoising11 May 2026
- 2026Enabling Unsupervised Training of Deep EEG Denoisers With Intelligent Partitioning7 May 2026
- 2026Learning-based Statistical Refinement for Denoising5 May 2026
- 2026Contrastive Image-Metadata Pre-Training for Materials Transmission Electron Microscopy27 Apr 2026
- 2026Score-Based Matching with Target Guidance for Cryo-EM Denoising20 Apr 2026
- 2026RelativeFlow: Taming Medical Image Denoising Learning with Noisy Reference16 Apr 2026
- 2026Beyond Model Design: Data-Centric Training and Self-Ensemble for Gaussian Color Image Denoising13 Apr 2026
- 2026MatRes: Zero-Shot Test-Time Model Adaptation for Simultaneous Matching and Restoration11 Apr 2026
- 2026SCoRe: Clean Image Generation from Diffusion Models Trained on Noisy Images10 Apr 2026
- 2026Enhanced Self-Supervised Multi-Image Super-Resolution for Camera Array Images8 Apr 2026
- 2026A Mixture of Experts Foundation Model for Scanning Electron Microscopy Image Analysis7 Apr 2026
- 2026TM-BSN: Triangular-Masked Blind-Spot Network for Real-World Self-Supervised Image Denoising6 Apr 2026
- 2026Beyond Fixed Inference: Quantitative Flow Matching for Adaptive Image Denoising2 Apr 2026
- 2026Learning to Recorrupt: Noise Distribution Agnostic Self-Supervised Image Denoising26 Mar 2026
- 2026λSplit: Self-Supervised Content-Aware Spectral Unmixing for Fluorescence Microscopy24 Mar 2026
50 newest of 364 All 364 (JSON)
- 2024A Survey on Diffusion Models for Inverse Problemscited by 180
- 2023DDM2: Self-Supervised Diffusion MRI Denoising with Generative Diffusion Modelscited by 51
- 2024Consistent Diffusion Meets Tweedie: Training Exact Ambient Diffusion Models with Noisy Datacited by 44
- 2023On the Posterior Distribution in Denoising: Application to Uncertainty Quantificationcited by 33
- 2024Ambient Diffusion Posterior Sampling: Solving Inverse Problems with Diffusion Models Trained on Corrupted Datacited by 32
- 2020Patch2Self: Denoising Diffusion MRI with Self-Supervised Learningcited by 29
- 2023Stimulating Diffusion Model for Image Denoising via Adaptive Embedding and Ensemblingcited by 17
- 2024Denoising as Adaptation: Noise-Space Domain Adaptation for Image Restorationcited by 9
- 2024Zero-Shot Adaptation for Approximate Posterior Sampling of Diffusion Models in Inverse Problemscited by 9
- 2023Reconstruct-and-Generate Diffusion Model for Detail-Preserving Image Denoisingcited by 6
- 2025Prompt-SID: Learning Structural Representation Prompt via Latent Diffusion for Single-Image Denoisingcited by 5
- 2025Inverse Flow and Consistency Modelscited by 5
12 most cited of 26 All 26 (JSON)
- 2026Noise-Robust Conditional Flow Matching: Generating Clean Samples from Noisy Datasets28 Jul 2026
- 2026Improving Richardson--Lucy Deconvolution with Diffusion Priors for Fluorescence Microscopy24 Jun 2026
- 2026RelativeFlow: Taming Medical Image Denoising Learning with Noisy Reference16 Apr 2026
- 2026SCoRe: Clean Image Generation from Diffusion Models Trained on Noisy Images10 Apr 2026
- 2026Beyond Fixed Inference: Quantitative Flow Matching for Adaptive Image Denoising2 Apr 2026
- 2026DECADE: A Temporally-Consistent Unsupervised Diffusion Model for Enhanced Rb-82 Dynamic Cardiac PET Image Denoising8 Mar 2026
- 2025CARD: Correlation Aware Restoration with Diffusion4 Dec 2025
- 2025Equivariant Sampling for Improving Diffusion Model-based Image Restoration13 Nov 2025
- 2025Blind-Spot Guided Diffusion for Self-supervised Real-World Denoising19 Sep 2025
- 2025GARD: Gamma-based Anatomical Restoration and Denoising for Retinal OCT12 Sep 2025
- 2025HazeMatching: Dehazing Light Microscopy Images with Guided Conditional Flow Matching27 Jun 2025
- 2025DiffDenoise: Self-Supervised Medical Image Denoising with Conditional Diffusion Models31 Mar 2025
12 newest of 26 All 26 (JSON)
- 2021NeRF in the Dark: High Dynamic Range View Synthesis from Noisy Raw Imagescited by 336
- 2021Self-Supervised Learning of Graph Neural Networks: A Unified Reviewcited by 184
- 2021Neighbor2Neighbor: Self-Supervised Denoising from Single Noisy Imagescited by 173
- 2021Noise2Score: Tweedie's Approach to Self-Supervised Image Denoising without Clean Imagescited by 113
- 2023Ambient Diffusion: Learning Clean Distributions from Corrupted Datacited by 111
- 2022AP-BSN: Self-Supervised Denoising for Real-World Images via Asymmetric PD and Blind-Spot Networkcited by 93
- 2022Practical Blind Image Denoising via Swin-Conv-UNet and Data Synthesiscited by 86
- 2022Blind2Unblind: Self-Supervised Image Denoising with Visible Blind Spotscited by 84
- 2021Equivariant Imaging: Learning Beyond the Range Spacecited by 83
- 2021Self-supervised learning methods and applications in medical imaging analysis: A surveycited by 77
- 2023Image Denoising: The Deep Learning Revolution and Beyond -- A Survey Paper --cited by 71
- 2021Physics-based Noise Modeling for Extreme Low-light Photographycited by 67
12 most cited of 338 All 338 (JSON)
- 2026Denoise X: Self-Supervised U-Net for Quantum Mottle Suppression in Chest Radiography13 Oct 2026
- 2026S3-PnP: Plug-and-Play Denoising for Scientific Imaging with Self-Supervised Score Priors13 Oct 2026
- 2026Noise2Match: Self-Supervised Low-Dose CT Denoising via Adaptive Inter-Slice Matching13 Oct 2026
- 2026CellSplat4D: PSF-Aware 4D Gaussian Splatting for Sparse Robotic Live-Cell Imaging3 Oct 2026
- 2026Mask2Restore: Self-Supervised Ultrasound Despeckling via Inpainting26 Sep 2026
- 2026Beyond MSE: Rician Likelihood Denoising for Self-Supervised Cardiac T2 and T1ρ MRI24 Sep 2026
- 2026A Study of the Limits of Collaborative DCT-Based Image Denoising via Interpretable Neural Networks24 Sep 2026
- 2026One-Step Is Optimal: Unconditional Rectified Flows are Noise2Noise Denoisers, and Multi-Step Integration Provably Hurts---A Benchmark and Task-Based Detectability Study on Low-Dose CT15 Sep 2026
- 2026Noise2Noise Revisited: Training Pair Distributions Dominate Loss Choice in Self-Supervised Denoising15 Sep 2026
- 2026NOVA-GS: Noise-Aware View-Consistent Gaussian Splatting for Low-Light Novel View Synthesis11 Sep 2026
- 2026Physics-Driven Independent Pair Generation for Iterative Self-Supervised Low-Dose CT Denoising1 Sep 2026
- 2026Diffusion Based Unpaired Data Learning for Inverse Problems1 Sep 2026
12 newest of 338 All 338 (JSON)