Hurtful Words: Quantifying Biases in Clinical Contextual Word Embeddings
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Abstract (arXiv)
In this work, we examine the extent to which embeddings may encode marginalized populations differently, and how this may lead to a perpetuation of biases and worsened performance on clinical tasks. We pretrain deep embedding models (BERT) on medical notes from the MIMIC-III hospital dataset, and quantify potential disparities using two approaches. First, we identify dangerous latent relationships that are captured by the contextual word embeddings using a fill-in-the-blank method with text from real clinical notes and a log probability bias score quantification. Second, we evaluate performance gaps across different definitions of fairness on over 50 downstream clinical prediction tasks that include detection of acute and chronic conditions. We find that classifiers trained from BERT representations exhibit statistically significant differences in performance, often favoring the majority group with regards to gender, language, ethnicity, and insurance status. Finally, we explore shortcomings of using adversarial debiasing to obfuscate subgroup information in contextual word embeddings, and recommend best practices for such deep embedding models in clinical settings.
Key facts. Cited by 79 papers in the map (data through 7 Oct 2026). First posted on arXiv 11 Mar 2020.
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Citing papers per year: 2021: 12; 2022: 19; 2023: 20; 2024: 15; 2025: 9; 2026: 4.
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- 2022Large Language Models Encode Clinical Knowledge26 Dec 2022
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- 2024debiaSAE: Benchmarking and Mitigating Vision-Language Model Bias17 Oct 2024
- 2024Fairness and Bias in Multimodal AI: A Survey27 Jun 2024
- 2024The Minimum Information about CLinical Artificial Intelligence Checklist for Generative Modeling Research (MI-CLAIM-GEN)5 Mar 2024
- 2022Large Language Models Encode Clinical Knowledgecited by 1,807
- 2022LaMDA: Language Models for Dialog Applicationscited by 1,218
- 2023Toxicity in ChatGPT: Analyzing Persona-assigned Language Modelscited by 356
- 2022Training Data Influence Analysis and Estimation: A Surveycited by 134
- 2023Change is Hard: A Closer Look at Subpopulation Shiftcited by 119
- 2021Pre-trained Language Models in Biomedical Domain: A Systematic Surveycited by 87
- 2022Theories of "Gender" in NLP Bias Researchcited by 62
- 2023The Challenge of Using LLMs to Simulate Human Behavior: A Causal Inference Perspectivecited by 57
- 2022Improving the Fairness of Chest X-ray Classifierscited by 52
- 2023Event Stream GPT: A Data Pre-processing and Modeling Library for Generative, Pre-trained Transformers over Continuous-time Sequences of Complex Eventscited by 46
- 2022Towards Identifying Social Bias in Dialog Systems: Frame, Datasets, and Benchmarkscited by 36
- 2022BigBIO: A Framework for Data-Centric Biomedical Natural Language Processingcited by 36
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- 2026Vectors Are Not Neutral: Sensitive-Information Inference from Exported LLM Representations in Summarization26 May 2026
- 2026EQUITRIAGE: A Fairness Audit of Gender Bias in LLM-Based Emergency Department Triage5 May 2026
- 2025Can SAEs reveal and mitigate racial biases of LLMs in healthcare?31 Oct 2025
- 2025Exploring Gender Bias in Large Language Models: An In-depth Dive into the German Language22 Jul 2025
- 2025Application of CARE-SD text classifier tools to assess distribution of stigmatizing and doubt-marking language features in EHR11 Jul 2025
- 2025Probing AI Safety with Source Code25 Jun 2025
- 2025A Comprehensive Analysis of Large Language Model Outputs: Similarity, Diversity, and Bias14 May 2025
- 2025Unmasking Societal Biases in Respiratory Support for ICU Patients through Social Determinants of Health23 Feb 2025
- 2025A Comprehensive Survey on the Trustworthiness of Large Language Models in Healthcare21 Feb 2025
- 2025Elucidating Mechanisms of Demographic Bias in LLMs for Healthcare18 Feb 2025
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