MIMIC-Extract: A Data Extraction, Preprocessing, and Representation Pipeline for MIMIC-III
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Abstract (arXiv)
Robust machine learning relies on access to data that can be used with standardized frameworks in important tasks and the ability to develop models whose performance can be reasonably reproduced. In machine learning for healthcare, the community faces reproducibility challenges due to a lack of publicly accessible data and a lack of standardized data processing frameworks. We present MIMIC-Extract, an open-source pipeline for transforming raw electronic health record (EHR) data for critical care patients contained in the publicly-available MIMIC-III database into dataframes that are directly usable in common machine learning pipelines. MIMIC-Extract addresses three primary challenges in making complex health records data accessible to the broader machine learning community. First, it provides standardized data processing functions, including unit conversion, outlier detection, and aggregating semantically equivalent features, thus accounting for duplication and reducing missingness. Second, it preserves the time series nature of clinical data and can be easily integrated into clinically actionable prediction tasks in machine learning for health. Finally, it is highly extensible so that other researchers with related questions can easily use the same pipeline. We demonstrate the utility of this pipeline by showcasing several benchmark tasks and baseline results.
Key facts. Cited by 121 papers in the map (data through 7 Oct 2026). First posted on arXiv 19 Jul 2019.
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Citing papers per year: 2021: 11; 2022: 21; 2023: 23; 2024: 22; 2025: 29; 2026: 15.
121 papers.
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- 2021MultiBench: Multiscale Benchmarks for Multimodal Representation Learningcited by 143
- 2022Causal Transformer for Estimating Counterfactual Outcomescited by 121
- 2023EHRSHOT: An EHR Benchmark for Few-Shot Evaluation of Foundation Modelscited by 101
- 2023Benchmarking Distribution Shift in Tabular Data with TableShiftcited by 64
- 2023Warpformer: A Multi-scale Modeling Approach for Irregular Clinical Time Seriescited by 54
- 2021Generating Synthetic Mixed-type Longitudinal Electronic Health Records for Artificial Intelligent Applicationscited by 47
- 2023Event Stream GPT: A Data Pre-processing and Modeling Library for Generative, Pre-trained Transformers over Continuous-time Sequences of Complex Eventscited by 46
- 2022Diagnosing failures of fairness transfer across distribution shift in real-world medical settingscited by 45
- 2022An Extensive Data Processing Pipeline for MIMIC-IVcited by 39
- 2021Neural Natural Language Processing for Unstructured Data in Electronic Health Records: a Reviewcited by 35
- 2022GenHPF: General Healthcare Predictive Framework with Multi-task Multi-source Learningcited by 35
- 2024Time Series Diffusion in the Frequency Domaincited by 35
38 more
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- 2021Temporal Dependencies in Feature Importance for Time Series Predictionscited by 27
- 2021How to Leverage Multimodal EHR Data for Better Medical Predictions?cited by 26
- 2023Bayesian Neural Controlled Differential Equations for Treatment Effect Estimationcited by 26
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- 2023A Neural Framework for Generalized Causal Sensitivity Analysiscited by 17
- 2025EHR-R1: A Reasoning-Enhanced Foundational Language Model for Electronic Health Record Analysiscited by 17
- 2021Deconfounding Temporal Autoencoder: Estimating Treatment Effects over Time Using Noisy Proxiescited by 16
- 2021MIMIC-IF: Interpretability and Fairness Evaluation of Deep Learning Models on MIMIC-IV Datasetcited by 15
- 2023Coarse race data conceals disparities in clinical risk score performancecited by 15
- 2022Conditional Generation of Medical Time Series for Extrapolation to Underrepresented Populationscited by 14
- 2023Event-Based Contrastive Learning for Medical Time Seriescited by 13
- 2022Learning from a Biased Samplecited by 12
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- 2024Bayesian Neural Networks with Domain Knowledge Priorscited by 8
- 2024Stabilized Neural Prediction of Potential Outcomes in Continuous Timecited by 7
- 2021Real-time Mortality Prediction Using MIMIC-IV ICU Data Via Boosted Nonparametric Hazardscited by 6
- 2022Imputation Strategies Under Clinical Presence: Impact on Algorithmic Fairnesscited by 6
- 2024Constructing Confidence Intervals for Average Treatment Effects from Multiple Datasetscited by 6
- 2025Simple Yet Effective: An Information-Theoretic Approach to Multi-LLM Uncertainty Quantificationcited by 6
- 2022DeepJoint: Robust Survival Modelling Under Clinical Presence Shiftcited by 5
- 2024Benchmarking with MIMIC-IV, an irregular, spare clinical time series datasetcited by 5
- 2024Dynamic Survival Analysis for Early Event Predictioncited by 5
- 2025Revisiting the MIMIC-IV Benchmark: Experiments Using Language Models for Electronic Health Recordscited by 5
- 2021BEDS-Bench: Behavior of EHR-models under Distributional Shift--A Benchmarkcited by 4
- 2022Learning Optimal Dynamic Treatment Regimes Using Causal Tree Methods in Medicinecited by 4
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50 most cited of 121 All 121 (JSON)
- 2026Rethinking How We Evaluate Methodological Progress in Health AI16 Sep 2026
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- 2026A Systematic Evaluation of Imbalance Handling Methods in Biomedical Binary Classification13 May 2026
- 2026FeatEHR-LLM: Leveraging Large Language Models for Feature Engineering in Electronic Health Records24 Apr 2026
- 2026OC-Distill: Ontology-aware Contrastive Learning with Cross-Modal Distillation for ICU Risk Prediction18 Apr 2026
- 2026CAETC: Causal Autoencoding and Treatment Conditioning for Counterfactual Estimation over Time12 Mar 2026
38 more
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- 2025Synergizing Deconfounding and Temporal Generalization For Time-series Counterfactual Outcome Estimation20 Nov 2025
- 2025DeepBlip: Estimating Conditional Average Treatment Effects Over Time18 Nov 2025
- 2025SurvBench: A Standardised Preprocessing Pipeline for Multi-Modal Electronic Health Record Survival Analysis14 Nov 2025
- 2025EHR-R1: A Reasoning-Enhanced Foundational Language Model for Electronic Health Record Analysis29 Oct 2025
- 2025Closing Gaps: An Imputation Analysis of ICU Vital Signs28 Oct 2025
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- 2025ProtoEHR: Hierarchical Prototype Learning for EHR-based Healthcare Predictions23 Aug 2025
- 2025FairSSL: Fair Multimodal Self-Supervised Learning22 Aug 2025
- 2025Prediction of Survival Outcomes under Clinical Presence Shift: A Joint Neural Network Architecture7 Aug 2025
- 2025Simple Yet Effective: An Information-Theoretic Approach to Multi-LLM Uncertainty Quantification9 Jul 2025
- 2025LLM-Driven Treatment Effect Estimation Under Inference Time Text Confounding3 Jul 2025
- 2025Beyond Sensor Data: Foundation Models of Behavioral Data from Wearables Improve Health Predictions30 Jun 2025
- 2025Equitable Electronic Health Record Prediction with FAME: Fairness-Aware Multimodal Embedding16 Jun 2025
- 2025Leveraging MIMIC Datasets for Better Digital Health: A Review on Open Problems, Progress Highlights, and Future Promises15 Jun 2025
- 2025EHR2Path: Comprehensive Pathway-Level Modeling of Longitudinal Patient Trajectories from Multimodal Electronic Health Records5 Jun 2025
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- 2025A Diffusion-Based Method for Learning the Multi-Outcome Distribution of Medical Treatments2 Jun 2025
- 2025Scalable Unit Harmonization in Medical Informatics via Bayesian-Optimized Retrieval and Transformer-Based Re-ranking1 May 2025
- 2025Revisiting the MIMIC-IV Benchmark: Experiments Using Language Models for Electronic Health Records29 Apr 2025
- 2025DynaGraph: Interpretable Multi-Label Prediction from EHRs via Dynamic Graph Learning and Contrastive Augmentation28 Mar 2025
- 2025Unmasking Societal Biases in Respiratory Support for ICU Patients through Social Determinants of Health23 Feb 2025
- 2025Towards Unified Approaches in Self-Supervised Event Stream Modeling: Progress and Prospects7 Feb 2025
- 2025Contrastive Representation Learning Helps Cross-institutional Knowledge Transfer: A Study in Pediatric Ventilation Management23 Jan 2025
- 2025Challenges and recommendations for Electronic Health Records data extraction and preparation for dynamic prediction modelling in hospitalized patients -- a practical guide17 Jan 2025
- 2024Constructing Confidence Intervals for Average Treatment Effects from Multiple Datasets16 Dec 2024
- 2024Learning Predictive Checklists with Probabilistic Logic Programming25 Nov 2024
- 2024Towards Foundation Models for Critical Care Time Series25 Nov 2024
- 2024Ethical Challenges and Evolving Strategies in the Integration of Artificial Intelligence into Clinical Practice18 Nov 2024
- 2024ClinicalBench: Can LLMs Beat Traditional ML Models in Clinical Prediction?10 Nov 2024
- 2024CRTRE: Causal Rule Generation with Target Trial Emulation Framework10 Nov 2024
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- 2025MedAgentGym: A Scalable Agentic Training Environment for Code-Centric Reasoning in Biomedical Data Sciencecited by 22
- 2025EHR-R1: A Reasoning-Enhanced Foundational Language Model for Electronic Health Record Analysiscited by 17
- 2025Traj-CoA: Patient Trajectory Modeling via Chain-of-Agents for Lung Cancer Risk Predictioncited by 2
- 2025EHR-R1: A Reasoning-Enhanced Foundational Language Model for Electronic Health Record Analysis29 Oct 2025
- 2025Traj-CoA: Patient Trajectory Modeling via Chain-of-Agents for Lung Cancer Risk Prediction12 Oct 2025
- 2025MedAgentGym: A Scalable Agentic Training Environment for Code-Centric Reasoning in Biomedical Data Science4 Jun 2025
- 2024Time Series Diffusion in the Frequency Domaincited by 35
- 2024Time Series Diffusion in the Frequency Domain8 Feb 2024
- 2021MultiBench: Multiscale Benchmarks for Multimodal Representation Learningcited by 143
- 2022Causal Transformer for Estimating Counterfactual Outcomescited by 121
- 2023EHRSHOT: An EHR Benchmark for Few-Shot Evaluation of Foundation Modelscited by 101
- 2023Benchmarking Distribution Shift in Tabular Data with TableShiftcited by 64
- 2023Warpformer: A Multi-scale Modeling Approach for Irregular Clinical Time Seriescited by 54
- 2021Generating Synthetic Mixed-type Longitudinal Electronic Health Records for Artificial Intelligent Applicationscited by 47
- 2023Event Stream GPT: A Data Pre-processing and Modeling Library for Generative, Pre-trained Transformers over Continuous-time Sequences of Complex Eventscited by 46
- 2022Diagnosing failures of fairness transfer across distribution shift in real-world medical settingscited by 45
- 2022An Extensive Data Processing Pipeline for MIMIC-IVcited by 39
- 2021Neural Natural Language Processing for Unstructured Data in Electronic Health Records: a Reviewcited by 35
- 2022GenHPF: General Healthcare Predictive Framework with Multi-task Multi-source Learningcited by 35
- 2024ClinicalBench: Can LLMs Beat Traditional ML Models in Clinical Prediction?cited by 31
12 most cited of 116 All 116 (JSON)
- 2026Rethinking How We Evaluate Methodological Progress in Health AI16 Sep 2026
- 2026SUP-MIMIC: A Multi-Task Clinical Diagnosis Benchmark for Evaluating LLMs' Robustness to Contradictory Evidence30 Aug 2026
- 2026Tracing the Heart: An Evidence-Linked Pipeline for Heart-Failure Feature Engineering6 Aug 2026
- 2026MissHyper: Restoring Clinical Synchronicity in Missingness-Guided Hypergraph Forecasting24 Jul 2026
- 2026Causal Longitudinal Prior-Fitted Networks for Counterfactual Outcome Prediction4 Jun 2026
- 2026Croissant Baker: Metadata Generation for Discoverable, Governable, and Reusable ML Datasets14 May 2026
- 2026Smooth Multi-Policy Causal Effect Estimation in Longitudinal Settings14 May 2026
- 2026A Systematic Evaluation of Imbalance Handling Methods in Biomedical Binary Classification13 May 2026
- 2026FeatEHR-LLM: Leveraging Large Language Models for Feature Engineering in Electronic Health Records24 Apr 2026
- 2026OC-Distill: Ontology-aware Contrastive Learning with Cross-Modal Distillation for ICU Risk Prediction18 Apr 2026
- 2026CAETC: Causal Autoencoding and Treatment Conditioning for Counterfactual Estimation over Time12 Mar 2026
- 2026When Does Multimodal Learning Help in Healthcare? A Benchmark on EHR and Chest X-Ray Fusion27 Feb 2026
12 newest of 116 All 116 (JSON)