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MIMIC-Extract: A Data Extraction, Preprocessing, and Representation Pipeline for MIMIC-III

arXiv 1907.08322 ↗First posted 19 Jul 2019cs.LG stat.MLcited by 121

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Abstract (arXiv)

Robust machine learning relies on access to data that can be used with standardized frameworks in important tasks and the ability to develop models whose performance can be reasonably reproduced. In machine learning for healthcare, the community faces reproducibility challenges due to a lack of publicly accessible data and a lack of standardized data processing frameworks. We present MIMIC-Extract, an open-source pipeline for transforming raw electronic health record (EHR) data for critical care patients contained in the publicly-available MIMIC-III database into dataframes that are directly usable in common machine learning pipelines. MIMIC-Extract addresses three primary challenges in making complex health records data accessible to the broader machine learning community. First, it provides standardized data processing functions, including unit conversion, outlier detection, and aggregating semantically equivalent features, thus accounting for duplication and reducing missingness. Second, it preserves the time series nature of clinical data and can be easily integrated into clinically actionable prediction tasks in machine learning for health. Finally, it is highly extensible so that other researchers with related questions can easily use the same pipeline. We demonstrate the utility of this pipeline by showcasing several benchmark tasks and baseline results.

Key facts. Cited by 121 papers in the map (data through 7 Oct 2026). First posted on arXiv 19 Jul 2019.

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2021: 11; 2022: 21; 2023: 23; 2024: 22; 2025: 29; 2026: 15.

121 papers.

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  1. 2021MultiBench: Multiscale Benchmarks for Multimodal Representation Learningcited by 143
  2. 2022Causal Transformer for Estimating Counterfactual Outcomescited by 121
  3. 2023EHRSHOT: An EHR Benchmark for Few-Shot Evaluation of Foundation Modelscited by 101
  4. 2023Benchmarking Distribution Shift in Tabular Data with TableShiftcited by 64
  5. 2023Warpformer: A Multi-scale Modeling Approach for Irregular Clinical Time Seriescited by 54
  6. 2021Generating Synthetic Mixed-type Longitudinal Electronic Health Records for Artificial Intelligent Applicationscited by 47
  7. 2023Event Stream GPT: A Data Pre-processing and Modeling Library for Generative, Pre-trained Transformers over Continuous-time Sequences of Complex Eventscited by 46
  8. 2022Diagnosing failures of fairness transfer across distribution shift in real-world medical settingscited by 45
  9. 2022An Extensive Data Processing Pipeline for MIMIC-IVcited by 39
  10. 2021Neural Natural Language Processing for Unstructured Data in Electronic Health Records: a Reviewcited by 35
  11. 2022GenHPF: General Healthcare Predictive Framework with Multi-task Multi-source Learningcited by 35
  12. 2024Time Series Diffusion in the Frequency Domaincited by 35
38 more
  1. 2024ClinicalBench: Can LLMs Beat Traditional ML Models in Clinical Prediction?cited by 31
  2. 2021Benchmarking emergency department triage prediction models with machine learning and large public electronic health recordscited by 30
  3. 2022Estimating average causal effects from patient trajectoriescited by 29
  4. 2021Temporal Dependencies in Feature Importance for Time Series Predictionscited by 27
  5. 2021How to Leverage Multimodal EHR Data for Better Medical Predictions?cited by 26
  6. 2023Bayesian Neural Controlled Differential Equations for Treatment Effect Estimationcited by 26
  7. 2023Multimodal Clinical Benchmark for Emergency Care (MC-BEC): A Comprehensive Benchmark for Evaluating Foundation Models in Emergency Medicinecited by 24
  8. 2025MedAgentGym: A Scalable Agentic Training Environment for Code-Centric Reasoning in Biomedical Data Sciencecited by 22
  9. 2022Classification of datasets with imputed missing values: does imputation quality matter?cited by 21
  10. 2022Clinical Prompt Learning with Frozen Language Modelscited by 19
  11. 2022The Missing Indicator Method: From Low to High Dimensionscited by 19
  12. 2025Beyond Sensor Data: Foundation Models of Behavioral Data from Wearables Improve Health Predictionscited by 18
  13. 2023A Neural Framework for Generalized Causal Sensitivity Analysiscited by 17
  14. 2025EHR-R1: A Reasoning-Enhanced Foundational Language Model for Electronic Health Record Analysiscited by 17
  15. 2021Deconfounding Temporal Autoencoder: Estimating Treatment Effects over Time Using Noisy Proxiescited by 16
  16. 2021MIMIC-IF: Interpretability and Fairness Evaluation of Deep Learning Models on MIMIC-IV Datasetcited by 15
  17. 2023Coarse race data conceals disparities in clinical risk score performancecited by 15
  18. 2022Conditional Generation of Medical Time Series for Extrapolation to Underrepresented Populationscited by 14
  19. 2023Event-Based Contrastive Learning for Medical Time Seriescited by 13
  20. 2022Learning from a Biased Samplecited by 12
  21. 2023General-Purpose Retrieval-Enhanced Medical Prediction Model Using Near-Infinite Historycited by 12
  22. 2024When Raw Data Prevails: Are Large Language Model Embeddings Effective in Numerical Data Representation for Medical Machine Learning Applications?cited by 11
  23. 2024IGC-Net for conditional average potential outcome estimation over timecited by 10
  24. 2022Unsupervised pre-training of graph transformers on patient population graphscited by 9
  25. 2024ED-Copilot: Reduce Emergency Department Wait Time with Language Model Diagnostic Assistancecited by 9
  26. 2024Bayesian Neural Networks with Domain Knowledge Priorscited by 8
  27. 2024Stabilized Neural Prediction of Potential Outcomes in Continuous Timecited by 7
  28. 2021Real-time Mortality Prediction Using MIMIC-IV ICU Data Via Boosted Nonparametric Hazardscited by 6
  29. 2022Imputation Strategies Under Clinical Presence: Impact on Algorithmic Fairnesscited by 6
  30. 2024Constructing Confidence Intervals for Average Treatment Effects from Multiple Datasetscited by 6
  31. 2025Simple Yet Effective: An Information-Theoretic Approach to Multi-LLM Uncertainty Quantificationcited by 6
  32. 2022DeepJoint: Robust Survival Modelling Under Clinical Presence Shiftcited by 5
  33. 2024Benchmarking with MIMIC-IV, an irregular, spare clinical time series datasetcited by 5
  34. 2024Dynamic Survival Analysis for Early Event Predictioncited by 5
  35. 2025Revisiting the MIMIC-IV Benchmark: Experiments Using Language Models for Electronic Health Recordscited by 5
  36. 2021BEDS-Bench: Behavior of EHR-models under Distributional Shift--A Benchmarkcited by 4
  37. 2022Learning Optimal Dynamic Treatment Regimes Using Causal Tree Methods in Medicinecited by 4
  38. 2022UniHPF : Universal Healthcare Predictive Framework with Zero Domain Knowledgecited by 4

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