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CE-Net: Context Encoder Network for 2D Medical Image Segmentation

arXiv 1903.02740 ↗First posted 7 Mar 2019cs.CVcited by 219

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Abstract (arXiv)

Medical image segmentation is an important step in medical image analysis. With the rapid development of convolutional neural network in image processing, deep learning has been used for medical image segmentation, such as optic disc segmentation, blood vessel detection, lung segmentation, cell segmentation, etc. Previously, U-net based approaches have been proposed. However, the consecutive pooling and strided convolutional operations lead to the loss of some spatial information. In this paper, we propose a context encoder network (referred to as CE-Net) to capture more high-level information and preserve spatial information for 2D medical image segmentation. CE-Net mainly contains three major components: a feature encoder module, a context extractor and a feature decoder module. We use pretrained ResNet block as the fixed feature extractor. The context extractor module is formed by a newly proposed dense atrous convolution (DAC) block and residual multi-kernel pooling (RMP) block. We applied the proposed CE-Net to different 2D medical image segmentation tasks. Comprehensive results show that the proposed method outperforms the original U-Net method and other state-of-the-art methods for optic disc segmentation, vessel detection, lung segmentation, cell contour segmentation and retinal optical coherence tomography layer segmentation.

Key facts. Cited by 219 papers in the map (data through 7 Oct 2026). First posted on arXiv 7 Mar 2019.

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2021: 35; 2022: 53; 2023: 41; 2024: 41; 2025: 30; 2026: 19.

219 papers.

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  1. 2021Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentationcited by 1,218
  2. 2021UNETR: Transformers for 3D Medical Image Segmentationcited by 954
  3. 2022Transformers in Medical Imaging: A Surveycited by 245
  4. 2022MedSegDiff: Medical Image Segmentation with Diffusion Probabilistic Modelcited by 180
  5. 2024U-KAN Makes Strong Backbone for Medical Image Segmentation and Generationcited by 176
  6. 2021MISSFormer: An Effective Medical Image Segmentation Transformercited by 103
  7. 2023Ambiguous Medical Image Segmentation using Diffusion Modelscited by 92
  8. 2023SegVol: Universal and Interactive Volumetric Medical Image Segmentationcited by 86
  9. 2023Semantic Segmentation using Vision Transformers: A surveycited by 73
  10. 2021Inconsistency-aware Uncertainty Estimation for Semi-supervised Medical Image Segmentationcited by 61
  11. 2024LightM-UNet: Mamba Assists in Lightweight UNet for Medical Image Segmentationcited by 54
  12. 2021Multi-Compound Transformer for Accurate Biomedical Image Segmentationcited by 42
38 more
  1. 2021TransClaw U-Net: Claw U-Net with Transformers for Medical Image Segmentationcited by 41
  2. 2023Beyond Adapting SAM: Towards End-to-End Ultrasound Image Segmentation via Auto Promptingcited by 40
  3. 2021Boundary-aware Transformers for Skin Lesion Segmentationcited by 39
  4. 2022REFUGE2 Challenge: A Treasure Trove for Multi-Dimension Analysis and Evaluation in Glaucoma Screeningcited by 37
  5. 2022D-Former: A U-shaped Dilated Transformer for 3D Medical Image Segmentationcited by 35
  6. 2023Directional Connectivity-based Segmentation of Medical Imagescited by 30
  7. 2021Coarse to Fine Multi-Resolution Temporal Convolutional Networkcited by 28
  8. 2024Modality-agnostic Domain Generalizable Medical Image Segmentation by Multi-Frequency in Multi-Scale Attentioncited by 26
  9. 2023MIS-FM: 3D Medical Image Segmentation using Foundation Models Pretrained on a Large-Scale Unannotated Datasetcited by 25
  10. 2022C2F-TCN: A Framework for Semi and Fully Supervised Temporal Action Segmentationcited by 23
  11. 2021Modality specific U-Net variants for biomedical image segmentation: A surveycited by 20
  12. 2023Frequency-mixed Single-source Domain Generalization for Medical Image Segmentationcited by 20
  13. 2023Retinal Vessel Segmentation via a Multi-resolution Contextual Network and Adversarial Learningcited by 19
  14. 2022AADG: Automatic Augmentation for Domain Generalization on Retinal Image Segmentationcited by 18
  15. 2022Fuzzy Attention Neural Network to Tackle Discontinuity in Airway Segmentationcited by 18
  16. 2024T-Mamba: A unified framework with Long-Range Dependency in dual-domain for 2D & 3D Tooth Segmentationcited by 17
  17. 2021Improving Camouflaged Object Detection with the Uncertainty of Pseudo-edge Labelscited by 16
  18. 2022Omni-Seg: A Scale-aware Dynamic Network for Renal Pathological Image Segmentationcited by 16
  19. 2022BCS-Net: Boundary, Context and Semantic for Automatic COVID-19 Lung Infection Segmentation from CT Imagescited by 16
  20. 2024A Comprehensive Survey of Convolutions in Deep Learning: Applications, Challenges, and Future Trendscited by 16
  21. 2021LensID: A CNN-RNN-Based Framework Towards Lens Irregularity Detection in Cataract Surgery Videoscited by 15
  22. 2022CAT-Net: A Cross-Slice Attention Transformer Model for Prostate Zonal Segmentation in MRIcited by 15
  23. 2022RTNet: Relation Transformer Network for Diabetic Retinopathy Multi-lesion Segmentationcited by 14
  24. 2022BATFormer: Towards Boundary-Aware Lightweight Transformer for Efficient Medical Image Segmentationcited by 14
  25. 2023FedA3I: Annotation Quality-Aware Aggregation for Federated Medical Image Segmentation against Heterogeneous Annotation Noisecited by 14
  26. 2022Factorizer: A Scalable Interpretable Approach to Context Modeling for Medical Image Segmentationcited by 12
  27. 2022RAVIR: A Dataset and Methodology for the Semantic Segmentation and Quantitative Analysis of Retinal Arteries and Veins in Infrared Reflectance Imagingcited by 12
  28. 2022Physiology-based simulation of the retinal vasculature enables annotation-free segmentation of OCT angiographscited by 12
  29. 2022Boundary Guided Semantic Learning for Real-time COVID-19 Lung Infection Segmentation Systemcited by 11
  30. 2023DVPT: Dynamic Visual Prompt Tuning of Large Pre-trained Models for Medical Image Analysiscited by 11
  31. 2024Clustering Propagation for Universal Medical Image Segmentationcited by 11
  32. 2024CC-SAM: SAM with Cross-feature Attention and Context for Ultrasound Image Segmentationcited by 11
  33. 2022MFSNet: A Multi Focus Segmentation Network for Skin Lesion Segmentationcited by 10
  34. 2023Feature Enhancer Segmentation Network (FES-Net) for Vessel Segmentationcited by 10
  35. 2025A Comprehensive Review of U-Net and Its Variants: Advances and Applications in Medical Image Segmentationcited by 10
  36. 2021Automatic Segmentation of Organs-at-Risk from Head-and-Neck CT using Separable Convolutional Neural Network with Hard-Region-Weighted Losscited by 9
  37. 2022The Lighter The Better: Rethinking Transformers in Medical Image Segmentation Through Adaptive Pruningcited by 9
  38. 2023Rethinking Boundary Detection in Deep Learning Models for Medical Image Segmentationcited by 9

50 most cited of 219 All 219 (JSON)