MISSFormer: An Effective Medical Image Segmentation Transformer
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Abstract (arXiv)
The CNN-based methods have achieved impressive results in medical image segmentation, but they failed to capture the long-range dependencies due to the inherent locality of the convolution operation. Transformer-based methods are recently popular in vision tasks because of their capacity for long-range dependencies and promising performance. However, it lacks in modeling local context. In this paper, taking medical image segmentation as an example, we present MISSFormer, an effective and powerful Medical Image Segmentation tranSFormer. MISSFormer is a hierarchical encoder-decoder network with two appealing designs: 1) A feed-forward network is redesigned with the proposed Enhanced Transformer Block, which enhances the long-range dependencies and supplements the local context, making the feature more discriminative. 2) We proposed Enhanced Transformer Context Bridge, different from previous methods of modeling only global information, the proposed context bridge with the enhanced transformer block extracts the long-range dependencies and local context of multi-scale features generated by our hierarchical transformer encoder. Driven by these two designs, the MISSFormer shows a solid capacity to capture more discriminative dependencies and context in medical image segmentation. The experiments on multi-organ and cardiac segmentation tasks demonstrate the superiority, effectiveness and robustness of our MISSFormer, the experimental results of MISSFormer trained from scratch even outperform state-of-the-art methods pre-trained on ImageNet. The core designs can be generalized to other visual segmentation tasks. The code has been released on Github: https://github.com/ZhifangDeng/MISSFormer
Key facts. Cited by 103 papers in the map (data through 7 Oct 2026). Builds on 36 of its 39 references that are in the map. First posted on arXiv 15 Sep 2021.
Builds on
36 of 39 references.
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Citing papers per year: 2022: 25; 2023: 26; 2024: 22; 2025: 17; 2026: 13.
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- 2026MS-DKC: A Dataset Knowledge Card Framework for Designing and Adapting Medical Image Segmentation Models4 Jun 2026
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- 2026EEO-TFV: Escape-Explore Optimizer for Web-Scale Time-Series Forecasting and Vision Analysis30 Jan 2026
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