Directional Connectivity-based Segmentation of Medical Images
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Abstract (arXiv)
Anatomical consistency in biomarker segmentation is crucial for many medical image analysis tasks. A promising paradigm for achieving anatomically consistent segmentation via deep networks is incorporating pixel connectivity, a basic concept in digital topology, to model inter-pixel relationships. However, previous works on connectivity modeling have ignored the rich channel-wise directional information in the latent space. In this work, we demonstrate that effective disentanglement of directional sub-space from the shared latent space can significantly enhance the feature representation in the connectivity-based network. To this end, we propose a directional connectivity modeling scheme for segmentation that decouples, tracks, and utilizes the directional information across the network. Experiments on various public medical image segmentation benchmarks show the effectiveness of our model as compared to the state-of-the-art methods. Code is available at https://github.com/Zyun-Y/DconnNet.
Key facts. Cited by 30 papers in the map (data through 14 Oct 2026). Builds on 41 of its 92 references that are in the map. First posted on arXiv 31 Mar 2023.
Builds on
41 of 92 references.
References · 41
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- 2020clDice -- A Novel Topology-Preserving Loss Function for Tubular Structure Segmentationcited by 294
- 2018Context Encoding for Semantic Segmentationcited by 290
- 2013Predicting Parameters in Deep Learningcited by 224
- 2019CE-Net: Context Encoder Network for 2D Medical Image Segmentationcited by 220
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Citing papers per year: 2024: 11; 2025: 12; 2026: 7.
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- 2024A Survey of Camouflaged Object Detection and Beyondcited by 37
- 2024Representing Topological Self-Similarity Using Fractal Feature Maps for Accurate Segmentation of Tubular Structurescited by 13
- 2024MSVM-UNet: Multi-Scale Vision Mamba UNet for Medical Image Segmentationcited by 7
- 2024LSSF-Net: Lightweight Segmentation with Self-Awareness, Spatial Attention, and Focal Modulationcited by 4
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- 2024Spectral U-Net: Enhancing Medical Image Segmentation via Spectral Decompositioncited by 2
- 2025GraphMorph: Tubular Structure Extraction by Morphing Predicted Graphscited by 2
- 2025Unified Medical Image Segmentation with State Space Modeling Snakecited by 2
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- 2025Not All Pixels Are Equal: Pixel-wise Meta-Learning for Medical Segmentation with Noisy Labelscited by 0
- 2026TFFM: Topology-Aware Feature Fusion Module via Latent Graph Reasoning for Retinal Vessel Segmentationcited by 0
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- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigmscited by 0
- 2026BSC-Net: A Small-Branch-Sensitive Structural Continuity Network for Coronary Vessel Segmentation and Quantitative Angiographic Analysiscited by 0
- 2026BSC-Net: A Small-Branch-Sensitive Structural Continuity Network for Coronary Vessel Segmentation and Quantitative Angiographic Analysis14 Sep 2026
- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigms29 Jun 2026
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- 2026Continuous-tone Simple Points: An ℓ0-Norm of Cyclic Gradient for Topology-Preserving Data-Driven Image Segmentation30 Apr 2026
- 2026FMS2: Unified Flow Matching for Segmentation and Synthesis of Thin Structures14 Mar 2026
- 2026TFFM: Topology-Aware Feature Fusion Module via Latent Graph Reasoning for Retinal Vessel Segmentation27 Jan 2026
- 2026Topology-Guaranteed Image Segmentation: Enforcing Connectivity, Genus, and Width Constraints16 Jan 2026
- 2025Not All Pixels Are Equal: Pixel-wise Meta-Learning for Medical Segmentation with Noisy Labels24 Nov 2025
- 2025AngioDG: Interpretable Channel-informed Feature-modulated Single-source Domain Generalization for Coronary Vessel Segmentation in X-ray Angiography21 Nov 2025
- 2025Dual-supervised Asymmetric Co-training for Semi-supervised Medical Domain Generalization25 Sep 2025
- 2025Deep Self-knowledge Distillation: A hierarchical supervised learning for coronary artery segmentation3 Sep 2025
- 2025DCFFSNet: Deep Connectivity Feature Fusion Separation Network for Medical Image Segmentation24 Jul 2025
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- 2025Similarity Memory Prior is All You Need for Medical Image Segmentation1 Jul 2025
- 2025C3S3: Complementary Competition and Contrastive Selection for Semi-Supervised Medical Image Segmentation9 Jun 2025
- 2025Decoupled Competitive Framework for Semi-supervised Medical Image Segmentation30 May 2025
- 2025Pairwise Similarity Regularization for Semi-supervised Graph Medical Image Segmentation17 Mar 2025
- 2025GraphMorph: Tubular Structure Extraction by Morphing Predicted Graphs17 Feb 2025
- 2024Optimized Vessel Segmentation: A Structure-Agnostic Approach with Small Vessel Enhancement and Morphological Correction22 Nov 2024
- 2024Spectral U-Net: Enhancing Medical Image Segmentation via Spectral Decomposition13 Sep 2024
- 2024D2-MLP: Dynamic Decomposed MLP Mixer for Medical Image Segmentation13 Sep 2024
- 2024LSSF-Net: Lightweight Segmentation with Self-Awareness, Spatial Attention, and Focal Modulation3 Sep 2024
- 2024A Survey of Camouflaged Object Detection and Beyond26 Aug 2024
- 2024MSVM-UNet: Multi-Scale Vision Mamba UNet for Medical Image Segmentation25 Aug 2024
- 2024Anatomical Consistency Distillation and Inconsistency Synthesis for Brain Tumor Segmentation with Missing Modalities25 Aug 2024
- 2024Mamba meets crack segmentation22 Jul 2024
- 2024Representing Topological Self-Similarity Using Fractal Feature Maps for Accurate Segmentation of Tubular Structures20 Jul 2024
- 2024Inter- and intra-uncertainty based feature aggregation model for semi-supervised histopathology image segmentation19 Mar 2024
- 2024Spatial Coherence Loss: All Objects Matter in Salient and Camouflaged Object Detection28 Feb 2024
- 2024MSVM-UNet: Multi-Scale Vision Mamba UNet for Medical Image Segmentationcited by 7
- 2025Unified Medical Image Segmentation with State Space Modeling Snakecited by 2
- 2024Mamba meets crack segmentationcited by 1
- 2025Unified Medical Image Segmentation with State Space Modeling Snake17 Jul 2025
- 2024MSVM-UNet: Multi-Scale Vision Mamba UNet for Medical Image Segmentation25 Aug 2024
- 2024Mamba meets crack segmentation22 Jul 2024
- 2024A Survey of Camouflaged Object Detection and Beyondcited by 37
- 2024Representing Topological Self-Similarity Using Fractal Feature Maps for Accurate Segmentation of Tubular Structurescited by 13
- 2024LSSF-Net: Lightweight Segmentation with Self-Awareness, Spatial Attention, and Focal Modulationcited by 4
- 2024Inter- and intra-uncertainty based feature aggregation model for semi-supervised histopathology image segmentationcited by 3
- 2024Anatomical Consistency Distillation and Inconsistency Synthesis for Brain Tumor Segmentation with Missing Modalitiescited by 2
- 2024Spectral U-Net: Enhancing Medical Image Segmentation via Spectral Decompositioncited by 2
- 2025GraphMorph: Tubular Structure Extraction by Morphing Predicted Graphscited by 2
- 2026Topology-Guaranteed Image Segmentation: Enforcing Connectivity, Genus, and Width Constraintscited by 2
- 2024Spatial Coherence Loss: All Objects Matter in Salient and Camouflaged Object Detectioncited by 1
- 2025Similarity Memory Prior is All You Need for Medical Image Segmentationcited by 1
- 2025Dual-supervised Asymmetric Co-training for Semi-supervised Medical Domain Generalizationcited by 1
- 2025AngioDG: Interpretable Channel-informed Feature-modulated Single-source Domain Generalization for Coronary Vessel Segmentation in X-ray Angiographycited by 1
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- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigms29 Jun 2026
- 2026RoadGIE: Towards A Global-Scale Aerial Benchmark for Generalizable Interactive Road Extraction26 May 2026
- 2026Continuous-tone Simple Points: An ℓ0-Norm of Cyclic Gradient for Topology-Preserving Data-Driven Image Segmentation30 Apr 2026
- 2026TFFM: Topology-Aware Feature Fusion Module via Latent Graph Reasoning for Retinal Vessel Segmentation27 Jan 2026
- 2026Topology-Guaranteed Image Segmentation: Enforcing Connectivity, Genus, and Width Constraints16 Jan 2026
- 2025Not All Pixels Are Equal: Pixel-wise Meta-Learning for Medical Segmentation with Noisy Labels24 Nov 2025
- 2025AngioDG: Interpretable Channel-informed Feature-modulated Single-source Domain Generalization for Coronary Vessel Segmentation in X-ray Angiography21 Nov 2025
- 2025Dual-supervised Asymmetric Co-training for Semi-supervised Medical Domain Generalization25 Sep 2025
- 2025DCFFSNet: Deep Connectivity Feature Fusion Separation Network for Medical Image Segmentation24 Jul 2025
- 2025Deformable Convolution Module with Globally Learned Relative Offsets for Fundus Vessel Segmentation24 Jul 2025
- 2025Similarity Memory Prior is All You Need for Medical Image Segmentation1 Jul 2025
12 newest of 25 All 25 (JSON)