mlsanityData to 14 Oct 2026

Generated Context versus Governed State: Functional Conditions for Accountable Longitudinal Clinical Reasoning

arXiv 2608.14804 ↗First posted 14 Aug 2026cs.AIcited by 0

On the map: LLM reasoning → Clinical and biomedical applications

Abstract (arXiv)

Large language models (LLMs) have become the dominant interface of clinical artificial intelligence, yet the interface they expose (text in, text out, one context window at a time) maintains no explicit, persistent, governed representation of what is currently true about a patient. This paper argues that longitudinal clinical reasoning is a state-estimation problem under partial observability, and that the axis on which clinical AI succeeds or fails is not the fluency of the model reading the record but the governance of the patient state it reasons over. We distinguish generated context from governed state; separate five objects that clinical AI habitually conflates (true state, observations, evidence, belief, and simulated state); define a tiered governance standard against which any clinical AI system can be audited; and show that an operational definition of accountability decomposes into four information requirements: an immutable evidence ledger with awareness-time versioning, a belief state distinct from accumulated evidence, an observation-process model, and claim-level causal typing. We are explicit that this decomposition is analytic rather than a necessity theorem, and that its value is conceptual hygiene: it converts "accountable clinical AI" from a slogan into an audit instrument. A six-level maturity framework separates what a system makes governable from what it can compute, locating current LLM-centric practice at high capability but low maturity. The paper is fully self-contained: the four research questions the framework poses are stated in the introduction, and the conclusion records what the paper establishes toward each; future work develops the buildable core of the architecture and the research program toward full Clinical World Models. No empirical result is claimed here.

Key facts. No citing papers in the map yet (data through 14 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 12 of its 28 references that are in the map. First posted on arXiv 14 Aug 2026.

Builds on

12 of 28 references.

References · 12

  1. 2023Mastering Diverse Domains through World Modelscited by 1,253
  2. 2023Capabilities of GPT-4 on Medical Challenge Problemscited by 638
  3. 2017Neural-Symbolic Learning and Reasoning: A Survey and Interpretationcited by 196
  4. 2026EHRWorld: A Patient-Centric Medical World Model for Long-Horizon Clinical Trajectoriescited by 19
  5. 2025Beyond Generative AI: World Models for Clinical Prediction, Counterfactuals, and Planningcited by 9
  6. 2026Medical world models in healthcare: foundations, applications, and challenges for trustworthy clinical translationcited by 4
  7. 2026The Patient is not a Moving Document: A World Model Training Paradigm for Longitudinal EHRcited by 3
  8. 2026Agents-K1: Towards Agent-native Knowledge Orchestrationcited by 3
  9. 2026Towards World Models in Biomedical Researchcited by 2
  10. 2026MedBeads: An AI-Native Clinical Context Graph Built from Immutable Beads and Reconstructable Clinical Linkscited by 1
  11. 2026Grounding Clinical AI Competency in Human Cognition Through the Clinical World Model and Skill-Mix Frameworkcited by 1
  12. 2026CalTwin: Towards Calibrated, Shift-Robust Medical World Models via Fisher-Information Regularisationcited by 1

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  1. 2026Beyond Medical Chatbots: Meddollina and the Rise of Continuous Clinical Intelligence
  2. 2026Beyond Prediction: Longitudinal Reasoning in EHR-Integrated Clinical AI ↗
  3. 2025Compartmentalised Agentic Reasoning for Clinical NLI
  4. 2026A rubric landscape for evaluating clinical reasoning in large language models: what exists, what is missing, and what needs to be combined
  5. 2026The Verbose Context Problem in Medical Records
  6. 2024Critique of Impure Reason: Unveiling the reasoning behaviour of medical Large Language Models
  7. 2026Can LLMs Reason Over Long Horizons? An Empirical Evaluation of Context Strategies for Longitudinal Clinical Reasoning
  8. 2026Aligning Clinical Needs and AI Capabilities: A Survey on LLMs for Medical Reasoning