mlsanityData to 14 Oct 2026

Reinforcement Learning in the Real World: A Survey of Statistical Challenges and Future Directions

arXiv 2601.15353 ↗First posted 21 Jan 2026stat.AP cs.LG stat.MLcited by 5

On the map: Deep reinforcement learning methods → RL for clinical treatment and surgery

Abstract (arXiv)

Reinforcement learning (RL) has achieved remarkable success in real-world decision-making across diverse domains, including gaming, robotics, online advertising, public health, and natural language processing. Despite these advances, a substantial gap remains between RL research and its deployment in many practical settings. Two recurring challenges often underlie this gap. First, many settings offer limited opportunity for the agent to interact extensively with the target environment due to practical constraints. Second, many target environments often undergo substantial changes, requiring redesign and redeployment of RL systems (e.g., advancements in science and technology that change the landscape of healthcare delivery). Addressing these challenges and bridging the gap between basic research and application requires theory and methodology that directly inform the design, implementation, and continual improvement of RL systems in real-world settings. In this paper, we frame the application of RL in practice as a three-component process: (i) online learning and optimization during deployment, (ii) post- or between-deployment offline analyses, and (iii) repeated cycles of deployment and redeployment to continually improve the RL system. We provide a narrative review of recent advances that address the statistical challenges arising across these three components, including methods for enhancing sample efficiency during online deployment, maximizing data utility for post- or between-deployment inference, and designing sequences of deployments for continual improvement. We also outline future research directions in RL that are use-inspired -- aiming for impactful application of RL in practice.

Key facts. Cited by 5 papers in the map (data through 14 Oct 2026). Placed in RL for clinical treatment and surgery, one of 15 directions in Deep reinforcement learning methods. Builds on 136 of its 220 references that are in the map. First posted on arXiv 21 Jan 2026.

Builds on

136 of 220 references.

Closest ancestors · 2

Same direction, newest first

  1. 2025Language Agents for Hypothesis-driven Clinical Decision Making with Reinforcement Learning16 Jun
  2. 2025Reinforcement Learning on Dyads to Enhance Medication Adherence6 Feb

Other references · 134

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38 more
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Cited by year (2026 to 14 Oct)

Citing papers per year: 2026: 5.

5 papers.

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Close in wording, no citation either way

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  3. 2023Understanding Reinforcement Learning Algorithms: The Progress from Basic Q-learning to Proximal Policy Optimization
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  6. 2024Safe and Robust Reinforcement Learning: Principles and Practice
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