mlsanityData to 14 Oct 2026

Poison Once, Refuse Forever: Weaponizing Alignment for Injecting Bias in LLMs

arXiv 2508.20333 ↗First posted 28 Aug 2025cs.LG cs.AI cs.CLcited by 1

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Abstract (arXiv)

Large Language Models (LLMs) are aligned to meet ethical standards and safety requirements by training them to refuse answering harmful or unsafe prompts. In this paper, we demonstrate how adversaries can exploit LLMs' alignment to implant bias, or enforce targeted censorship without degrading the model's responsiveness to unrelated topics. Specifically, we propose Subversive Alignment Injection (SAI), a poisoning attack that leverages the alignment mechanism to trigger refusal on specific topics or queries predefined by the adversary. Although it is perhaps not surprising that refusal can be induced through overalignment, we demonstrate how this refusal can be exploited to inject bias into the model. Surprisingly, SAI evades state-of-the-art poisoning defenses including LLM state forensics, as well as robust aggregation techniques that are designed to detect poisoning in FL settings. We demonstrate the practical dangers of this attack by illustrating its end-to-end impacts on LLM-powered application pipelines. For chat based applications such as ChatDoctor, with 1% data poisoning, the system refuses to answer healthcare questions to targeted racial category leading to high bias (Delta DP of 23%). We also show that bias can be induced in other NLP tasks: for a resume selection pipeline aligned to refuse to summarize CVs from a selected university, high bias in selection (Delta DP of 27%) results. Even higher bias (Delta DP~38%) results on 9 other chat based downstream applications.

Key facts. Cited by 1 paper in the map (data through 14 Oct 2026). Builds on 58 of its 82 references that are in the map. First posted on arXiv 28 Aug 2025.

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58 of 82 references.

References · 58

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38 more
  1. 2024Parameter-Efficient Fine-Tuning for Large Models: A Comprehensive Surveycited by 656
  2. 2023An Empirical Study of Catastrophic Forgetting in Large Language Models During Continual Fine-tuningcited by 639
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  9. 2023Poisoning Web-Scale Training Datasets is Practicalcited by 290
  10. 2023Poisoning Language Models During Instruction Tuningcited by 269
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  12. 2024Foundational Challenges in Assuring Alignment and Safety of Large Language Modelscited by 199
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  14. 2018Mitigating Sybils in Federated Learning Poisoningcited by 161
  15. 2023Backdooring Instruction-Tuned Large Language Models with Virtual Prompt Injectioncited by 157
  16. 2023Should ChatGPT be Biased? Challenges and Risks of Bias in Large Language Modelscited by 148
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  30. 2022CrowdGuard: Federated Backdoor Detection in Federated Learningcited by 27
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  1. 2025From Threat to Tool: Leveraging Refusal-Aware Injection Attacks for Safety Alignment
  2. 2024Enhancing Prompt Injection Attacks to LLMs via Poisoning Alignment
  3. 2025An Embarrassingly Simple Defense Against LLM Abliteration Attacks
  4. 2026Deactivating Refusal Triggers: Understanding and Mitigating Overrefusal in Safety Alignment
  5. 2026LLMs Can Unlearn Refusal with Only 1,000 Benign Samples
  6. 2025Revisiting Backdoor Attacks on LLMs: A Stealthy and Practical Poisoning Framework via Harmless Inputs
  7. 2026When Safety Becomes a Vulnerability: Exploiting LLM Alignment Homogeneity for Transferable Blocking in RAG
  8. 2025Jailbreaking LLMs via Semantically Relevant Nested Scenarios with Targeted Toxic Knowledge