mlsanityData to 7 Oct 2026

LLM-MedQA: Enhancing Medical Question Answering through Case Studies in Large Language Models

arXiv 2501.05464 ↗First posted 31 Dec 2024cs.CL cs.AI cs.IRcited by 31

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Abstract (arXiv)

Accurate and efficient question-answering systems are essential for delivering high-quality patient care in the medical field. While Large Language Models (LLMs) have made remarkable strides across various domains, they continue to face significant challenges in medical question answering, particularly in understanding domain-specific terminologies and performing complex reasoning. These limitations undermine their effectiveness in critical medical applications. To address these issues, we propose a novel approach incorporating similar case generation within a multi-agent medical question-answering (MedQA) system. Specifically, we leverage the Llama3.1:70B model, a state-of-the-art LLM, in a multi-agent architecture to enhance performance on the MedQA dataset using zero-shot learning. Our method capitalizes on the model's inherent medical knowledge and reasoning capabilities, eliminating the need for additional training data. Experimental results show substantial performance gains over existing benchmark models, with improvements of 7% in both accuracy and F1-score across various medical QA tasks. Furthermore, we examine the model's interpretability and reliability in addressing complex medical queries. This research not only offers a robust solution for medical question answering but also establishes a foundation for broader applications of LLMs in the medical domain.

Key facts. Cited by 31 papers in the map (data through 7 Oct 2026). Builds on 30 of its 47 references that are in the map. First posted on arXiv 31 Dec 2024.

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30 of 47 references.

References · 30

  1. 2020Language Models are Few-Shot Learnerscited by 32,199
  2. 2023GPT-4 Technical Reportcited by 18,132
  3. 2019Exploring the Limits of Transfer Learning with a Unified Text-to-Text Transformercited by 14,491
  4. 2024The Llama 3 Herd of Modelscited by 14,192
  5. 2022Chain-of-Thought Prompting Elicits Reasoning in Large Language Modelscited by 12,302
  6. 2023Efficient Memory Management for Large Language Model Serving with PagedAttentioncited by 5,767
  7. 2022Self-Consistency Improves Chain of Thought Reasoning in Language Modelscited by 5,601
  8. 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,324
  9. 2024Large Language Model based Multi-Agents: A Survey of Progress and Challengescited by 752
  10. 2021Pre-Trained Models: Past, Present and Futurecited by 319
  11. 2023MedAgents: Large Language Models as Collaborators for Zero-shot Medical Reasoningcited by 311
  12. 2023Large language models in healthcare and medical domain: A reviewcited by 126
18 more
  1. 2023A Survey of Large Language Models in Medicine: Progress, Application, and Challengecited by 123
  2. 2024LLM-based Multi-Agent Reinforcement Learning: Current and Future Directionscited by 67
  3. 2024Med42 -- Evaluating Fine-Tuning Strategies for Medical LLMs: Full-Parameter vs. Parameter-Efficient Approachescited by 51
  4. 2024ClinicalAgent: Clinical Trial Multi-Agent System with Large Language Model-based Reasoningcited by 31
  5. 2024Multi-Agent VQA: Exploring Multi-Agent Foundation Models in Zero-Shot Visual Question Answeringcited by 15
  6. 2024UU-Mamba: Uncertainty-aware U-Mamba for Cardiac Image Segmentationcited by 15
  7. 2022Distributionally Robust Survival Analysis: A Novel Fairness Loss Without Demographicscited by 14
  8. 2024Fairness in Survival Analysis with Distributionally Robust Optimizationcited by 13
  9. 2024Robust COVID-19 Detection in CT Images with CLIPcited by 12
  10. 2024Robustly Optimized Deep Feature Decoupling Network for Fatty Liver Diseases Detectioncited by 11
  11. 2023UMedNeRF: Uncertainty-aware Single View Volumetric Rendering for Medical Neural Radiance Fieldscited by 10
  12. 2024Uncertainty-Aware Explainable Recommendation with Large Language Modelscited by 10
  13. 2024MedLM: Exploring Language Models for Medical Question Answering Systemscited by 6
  14. 2024Artificial Intelligence in Image-based Cardiovascular Disease Analysiscited by 6
  15. 2024An Explainable Non-local Network for COVID-19 Diagnosiscited by 5
  16. 2024Challenge Summary U-MedSAM: Uncertainty-aware MedSAM for Medical Image Segmentationcited by 5
  17. 2024An Uncertainty-Aware Generalization Framework for Cardiovascular Image Segmentationcited by 3
  18. 2024AI Managed Emergency Documentation with a Pretrained Modelcited by 2

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2025: 16; 2026: 15.

31 papers.

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  1. 2025In-the-Flow Agentic System Optimization for Effective Planning and Tool Usecited by 67
  2. 2025Latent Collaboration in Multi-Agent Systemscited by 67
  3. 2026MedDialogRubrics: A Comprehensive Benchmark and Evaluation Framework for Multi-turn Medical Consultations in Large Language Modelscited by 12
  4. 2026MedMO: Grounding and Understanding Multimodal Large Language Model for Medical Imagescited by 12
  5. 2026Recursive Multi-Agent Systemscited by 10
  6. 2026The Vision Wormhole: Latent-Space Communication in Heterogeneous Multi-Agent Systemscited by 8
  7. 2025Tiered Agentic Oversight: A Hierarchical Multi-Agent System for Healthcare Safetycited by 7
  8. 2025Improving Generalization of Medical Image Registration Foundation Modelcited by 6
  9. 2025MedChat: A Multi-Agent Framework for Multimodal Diagnosis with Large Language Modelscited by 5
  10. 2026TodyComm: Task-Oriented Dynamic Communication for Multi-Round LLM-based Multi-Agent Systemcited by 5
  11. 2025Robust Fairness Vision-Language Learning for Medical Image Analysiscited by 4
  12. 2025Beyond GeneGPT: A Multi-Agent Architecture with Open-Source LLMs for Enhanced Genomic Question Answeringcited by 3
19 more
  1. 2026When Planning Fails Despite Correct Execution: On Epistemic Calibration for LLM-Based Multi-Agent Systemscited by 3
  2. 2025ClinKD: Cross-Modal Clinical Knowledge Distiller For Multi-Task Medical Imagescited by 2
  3. 2025CaresAI at BioCreative IX Track 1 -- LLM for Biomedical QAcited by 1
  4. 2025BanglaMedQA and BanglaMMedBench: Evaluating Retrieval-Augmented Generation Strategies for Bangla Biomedical Question Answeringcited by 1
  5. 2025MedBayes-Lite: A Clinical Uncertainty Governance Layer for Risk-Aware Medical Decision Supportcited by 1
  6. 2026SoK: Privacy-aware LLM in Healthcare: Threat Model, Privacy Techniques, Challenges and Recommendationscited by 1
  7. 2026TATRA: Training-Free Instance-Adaptive Prompting Through Rephrasing and Aggregationcited by 1
  8. 2025Exploring the Role of Knowledge Graph-Based RAG in Japanese Medical Question Answering with Small-Scale LLMscited by 0
  9. 2025Retrieval Augmented Large Language Model System for Comprehensive Drug Contraindicationscited by 0
  10. 2025SparseDoctor: Towards Efficient Chat Doctor with Mixture of Experts Enhanced Large Language Modelscited by 0
  11. 2025CURE: Confidence-driven Unified Reasoning Ensemble Framework for Medical Question Answeringcited by 0
  12. 2025SOLVE-Med: Specialized Orchestration for Leading Vertical Experts across Medical Specialtiescited by 0
  13. 2026Self-MedRAG: a Self-Reflective Hybrid Retrieval-Augmented Generation Framework for Reliable Medical Question Answeringcited by 0
  14. 2026MediHive: A Decentralized Agent Collective for Medical Reasoningcited by 0
  15. 2026Answering the Wrong Question: Reasoning Trace Inversion for Abstention in LLMscited by 0
  16. 2026Robust Multi-Source Covid-19 Detection in CT Imagescited by 0
  17. 2026APCD: Adaptive Path-Contrastive Decoding for Reliable Large Language Model Generationcited by 0
  18. 2026Improving Answer Extraction in Context-based Question Answering Systems Using LLMscited by 0
  19. 2026Towards Direct Latent-Space Synthesis for Parallel Branches in LLM-Agent Workflowscited by 0

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  1. 2026Let LLMs Judge Each Other: Multi-Agent Peer-Reviewed Reasoning for Medical Question Answering
  2. 2026A Multi-Agent Framework for Medical AI: Leveraging Fine-Tuned GPT, LLaMA, and DeepSeek R1 for Evidence-Based and Bias-Aware Clinical Query Processing
  3. 2025Structured Outputs Enable General-Purpose LLMs to be Medical Experts
  4. 2025Collaboration among Multiple Large Language Models for Medical Question Answering
  5. 2025Optimizing Medical Question-Answering Systems: A Comparative Study of Fine-Tuned and Zero-Shot Large Language Models with RAG Framework
  6. 2024A Survey for Large Language Models in Biomedicine
  7. 2025AMANDA: Agentic Medical Knowledge Augmentation for Data-Efficient Medical Visual Question Answering
  8. 2025MedBioLM: Optimizing Medical and Biological QA with Fine-Tuned Large Language Models and Retrieval-Augmented Generation