mlsanityData to 7 Oct 2026

MedDialogRubrics: A Comprehensive Benchmark and Evaluation Framework for Multi-turn Medical Consultations in Large Language Models

arXiv 2601.03023 ↗First posted 6 Jan 2026cs.CL cs.HCcited by 12

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Abstract (arXiv)

Medical conversational AI (AI) plays a pivotal role in the development of safer and more effective medical dialogue systems. However, existing benchmarks and evaluation frameworks for assessing the information-gathering and diagnostic reasoning abilities of medical large language models (LLMs) have not been rigorously evaluated. To address these gaps, we present MedDialogRubrics, a novel benchmark comprising 5,200 synthetically constructed patient cases and over 60,000 fine-grained evaluation rubrics generated by LLMs and subsequently refined by clinical experts, specifically designed to assess the multi-turn diagnostic capabilities of LLM. Our framework employs a multi-agent system to synthesize realistic patient records and chief complaints from underlying disease knowledge without accessing real-world electronic health records, thereby mitigating privacy and data-governance concerns. We design a robust Patient Agent that is limited to a set of atomic medical facts and augmented with a dynamic guidance mechanism that continuously detects and corrects hallucinations throughout the dialogue, ensuring internal coherence and clinical plausibility of the simulated cases. Furthermore, we propose a structured LLM-based and expert-annotated rubric-generation pipeline that retrieves Evidence-Based Medicine (EBM) guidelines and utilizes the reject sampling to derive a prioritized set of rubric items ("must-ask" items) for each case. We perform a comprehensive evaluation of state-of-the-art models and demonstrate that, across multiple assessment dimensions, current models face substantial challenges. Our results indicate that improving medical dialogue will require advances in dialogue management architectures, not just incremental tuning of the base-model.

Key facts. Cited by 12 papers in the map (data through 7 Oct 2026). Builds on 18 of its 36 references that are in the map. First posted on arXiv 6 Jan 2026.

Builds on

18 of 36 references.

References · 18

  1. 2022Large Language Models Encode Clinical Knowledgecited by 1,807
  2. 2022MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answeringcited by 525
  3. 2025HealthBench: Evaluating Large Language Models Towards Improved Human Healthcited by 385
  4. 2023Towards Expert-Level Medical Question Answering with Large Language Modelscited by 382
  5. 2024AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environmentscited by 215
  6. 2025Qwen2.5-1M Technical Reportcited by 158
  7. 2024MediQ: Question-Asking LLMs and a Benchmark for Reliable Interactive Clinical Reasoningcited by 145
  8. 2024AI Hospital: Benchmarking Large Language Models in a Multi-agent Medical Interaction Simulatorcited by 99
  9. 2025MedHELM: Holistic Evaluation of Large Language Models for Medical Taskscited by 60
  10. 2025Self-Evolving Multi-Agent Simulations for Realistic Clinical Interactionscited by 40
  11. 2024Automatic Interactive Evaluation for Large Language Models with State Aware Patient Simulatorcited by 36
  12. 2024LLM-MedQA: Enhancing Medical Question Answering through Case Studies in Large Language Modelscited by 31
6 more
  1. 2024PATIENT-Psi: Using Large Language Models to Simulate Patients for Training Mental Health Professionalscited by 19
  2. 20253MDBench: Medical Multimodal Multi-agent Dialogue Benchmarkcited by 16
  3. 2023LLM-Mini-CEX: Automatic Evaluation of Large Language Model for Diagnostic Conversationcited by 14
  4. 2023An Automatic Evaluation Framework for Multi-turn Medical Consultations Capabilities of Large Language Modelscited by 13
  5. 2025The Dialogue That Heals: A Comprehensive Evaluation of Doctor Agents' Inquiry Capabilitycited by 10
  6. 2025Dynamic Affective Memory Management for Personalized LLM Agentscited by 7

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Citing papers per year: 2026: 12.

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  1. 2025Dialogue is Better Than Monologue: Instructing Medical LLMs via Strategical Conversations
  2. 2025AutoMedic: An Automated Evaluation Framework for Clinical Conversational Agents with Medical Dataset Grounding
  3. 2025Advancing Conversational Diagnostic AI with Multimodal Reasoning
  4. 2025MedBrowseComp: Benchmarking Medical Deep Research and Computer Use
  5. 2025ClinDEF: A Dynamic Evaluation Framework for Large Language Models in Clinical Reasoning
  6. 2023Large Language Models Illuminate a Progressive Pathway to Artificial Healthcare Assistant: A Review
  7. 2026Towards Reliable Medical LLMs: Benchmarking and Enhancing Confidence Estimation of Large Language Models in Medical Consultation
  8. 2026A prospective clinical feasibility study of a conversational diagnostic AI in an ambulatory primary care clinic