SurgBox: Agent-Driven Operating Room Sandbox with Surgery Copilot
On the map: LLM agents and tool use → Medical and scientific domain agents
Abstract (arXiv)
Surgical interventions, particularly in neurology, represent complex and high-stakes scenarios that impose substantial cognitive burdens on surgical teams. Although deliberate education and practice can enhance cognitive capabilities, surgical training opportunities remain limited due to patient safety concerns. To address these cognitive challenges in surgical training and operation, we propose SurgBox, an agent-driven sandbox framework to systematically enhance the cognitive capabilities of surgeons in immersive surgical simulations. Specifically, our SurgBox leverages large language models (LLMs) with tailored Retrieval-Augmented Generation (RAG) to authentically replicate various surgical roles, enabling realistic training environments for deliberate practice. In particular, we devise Surgery Copilot, an AI-driven assistant to actively coordinate the surgical information stream and support clinical decision-making, thereby diminishing the cognitive workload of surgical teams during surgery. By incorporating a novel Long-Short Memory mechanism, our Surgery Copilot can effectively balance immediate procedural assistance with comprehensive surgical knowledge. Extensive experiments using real neurosurgical procedure records validate our SurgBox framework in both enhancing surgical cognitive capabilities and supporting clinical decision-making. By providing an integrated solution for training and operational support to address cognitive challenges, our SurgBox framework advances surgical education and practice, potentially transforming surgical outcomes and healthcare quality. The code is available at https://github.com/franciszchen/SurgBox.
Key facts. Cited by 6 papers in the map (data through 14 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 19 of its 30 references that are in the map. First posted on arXiv 6 Dec 2024.
Builds on
19 of 30 references.
Closest ancestors · 1
Same direction, newest first
Other references · 18
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Built on by
Citing papers per year: 2025: 4; 2026: 2.
6 papers.
- 2025A Survey of LLM-based Agents in Medicine: How far are we from Baymax?cited by 85
- 2025How Far Are Surgeons from Surgical World Models? A Pilot Study on Zero-shot Surgical Video Generation with Expert Assessmentcited by 11
- 2025SurgVisAgent: Multimodal Agentic Model for Versatile Surgical Visual Enhancementcited by 1
- 2026Agentic AI in Healthcare & Medicine: A Seven-Dimensional Taxonomy for Empirical Evaluation of LLM-based Agentscited by 1
- 2026Speak, Segment, Track, Navigate: An Interactive System for Video-Guided Skull-Base Surgerycited by 1
- 2025Capacity Matters: a Proof-of-Concept for Transformer Memorization on Real-World Datacited by 0
- 2026Speak, Segment, Track, Navigate: An Interactive System for Video-Guided Skull-Base Surgery17 Mar 2026
- 2026Agentic AI in Healthcare & Medicine: A Seven-Dimensional Taxonomy for Empirical Evaluation of LLM-based Agents4 Feb 2026
- 2025How Far Are Surgeons from Surgical World Models? A Pilot Study on Zero-shot Surgical Video Generation with Expert Assessment3 Nov 2025
- 2025SurgVisAgent: Multimodal Agentic Model for Versatile Surgical Visual Enhancement3 Jul 2025
- 2025Capacity Matters: a Proof-of-Concept for Transformer Memorization on Real-World Data17 Jun 2025
- 2025A Survey of LLM-based Agents in Medicine: How far are we from Baymax?16 Feb 2025
Similar, not cited
Close in wording, no citation either way
- 2026SURGENT: A Surgical Multi-Agent Assistance System Across the Perioperative Workflow
- 2026SurgSigma: A Spectrum of Large-Scale Multimodal Data and Foundation Models for Surgical Intelligence
- 2025SurgRAW: Multi-Agent Workflow with Chain of Thought Reasoning for Robotic Surgical Video Analysis
- 2025Surgical AI Copilot: Energy-Based Fourier Gradient Low-Rank Adaptation for Surgical LLM Agent Reasoning and Planning
- 2026SurgOnAir: Hierarchy-Aware Real-Time Surgical Video Commentary
- 2025SurgVLM: A Large Vision-Language Model and Systematic Evaluation Benchmark for Surgical Intelligence
- 2025Voice-Interactive Surgical Agent for Multimodal Patient Data Control
- 2025Specialized Foundation Models for Intelligent Operating Rooms