H-vmunet: High-order Vision Mamba UNet for Medical Image Segmentation
On the map: State-space sequence models (S4, Mamba) → Mamba for medical image analysis
Abstract (arXiv)
In the field of medical image segmentation, variant models based on Convolutional Neural Networks (CNNs) and Visual Transformers (ViTs) as the base modules have been very widely developed and applied. However, CNNs are often limited in their ability to deal with long sequences of information, while the low sensitivity of ViTs to local feature information and the problem of secondary computational complexity limit their development. Recently, the emergence of state-space models (SSMs), especially 2D-selective-scan (SS2D), has had an impact on the longtime dominance of traditional CNNs and ViTs as the foundational modules of visual neural networks. In this paper, we extend the adaptability of SS2D by proposing a High-order Vision Mamba UNet (H-vmunet) for medical image segmentation. Among them, the proposed High-order 2D-selective-scan (H-SS2D) progressively reduces the introduction of redundant information during SS2D operations through higher-order interactions. In addition, the proposed Local-SS2D module improves the learning ability of local features of SS2D at each order of interaction. We conducted comparison and ablation experiments on three publicly available medical image datasets (ISIC2017, Spleen, and CVC-ClinicDB), and the results all demonstrate the strong competitiveness of H-vmunet in medical image segmentation tasks. The code is available from https://github.com/wurenkai/H-vmunet .
Key facts. Cited by 35 papers in the map (data through 14 Oct 2026). Placed in Mamba for medical image analysis, one of 10 directions in State-space sequence models (S4, Mamba). Builds on 25 of its 41 references that are in the map. First posted on arXiv 20 Mar 2024.
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25 of 41 references.
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Other references · 24
- 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 30,186
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,713
- 2014Fully Convolutional Networks for Semantic Segmentationcited by 4,859
- 2023Mamba: Linear-Time Sequence Modeling with Selective State Spacescited by 4,718
- 2020Training data-efficient image transformers & distillation through attentioncited by 4,586
- 2022A ConvNet for the 2020scited by 3,579
- 2021Efficiently Modeling Long Sequences with Structured State Spacescited by 2,465
- 2018Attention U-Net: Learning Where to Look for the Pancreascited by 1,435
- 2021Swin-Unet: Unet-like Pure Transformer for Medical Image Segmentationcited by 1,222
- 2024Vision Mamba: Efficient Visual Representation Learning with Bidirectional State Space Modelcited by 1,056
- 2024VMamba: Visual State Space Modelcited by 969
- 2019Skin Lesion Analysis Toward Melanoma Detection 2018: A Challenge Hosted by the International Skin Imaging Collaboration (ISIC)cited by 669
12 more
- 2021The Medical Segmentation Decathloncited by 628
- 2021Combining Recurrent, Convolutional, and Continuous-time Models with Linear State-Space Layerscited by 608
- 2017Skin Lesion Analysis Toward Melanoma Detection: A Challenge at the 2017 International Symposium on Biomedical Imaging (ISBI), Hosted by the International Skin Imaging Collaboration (ISIC)cited by 549
- 2021Global Filter Networks for Image Classificationcited by 260
- 2022HorNet: Efficient High-Order Spatial Interactions with Recursive Gated Convolutionscited by 103
- 2021Automatic Polyp Segmentation via Multi-scale Subtraction Networkcited by 77
- 2022MALUNet: A Multi-Attention and Light-weight UNet for Skin Lesion Segmentationcited by 59
- 2022TransNorm: Transformer Provides a Strong Spatial Normalization Mechanism for a Deep Segmentation Modelcited by 34
- 2023Devil is in Channels: Contrastive Single Domain Generalization for Medical Image Segmentationcited by 30
- 2023U-Net v2: Rethinking the Skip Connections of U-Net for Medical Image Segmentationcited by 23
- 2022Attention Swin U-Net: Cross-Contextual Attention Mechanism for Skin Lesion Segmentationcited by 21
- 2023Only Positive Cases: 5-fold High-order Attention Interaction Model for Skin Segmentation Derived Classificationcited by 1
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Citing papers per year: 2024: 16; 2025: 7; 2026: 12.
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- 2026CS-MUNet: A Channel-Spatial Dual-Stream Mamba Network for Multi-Organ Segmentation20 Mar 2026
- 2026ARIADNE: A Perception-Reasoning Synergy Framework for Trustworthy Coronary Angiography Analysis19 Mar 2026
- 2026SpectralMamba-UNet: Frequency-Disentangled State Space Modeling for Texture-Structure Consistent Medical Image Segmentation26 Feb 2026
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- 2024SkinMamba: A Precision Skin Lesion Segmentation Architecture with Cross-Scale Global State Modeling and Frequency Boundary Guidance17 Sep 2024
- 2024OCTAMamba: A State-Space Model Approach for Precision OCTA Vasculature Segmentation12 Sep 2024
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- 2024Vision Mamba: A Comprehensive Survey and Taxonomycited by 54
- 2024A Survey on Visual Mambacited by 50
- 2024UltraLight VM-UNet: Parallel Vision Mamba Significantly Reduces Parameters for Skin Lesion Segmentationcited by 45
- 2024DGMamba: Domain Generalization via Generalized State Space Modelcited by 21
- 2024Mamba in Vision: A Comprehensive Survey of Techniques and Applicationscited by 18
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- 2025A Comprehensive Analysis of Mamba for 3D Volumetric Medical Image Segmentationcited by 4
- 2026MambaLiteUNet: Cross-Gated Adaptive Feature Fusion for Robust Skin Lesion Segmentationcited by 4
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- 2025ASP-VMUNet: Atrous Shifted Parallel Vision Mamba U-Net for Skin Lesion Segmentationcited by 1
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- 2026MambaADv2: Evolving Duality-enhanced State Space Model for Unsupervised Anomaly Detection22 Jun 2026
- 20263D Segment Anything Model with Visual Mamba for Diagnosing Placenta Accreta Spectrum30 May 2026
- 2026MambaLiteUNet: Cross-Gated Adaptive Feature Fusion for Robust Skin Lesion Segmentation22 Apr 2026
- 2026CS-MUNet: A Channel-Spatial Dual-Stream Mamba Network for Multi-Organ Segmentation20 Mar 2026
- 2026SpectralMamba-UNet: Frequency-Disentangled State Space Modeling for Texture-Structure Consistent Medical Image Segmentation26 Feb 2026
- 2026Is Mamba Reliable for Medical Imaging?16 Feb 2026
- 2025WDFFU-Mamba: A Wavelet-guided Dual-attention Feature Fusion Mamba for Breast Tumor Segmentation in Ultrasound Images19 Dec 2025
- 2025Diversity-enhanced Collaborative Mamba for Semi-supervised Medical Image Segmentation19 Aug 2025
- 2025Prompt-Guided Dual-Path UNet with Mamba for Medical Image Segmentation25 Mar 2025
- 2025ASP-VMUNet: Atrous Shifted Parallel Vision Mamba U-Net for Skin Lesion Segmentation25 Mar 2025
12 newest of 24 All 24 (JSON)
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- 2024Test-time generative augmentation for medical image segmentationcited by 6
- 2024SkinMamba: A Precision Skin Lesion Segmentation Architecture with Cross-Scale Global State Modeling and Frequency Boundary Guidancecited by 4
- 2024OCTAMamba: A State-Space Model Approach for Precision OCTA Vasculature Segmentationcited by 3
- 2026ARIADNE: A Perception-Reasoning Synergy Framework for Trustworthy Coronary Angiography Analysiscited by 0
- 2026PGR-Net: Prior-Guided ROI Reasoning Network for Brain Tumor MRI Segmentationcited by 0
- 2026Unifying VLM-Guided Flow Matching and Spectral Anomaly Detection for Interpretable Veterinary Diagnosiscited by 0
- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigmscited by 0
- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigms29 Jun 2026
- 2026Unifying VLM-Guided Flow Matching and Spectral Anomaly Detection for Interpretable Veterinary Diagnosis7 Apr 2026
- 2026PGR-Net: Prior-Guided ROI Reasoning Network for Brain Tumor MRI Segmentation23 Mar 2026
- 2026ARIADNE: A Perception-Reasoning Synergy Framework for Trustworthy Coronary Angiography Analysis19 Mar 2026
- 2025RWKV-UNet: Improving UNet with Long-Range Cooperation for Effective Medical Image Segmentation14 Jan 2025
- 2024SkinMamba: A Precision Skin Lesion Segmentation Architecture with Cross-Scale Global State Modeling and Frequency Boundary Guidance17 Sep 2024
- 2024OCTAMamba: A State-Space Model Approach for Precision OCTA Vasculature Segmentation12 Sep 2024
- 2024Test-time generative augmentation for medical image segmentation25 Jun 2024
- 2024State Space Model for New-Generation Network Alternative to Transformers: A Survey15 Apr 2024
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