VM-UNET-V2 Rethinking Vision Mamba UNet for Medical Image Segmentation
On the map: State-space sequence models (S4, Mamba) → Mamba for medical image analysis
Abstract (arXiv)
In the field of medical image segmentation, models based on both CNN and Transformer have been thoroughly investigated. However, CNNs have limited modeling capabilities for long-range dependencies, making it challenging to exploit the semantic information within images fully. On the other hand, the quadratic computational complexity poses a challenge for Transformers. Recently, State Space Models (SSMs), such as Mamba, have been recognized as a promising method. They not only demonstrate superior performance in modeling long-range interactions, but also preserve a linear computational complexity. Inspired by the Mamba architecture, We proposed Vison Mamba-UNetV2, the Visual State Space (VSS) Block is introduced to capture extensive contextual information, the Semantics and Detail Infusion (SDI) is introduced to augment the infusion of low-level and high-level features. We conduct comprehensive experiments on the ISIC17, ISIC18, CVC-300, CVC-ClinicDB, Kvasir, CVC-ColonDB and ETIS-LaribPolypDB public datasets. The results indicate that VM-UNetV2 exhibits competitive performance in medical image segmentation tasks. Our code is available at https://github.com/nobodyplayer1/VM-UNetV2.
Key facts. Cited by 39 papers in the map (data through 7 Oct 2026). Placed in Mamba for medical image analysis, one of 10 directions in State-space sequence models (S4, Mamba). Builds on 20 of its 27 references that are in the map. First posted on arXiv 14 Mar 2024.
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20 of 27 references.
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Other references · 19
- 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
- 2023Mamba: Linear-Time Sequence Modeling with Selective State Spacescited by 4,616
- 2017MobileNets: Efficient Convolutional Neural Networks for Mobile Vision Applicationscited by 3,827
- 2018Encoder-Decoder with Atrous Separable Convolution for Semantic Image Segmentationcited by 3,210
- 2018CBAM: Convolutional Block Attention Modulecited by 2,463
- 2020GLU Variants Improve Transformercited by 1,724
- 2021TransUNet: Transformers Make Strong Encoders for Medical Image Segmentationcited by 1,552
- 2018UNet++: A Nested U-Net Architecture for Medical Image Segmentationcited by 1,518
- 20163D U-Net: Learning Dense Volumetric Segmentation from Sparse Annotationcited by 1,471
- 2018Attention U-Net: Learning Where to Look for the Pancreascited by 1,420
- 2015Multi-Scale Context Aggregation by Dilated Convolutionscited by 1,128
- 2024VMamba: Visual State Space Modelcited by 955
7 more
- 2018Path Aggregation Network for Instance Segmentationcited by 796
- 2021TransFuse: Fusing Transformers and CNNs for Medical Image Segmentationcited by 258
- 2021Shallow Attention Network for Polyp Segmentationcited by 107
- 2022MALUNet: A Multi-Attention and Light-weight UNet for Skin Lesion Segmentationcited by 59
- 2022TransDeepLab: Convolution-Free Transformer-based DeepLab v3+ for Medical Image Segmentationcited by 43
- 2022TransNorm: Transformer Provides a Strong Spatial Normalization Mechanism for a Deep Segmentation Modelcited by 34
- 2023U-Net v2: Rethinking the Skip Connections of U-Net for Medical Image Segmentationcited by 23
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Citing papers per year: 2024: 17; 2025: 12; 2026: 10.
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- 2024Fusion-Mamba for Cross-modality Object Detectioncited by 67
- 2024State Space Model for New-Generation Network Alternative to Transformers: A Surveycited by 59
- 2024Vision Mamba: A Comprehensive Survey and Taxonomycited by 53
- 2024A Survey on Visual Mambacited by 50
- 2024UltraLight VM-UNet: Parallel Vision Mamba Significantly Reduces Parameters for Skin Lesion Segmentationcited by 45
- 2024A Comprehensive Survey of Mamba Architectures for Medical Image Analysis: Classification, Segmentation, Restoration and Beyondcited by 16
- 2025AVS-Mamba: Exploring Temporal and Multi-modal Mamba for Audio-Visual Segmentationcited by 15
- 2024ProMamba: Prompt-Mamba for polyp segmentationcited by 12
- 2024Rotate to Scan: UNet-like Mamba with Triplet SSM Module for Medical Image Segmentationcited by 12
- 2024xLSTM-UNet can be an Effective 2D & 3D Medical Image Segmentation Backbone with Vision-LSTM (ViL) better than its Mamba Counterpartcited by 12
- 2025Mamba-Sea: A Mamba-based Framework with Global-to-Local Sequence Augmentation for Generalizable Medical Image Segmentationcited by 7
- 2024HMT-UNet: A hybird Mamba-Transformer Vision UNet for Medical Image Segmentationcited by 6
27 more
- 2024Topology-aware Mamba for Crack Segmentation in Structurescited by 6
- 2024MUCM-Net: A Mamba Powered UCM-Net for Skin Lesion Segmentationcited by 5
- 2024SkinMamba: A Precision Skin Lesion Segmentation Architecture with Cross-Scale Global State Modeling and Frequency Boundary Guidancecited by 4
- 2025A Comprehensive Analysis of Mamba for 3D Volumetric Medical Image Segmentationcited by 4
- 2026MambaLiteUNet: Cross-Gated Adaptive Feature Fusion for Robust Skin Lesion Segmentationcited by 4
- 2025A Reverse Mamba Attention Network for Pathological Liver Segmentationcited by 3
- 2024MLLA-UNet: Mamba-like Linear Attention in an Efficient U-Shape Model for Medical Image Segmentationcited by 2
- 2024Venturing into Uncharted Waters: The Navigation Compass from Transformer to Mambacited by 1
- 2025BS-Mamba for Black-Soil Area Detection On the Qinghai-Tibetan Plateaucited by 1
- 2025ASP-VMUNet: Atrous Shifted Parallel Vision Mamba U-Net for Skin Lesion Segmentationcited by 1
- 2025UNet with Self-Adaptive Mamba-Like Attention and Causal-Resonance Learning for Medical Image Segmentationcited by 1
- 2025CMFDNet: Cross-Mamba and Feature Discovery Network for Polyp Segmentationcited by 1
- 2024LiteNeXt: A Novel Lightweight ConvMixer-based Model with Self-embedding Representation Parallel for Medical Image Segmentationcited by 0
- 2024When Mamba Meets xLSTM: An Efficient and Precise Method with the xLSTM-VMUNet Model for Skin lesion Segmentationcited by 0
- 2025SSNet: Saliency Prior and State Space Model-based Network for Salient Object Detection in RGB-D Imagescited by 0
- 2025Prompt-Guided Dual-Path UNet with Mamba for Medical Image Segmentationcited by 0
- 2025MambaCAFU: Hybrid Multi-Scale and Multi-Attention Model with Mamba-Based Fusion for Medical Image Segmentationcited by 0
- 2025WDFFU-Mamba: A Wavelet-guided Dual-attention Feature Fusion Mamba for Breast Tumor Segmentation in Ultrasound Imagescited by 0
- 2026DSVM-UNet : Enhancing VM-UNet with Dual Self-distillation for Medical Image Segmentationcited by 0
- 2026SGDC: Structurally-Guided Dynamic Convolution for Medical Image Segmentationcited by 0
- 2026CS-MUNet: A Channel-Spatial Dual-Stream Mamba Network for Multi-Organ Segmentationcited by 0
- 20263D Segment Anything Model with Visual Mamba for Diagnosing Placenta Accreta Spectrumcited by 0
- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigmscited by 0
- 2026A Unified Benchmark of Deep Learning Models for Multi-task 3D Brain Tumor Segmentation from Magnetic Resonance Imagingcited by 0
- 2026CSG-Mamba: A Convolutional Scoring Gating Vision State Space Network for Endoscopic Polyp Segmentationcited by 0
- 2026MaLViL: Multi-axis Low-rank Vision-LSTM for Medical Image Segmentationcited by 0
- 2026FU-Mamba: A Frequency-Enhanced Dynamic Scanning Framework for Oralscan Image Segmentationcited by 0
- 2026FU-Mamba: A Frequency-Enhanced Dynamic Scanning Framework for Oralscan Image Segmentation27 Aug 2026
- 2026MaLViL: Multi-axis Low-rank Vision-LSTM for Medical Image Segmentation18 Aug 2026
- 2026CSG-Mamba: A Convolutional Scoring Gating Vision State Space Network for Endoscopic Polyp Segmentation14 Aug 2026
- 2026A Unified Benchmark of Deep Learning Models for Multi-task 3D Brain Tumor Segmentation from Magnetic Resonance Imaging30 Jul 2026
- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigms29 Jun 2026
- 20263D Segment Anything Model with Visual Mamba for Diagnosing Placenta Accreta Spectrum30 May 2026
- 2026MambaLiteUNet: Cross-Gated Adaptive Feature Fusion for Robust Skin Lesion Segmentation22 Apr 2026
- 2026CS-MUNet: A Channel-Spatial Dual-Stream Mamba Network for Multi-Organ Segmentation20 Mar 2026
- 2026SGDC: Structurally-Guided Dynamic Convolution for Medical Image Segmentation26 Feb 2026
- 2026DSVM-UNet : Enhancing VM-UNet with Dual Self-distillation for Medical Image Segmentation27 Jan 2026
- 2025WDFFU-Mamba: A Wavelet-guided Dual-attention Feature Fusion Mamba for Breast Tumor Segmentation in Ultrasound Images19 Dec 2025
- 2025MambaCAFU: Hybrid Multi-Scale and Multi-Attention Model with Mamba-Based Fusion for Medical Image Segmentation4 Oct 2025
27 more
- 2025CMFDNet: Cross-Mamba and Feature Discovery Network for Polyp Segmentation25 Aug 2025
- 2025UNet with Self-Adaptive Mamba-Like Attention and Causal-Resonance Learning for Medical Image Segmentation21 May 2025
- 2025Mamba-Sea: A Mamba-based Framework with Global-to-Local Sequence Augmentation for Generalizable Medical Image Segmentation24 Apr 2025
- 2025Prompt-Guided Dual-Path UNet with Mamba for Medical Image Segmentation25 Mar 2025
- 2025ASP-VMUNet: Atrous Shifted Parallel Vision Mamba U-Net for Skin Lesion Segmentation25 Mar 2025
- 2025A Comprehensive Analysis of Mamba for 3D Volumetric Medical Image Segmentation25 Mar 2025
- 2025BS-Mamba for Black-Soil Area Detection On the Qinghai-Tibetan Plateau16 Mar 2025
- 2025SSNet: Saliency Prior and State Space Model-based Network for Salient Object Detection in RGB-D Images4 Mar 2025
- 2025A Reverse Mamba Attention Network for Pathological Liver Segmentation23 Feb 2025
- 2025AVS-Mamba: Exploring Temporal and Multi-modal Mamba for Audio-Visual Segmentation14 Jan 2025
- 2024When Mamba Meets xLSTM: An Efficient and Precise Method with the xLSTM-VMUNet Model for Skin lesion Segmentation14 Nov 2024
- 2024MLLA-UNet: Mamba-like Linear Attention in an Efficient U-Shape Model for Medical Image Segmentation31 Oct 2024
- 2024Topology-aware Mamba for Crack Segmentation in Structures25 Oct 2024
- 2024A Comprehensive Survey of Mamba Architectures for Medical Image Analysis: Classification, Segmentation, Restoration and Beyond3 Oct 2024
- 2024SkinMamba: A Precision Skin Lesion Segmentation Architecture with Cross-Scale Global State Modeling and Frequency Boundary Guidance17 Sep 2024
- 2024HMT-UNet: A hybird Mamba-Transformer Vision UNet for Medical Image Segmentation21 Aug 2024
- 2024xLSTM-UNet can be an Effective 2D & 3D Medical Image Segmentation Backbone with Vision-LSTM (ViL) better than its Mamba Counterpart1 Jul 2024
- 2024Venturing into Uncharted Waters: The Navigation Compass from Transformer to Mamba24 Jun 2024
- 2024MUCM-Net: A Mamba Powered UCM-Net for Skin Lesion Segmentation24 May 2024
- 2024Vision Mamba: A Comprehensive Survey and Taxonomy7 May 2024
- 2024A Survey on Visual Mamba24 Apr 2024
- 2024State Space Model for New-Generation Network Alternative to Transformers: A Survey15 Apr 2024
- 2024Fusion-Mamba for Cross-modality Object Detection14 Apr 2024
- 2024LiteNeXt: A Novel Lightweight ConvMixer-based Model with Self-embedding Representation Parallel for Medical Image Segmentation4 Apr 2024
- 2024UltraLight VM-UNet: Parallel Vision Mamba Significantly Reduces Parameters for Skin Lesion Segmentation29 Mar 2024
- 2024Rotate to Scan: UNet-like Mamba with Triplet SSM Module for Medical Image Segmentation26 Mar 2024
- 2024ProMamba: Prompt-Mamba for polyp segmentation20 Mar 2024
- 2024Fusion-Mamba for Cross-modality Object Detectioncited by 67
- 2024Vision Mamba: A Comprehensive Survey and Taxonomycited by 53
- 2024A Survey on Visual Mambacited by 50
- 2024UltraLight VM-UNet: Parallel Vision Mamba Significantly Reduces Parameters for Skin Lesion Segmentationcited by 45
- 2024A Comprehensive Survey of Mamba Architectures for Medical Image Analysis: Classification, Segmentation, Restoration and Beyondcited by 16
- 2025AVS-Mamba: Exploring Temporal and Multi-modal Mamba for Audio-Visual Segmentationcited by 15
- 2024ProMamba: Prompt-Mamba for polyp segmentationcited by 12
- 2024Rotate to Scan: UNet-like Mamba with Triplet SSM Module for Medical Image Segmentationcited by 12
- 2024xLSTM-UNet can be an Effective 2D & 3D Medical Image Segmentation Backbone with Vision-LSTM (ViL) better than its Mamba Counterpartcited by 12
- 2025Mamba-Sea: A Mamba-based Framework with Global-to-Local Sequence Augmentation for Generalizable Medical Image Segmentationcited by 7
- 2024HMT-UNet: A hybird Mamba-Transformer Vision UNet for Medical Image Segmentationcited by 6
- 2024Topology-aware Mamba for Crack Segmentation in Structurescited by 6
12 most cited of 29 All 29 (JSON)
- 2026FU-Mamba: A Frequency-Enhanced Dynamic Scanning Framework for Oralscan Image Segmentation27 Aug 2026
- 2026CSG-Mamba: A Convolutional Scoring Gating Vision State Space Network for Endoscopic Polyp Segmentation14 Aug 2026
- 20263D Segment Anything Model with Visual Mamba for Diagnosing Placenta Accreta Spectrum30 May 2026
- 2026MambaLiteUNet: Cross-Gated Adaptive Feature Fusion for Robust Skin Lesion Segmentation22 Apr 2026
- 2026CS-MUNet: A Channel-Spatial Dual-Stream Mamba Network for Multi-Organ Segmentation20 Mar 2026
- 2026DSVM-UNet : Enhancing VM-UNet with Dual Self-distillation for Medical Image Segmentation27 Jan 2026
- 2025WDFFU-Mamba: A Wavelet-guided Dual-attention Feature Fusion Mamba for Breast Tumor Segmentation in Ultrasound Images19 Dec 2025
- 2025MambaCAFU: Hybrid Multi-Scale and Multi-Attention Model with Mamba-Based Fusion for Medical Image Segmentation4 Oct 2025
- 2025UNet with Self-Adaptive Mamba-Like Attention and Causal-Resonance Learning for Medical Image Segmentation21 May 2025
- 2025Mamba-Sea: A Mamba-based Framework with Global-to-Local Sequence Augmentation for Generalizable Medical Image Segmentation24 Apr 2025
- 2025Prompt-Guided Dual-Path UNet with Mamba for Medical Image Segmentation25 Mar 2025
- 2025ASP-VMUNet: Atrous Shifted Parallel Vision Mamba U-Net for Skin Lesion Segmentation25 Mar 2025
12 newest of 29 All 29 (JSON)
- 2024State Space Model for New-Generation Network Alternative to Transformers: A Surveycited by 59
- 2024SkinMamba: A Precision Skin Lesion Segmentation Architecture with Cross-Scale Global State Modeling and Frequency Boundary Guidancecited by 4
- 2025BS-Mamba for Black-Soil Area Detection On the Qinghai-Tibetan Plateaucited by 1
- 2025CMFDNet: Cross-Mamba and Feature Discovery Network for Polyp Segmentationcited by 1
- 2024LiteNeXt: A Novel Lightweight ConvMixer-based Model with Self-embedding Representation Parallel for Medical Image Segmentationcited by 0
- 2025SSNet: Saliency Prior and State Space Model-based Network for Salient Object Detection in RGB-D Imagescited by 0
- 2026SGDC: Structurally-Guided Dynamic Convolution for Medical Image Segmentationcited by 0
- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigmscited by 0
- 2026A Unified Benchmark of Deep Learning Models for Multi-task 3D Brain Tumor Segmentation from Magnetic Resonance Imagingcited by 0
- 2026MaLViL: Multi-axis Low-rank Vision-LSTM for Medical Image Segmentationcited by 0
- 2026MaLViL: Multi-axis Low-rank Vision-LSTM for Medical Image Segmentation18 Aug 2026
- 2026A Unified Benchmark of Deep Learning Models for Multi-task 3D Brain Tumor Segmentation from Magnetic Resonance Imaging30 Jul 2026
- 2026APRIL-MedSeg: A Modular Medical Image Segmentation Toolbox Embracing Modern Paradigms29 Jun 2026
- 2026SGDC: Structurally-Guided Dynamic Convolution for Medical Image Segmentation26 Feb 2026
- 2025CMFDNet: Cross-Mamba and Feature Discovery Network for Polyp Segmentation25 Aug 2025
- 2025BS-Mamba for Black-Soil Area Detection On the Qinghai-Tibetan Plateau16 Mar 2025
- 2025SSNet: Saliency Prior and State Space Model-based Network for Salient Object Detection in RGB-D Images4 Mar 2025
- 2024SkinMamba: A Precision Skin Lesion Segmentation Architecture with Cross-Scale Global State Modeling and Frequency Boundary Guidance17 Sep 2024
- 2024State Space Model for New-Generation Network Alternative to Transformers: A Survey15 Apr 2024
- 2024LiteNeXt: A Novel Lightweight ConvMixer-based Model with Self-embedding Representation Parallel for Medical Image Segmentation4 Apr 2024
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