Guiding Masked Representation Learning to Capture Spatio-Temporal Relationship of Electrocardiogram
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Abstract (arXiv)
Electrocardiograms (ECG) are widely employed as a diagnostic tool for monitoring electrical signals originating from a heart. Recent machine learning research efforts have focused on the application of screening various diseases using ECG signals. However, adapting to the application of screening disease is challenging in that labeled ECG data are limited. Achieving general representation through self-supervised learning (SSL) is a well-known approach to overcome the scarcity of labeled data; however, a naive application of SSL to ECG data, without considering the spatial-temporal relationships inherent in ECG signals, may yield suboptimal results. In this paper, we introduce ST-MEM (Spatio-Temporal Masked Electrocardiogram Modeling), designed to learn spatio-temporal features by reconstructing masked 12-lead ECG data. ST-MEM outperforms other SSL baseline methods in various experimental settings for arrhythmia classification tasks. Moreover, we demonstrate that ST-MEM is adaptable to various lead combinations. Through quantitative and qualitative analysis, we show a spatio-temporal relationship within ECG data. Our code is available at https://github.com/bakqui/ST-MEM.
Key facts. Cited by 84 papers in the map (data through 7 Oct 2026). Builds on 25 of its 53 references that are in the map. First posted on arXiv 2 Feb 2024.
Builds on
25 of 53 references.
References · 25
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13 more
- 2020CLOCS: Contrastive Learning of Cardiac Signals Across Space, Time, and Patientscited by 170
- 2019Automatic diagnosis of the 12-lead ECG using a deep neural networkcited by 164
- 2020Deep Learning for ECG Analysis: Benchmarks and Insights from PTB-XLcited by 158
- 2020Self-supervised ECG Representation Learning for Emotion Recognitioncited by 99
- 2023What Do Self-Supervised Vision Transformers Learn?cited by 90
- 2021Self-supervised representation learning from 12-lead ECG datacited by 80
- 2022Lead-agnostic Self-supervised Learning for Local and Global Representations of Electrocardiogramcited by 38
- 20213KG: Contrastive Learning of 12-Lead Electrocardiograms using Physiologically-Inspired Augmentationscited by 36
- 2021Intra-Inter Subject Self-supervised Learning for Multivariate Cardiac Signalscited by 35
- 2018ECG arrhythmia classification using a 2-D convolutional neural networkcited by 17
- 2022Analysis of Augmentations for Contrastive ECG Representation Learningcited by 12
- 2023MVKT-ECG: Efficient Single-lead ECG Classification on Multi-Label Arrhythmia by Multi-View Knowledge Transferringcited by 5
- 2020Data Augmentation for Electrocardiogram Classification with Deep Neural Networkcited by 4
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Citing papers per year: 2024: 12; 2025: 28; 2026: 44.
84 papers.
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- 2024ECG-FM: An Open Electrocardiogram Foundation Modelcited by 89
- 2024Zero-Shot ECG Classification with Multimodal Learning and Test-time Clinical Knowledge Enhancementcited by 66
- 2025Reading Your Heart: Learning ECG Words and Sentences via Pre-training ECG Language Modelcited by 36
- 2024MEIT: Multimodal Electrocardiogram Instruction Tuning on Large Language Models for Report Generationcited by 29
- 2024An Electrocardiogram Foundation Model Built on over 10 Million Recordings with External Evaluation across Multiple Domainscited by 27
- 2024Teach Multimodal LLMs to Comprehend Electrocardiographic Imagescited by 25
- 2025LSM-2: Learning from Incomplete Wearable Sensor Datacited by 20
- 2024Learning General Representation of 12-Lead Electrocardiogram with a Joint-Embedding Predictive Architecturecited by 17
- 2024Boosting Masked ECG-Text Auto-Encoders as Discriminative Learnerscited by 16
- 2025From Token to Rhythm: A Multi-Scale Approach for ECG-Language Pretrainingcited by 15
- 2024Self-Supervised Pre-Training with Joint-Embedding Predictive Architecture Boosts ECG Classification Performancecited by 14
- 2024ECG-Byte: A Tokenizer for End-to-End Generative Electrocardiogram Language Modelingcited by 9
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- 2025anyECG-chat: A Generalist ECG-MLLM for Flexible ECG Input and Multi-Task Understandingcited by 9
- 2024ECHOPulse: ECG controlled echocardio-grams video generationcited by 8
- 2025BenchECG and xECG: a benchmark and baseline for ECG foundation modelscited by 8
- 2026ECG-R1: Protocol-Guided and Modality-Agnostic MLLM for Reliable ECG Interpretationcited by 8
- 2026OSF: On Pre-training and Scaling of Sleep Foundation Modelscited by 8
- 2025CLEF: Clinically-Guided Contrastive Learning for Electrocardiogram Foundation Modelscited by 7
- 2025SuPreME: A Supervised Pre-training Framework for Multimodal ECG Representation Learningcited by 6
- 2025Benchmarking ECG FMs: A Reality Check Across Clinical Taskscited by 6
- 2024AnyECG: Foundational Models for Multitask Cardiac Analysis in Real-World Settingscited by 5
- 2025Knowledge-enhanced Multimodal ECG Representation Learning with Arbitrary-Lead Inputscited by 5
- 2025Global and Local Contrastive Learning for Joint Representations from Cardiac MRI and ECGcited by 5
- 2025Self-Alignment Learning to Improve Myocardial Infarction Detection from Single-Lead ECGcited by 4
- 2024Translating Electrocardiograms to Cardiac Magnetic Resonance Imaging Useful for Cardiac Assessment and Disease Screening: A Multi-Center Studycited by 3
- 2025Interpretable Multimodal Zero-Shot ECG Diagnosis via Structured Clinical Knowledge Alignmentcited by 3
- 2026RhythmBERT: A Self-Supervised Language Model Based on Latent Representations of ECG Waveforms for Heart Disease Detectioncited by 3
- 2026CardioState-JEPA: Delay-Aware Cross-Modal Learning of a Shared Cardiac Representationcited by 3
- 2025FOCAL: Fine-Grained Optimal-Transport-Driven Contrastive Alignment of Language and ECGs with Waveform Enhancementcited by 2
- 2025Signal, Image, or Symbolic: Exploring the Best Input Representation for Electrocardiogram-Language Models Through a Unified Frameworkcited by 2
- 2025SemiSegECG: A Multi-Dataset Benchmark for Semi-Supervised Semantic Segmentation in ECG Delineationcited by 2
- 2025A Unified AI Approach for Continuous Monitoring of Human Health and Diseases from Intensive Care Unit to Home with Physiological Foundation Models (UNIPHY+)cited by 2
- 2025Fusion of ECG Foundation Model Embeddings to Improve Early Detection of Acute Coronary Syndromescited by 1
- 2025Enhancing Contrastive Learning-based Electrocardiogram Pretrained Model with Patient Memory Queuecited by 1
- 2025ECG-Soup: Harnessing Multi-Layer Synergy for ECG Foundation Modelscited by 1
- 2025Domain Knowledge is Power: Leveraging Physiological Priors for Self Supervised Representation Learning in Electrocardiographycited by 1
- 2025Tracing the Heart's Pathways: ECG Representation Learning from a Cardiac Conduction Perspectivecited by 1
- 2026Foundation Model for Cardiac Time Series via Masked Latent Attentioncited by 1
- 2026LVCG: Learning ECG Representations in the Latent Vectorcardiogram Spacecited by 1
- 2026Hierarchical Self-Supervised Representation Learning Framework for Multivariate Time Series Grounded in ECG Analysiscited by 1
- 2025CuPID: Leveraging Masked Single-Lead ECG Modelling for Enhancing the Representationscited by 0
- 2025Parallel-Learning of Invariant and Tempo-variant Attributes of Single-Lead Cardiac Signals: PLITAcited by 0
- 2025Multimodal Latent Fusion of ECG Leads for Early Assessment of Pulmonary Hypertensioncited by 0
- 2025Masked Autoencoders that Feel the Heart: Unveiling Simplicity Bias for ECG Analysescited by 0
- 2025A Language-Signal-Vision Multimodal Framework for Multitask Cardiac Analysiscited by 0
- 2025A Masked Representation Learning to Model Cardiac Functions Using Multiple Physiological Signalscited by 0
- 2025Bridging Performance Gaps for ECG Foundation Models: A Post-Training Strategycited by 0
- 2026BEAT-Net: Injecting Biomimetic Spatio-Temporal Priors for Interpretable ECG Diagnosiscited by 0
- 2026ELF: A Family of Encoder-Free ECG-Language Modelscited by 0
- 2026Position: Evaluation of ECG Representations Must Be Fixedcited by 0
50 most cited of 84 All 84 (JSON)
- 2026TRACE: Expert-Aligned ECG Representation Learning with Rigorous Benchmarking and Real-World Validation in Acute Cardiac Care28 Sep 2026
- 2026BeatGraph: Self-Supervised Heartbeat Graphs for Infant ECG Representations from the Home Environment25 Sep 2026
- 2026When Does Unsupervised Learning Succeed or Fail? A PoS Perspective on Reconstruction-Based Anomaly Detection23 Sep 2026
- 2026TRACE: Tractable Routing Autoencoder for Clinical ECG20 Sep 2026
- 2026Reading the Whole Heart: Latent-Attention Masked Autoencoders for Multimodal Cardiac Representation Learning10 Sep 2026
- 2026Beat-Synchronous Tokenization for ECG Transformers31 Aug 2026
- 2026Graph-Based Pseudo-multimodal Contrastive Learning for 12-Lead ECG Representations27 Aug 2026
- 2026Attributing Preprocessing Invariance in Spectral Foundation Models14 Aug 2026
- 2026CardioState-JEPA: Delay-Aware Cross-Modal Learning of a Shared Cardiac Representation13 Aug 2026
- 2026The Impact of Temporal Context Length and Encoding Strategies on Self-Supervised ECG Representation Learning13 Aug 2026
- 2026Diagnosing as Cardiologists Do: ECG Agents with Doctor-Grounded Priors for Clinical Reasoning Across Diseases and Populations10 Aug 2026
- 2026ECG-LENS: Lead-Aware Clinical Context Enriched ECG Report Generation and Evaluation6 Aug 2026
38 more
- 2026LAEF: A Lead-Agnostic ECG Foundation Model Towards Point-of-Care Diagnostics4 Aug 2026
- 2026FOUND-AF: Benchmarking ECG Foundation Models for Atrial Fibrillation Detection4 Aug 2026
- 2026PhysioBench: A Unified Benchmark for Physiological Signal Question Answering29 Jul 2026
- 2026ECG-InterpBench: Benchmarking the Interpretability of ECG Foundation Models with Matched-Scale Sparse Autoencoders29 Jul 2026
- 2026CADENCE: A Cardiac Atom Dictionary for Interpretable Neural Concept Extraction from ECG Foundation Models28 Jul 2026
- 2026EchoBridge: Long-Tail-Aware ECG-Echocardiography Text Alignment for Echocardiography-Derived Cardiac Findings27 Jul 2026
- 2026Failures Reveal What Metrics Miss: An Evidence-Driven Agent for Recursive Refinement of ECG Classifiers27 Jul 2026
- 2026Knowledge-Guided Cross-Modal Fusion for Adult-to-Pediatric ECG Transfer via Label-Conditioned Contrastive Alignment17 Jul 2026
- 2026NeuroECG: ECGFounder-Based Deep ECG Representation for EEG-Free Neurological Prognostication After Cardiac Arrest13 Jul 2026
- 2026Do ECG Foundation Models Transfer to Rare Cardiac Diseases? Evidence from Brugada Syndrome Detection3 Jul 2026
- 2026Hierarchical Self-Supervised Representation Learning Framework for Multivariate Time Series Grounded in ECG Analysis1 Jul 2026
- 2026SPOTR: Spatio-temporal Pooling One-Token Reconstruction for Universal Physiological Signal Self-supervised Learning20 Jun 2026
- 2026Cohort-Anchored Foundation Models for Electronic Health Records: From Risk Scores to Auditable Peer Cohorts20 Jun 2026
- 2026LVCG: Learning ECG Representations in the Latent Vectorcardiogram Space29 May 2026
- 2026Information-theoretic Multimodal Representation Learning for Electrocardiogram Signals26 May 2026
- 2026Prototype-Guided Classification Sub-Task Decoupling Framework: Enhancing Generalization and Interpretability for Multivariate Time Series21 May 2026
- 2026Bidirectional Fusion Guided by Cardiac Patterns for Semi-Supervised ECG Segmentation15 May 2026
- 2026VCR: Learning Valid Contextual Representation for Incomplete Wearable Signals13 May 2026
- 2026ECG-NAT: A Self-supervised Neighborhood Attention Transformer for Multi-lead Electrocardiogram Classification13 May 2026
- 2026Label-Conditioned Cross-Modal Fusion for Adult-to-Pediatric ECG Transfer via Curriculum-Gated Contrastive Alignment1 May 2026
- 2026CoRe-ECG: Advancing Self-Supervised Representation Learning for 12-Lead ECG via Contrastive and Reconstructive Synergy13 Apr 2026
- 2026Learning ECG Image Representations via Dual Physiological-Aware Alignments2 Apr 2026
- 2026Foundation Model for Cardiac Time Series via Masked Latent Attention27 Mar 2026
- 2026Detecting Structural Heart Disease from Electrocardiograms via a Generalized Additive Model of Interpretable Foundation-Model Predictors3 Mar 2026
- 2026OSF: On Pre-training and Scaling of Sleep Foundation Models27 Feb 2026
- 2026RhythmBERT: A Self-Supervised Language Model Based on Latent Representations of ECG Waveforms for Heart Disease Detection26 Feb 2026
- 2026Chain of Flow: ECG-Conditioned 4D Cardiac Cine Generation from Patient-Specific Anatomical Anchor26 Feb 2026
- 2026CG-DMER: Hybrid Contrastive-Generative Framework for Disentangled Multimodal ECG Representation Learning24 Feb 2026
- 2026Position: Evaluation of ECG Representations Must Be Fixed19 Feb 2026
- 2026ECG-R1: Protocol-Guided and Modality-Agnostic MLLM for Reliable ECG Interpretation4 Feb 2026
- 2026BEAT-Net: Injecting Biomimetic Spatio-Temporal Priors for Interpretable ECG Diagnosis12 Jan 2026
- 2026ELF: A Family of Encoder-Free ECG-Language Models5 Jan 2026
- 2025Tracing the Heart's Pathways: ECG Representation Learning from a Cardiac Conduction Perspective30 Dec 2025
- 2025CLEF: Clinically-Guided Contrastive Learning for Electrocardiogram Foundation Models1 Dec 2025
- 2025Interpretable Multimodal Zero-Shot ECG Diagnosis via Structured Clinical Knowledge Alignment24 Oct 2025
- 2025Benchmarking ECG FMs: A Reality Check Across Clinical Tasks29 Sep 2025
- 2025Self-Alignment Learning to Improve Myocardial Infarction Detection from Single-Lead ECG23 Sep 2025
- 2025A Unified AI Approach for Continuous Monitoring of Human Health and Diseases from Intensive Care Unit to Home with Physiological Foundation Models (UNIPHY+)19 Sep 2025
50 newest of 84 All 84 (JSON)
- 2024ECG-FM: An Open Electrocardiogram Foundation Modelcited by 89
- 2024Zero-Shot ECG Classification with Multimodal Learning and Test-time Clinical Knowledge Enhancementcited by 66
- 2025Reading Your Heart: Learning ECG Words and Sentences via Pre-training ECG Language Modelcited by 36
- 2024MEIT: Multimodal Electrocardiogram Instruction Tuning on Large Language Models for Report Generationcited by 29
- 2024An Electrocardiogram Foundation Model Built on over 10 Million Recordings with External Evaluation across Multiple Domainscited by 27
- 2024Teach Multimodal LLMs to Comprehend Electrocardiographic Imagescited by 25
- 2025LSM-2: Learning from Incomplete Wearable Sensor Datacited by 20
- 2024Learning General Representation of 12-Lead Electrocardiogram with a Joint-Embedding Predictive Architecturecited by 17
- 2024Boosting Masked ECG-Text Auto-Encoders as Discriminative Learnerscited by 16
- 2025From Token to Rhythm: A Multi-Scale Approach for ECG-Language Pretrainingcited by 15
- 2024Self-Supervised Pre-Training with Joint-Embedding Predictive Architecture Boosts ECG Classification Performancecited by 14
- 2024ECG-Byte: A Tokenizer for End-to-End Generative Electrocardiogram Language Modelingcited by 9
12 most cited of 84 All 84 (JSON)
- 2026TRACE: Expert-Aligned ECG Representation Learning with Rigorous Benchmarking and Real-World Validation in Acute Cardiac Care28 Sep 2026
- 2026BeatGraph: Self-Supervised Heartbeat Graphs for Infant ECG Representations from the Home Environment25 Sep 2026
- 2026When Does Unsupervised Learning Succeed or Fail? A PoS Perspective on Reconstruction-Based Anomaly Detection23 Sep 2026
- 2026TRACE: Tractable Routing Autoencoder for Clinical ECG20 Sep 2026
- 2026Reading the Whole Heart: Latent-Attention Masked Autoencoders for Multimodal Cardiac Representation Learning10 Sep 2026
- 2026Beat-Synchronous Tokenization for ECG Transformers31 Aug 2026
- 2026Graph-Based Pseudo-multimodal Contrastive Learning for 12-Lead ECG Representations27 Aug 2026
- 2026Attributing Preprocessing Invariance in Spectral Foundation Models14 Aug 2026
- 2026CardioState-JEPA: Delay-Aware Cross-Modal Learning of a Shared Cardiac Representation13 Aug 2026
- 2026The Impact of Temporal Context Length and Encoding Strategies on Self-Supervised ECG Representation Learning13 Aug 2026
- 2026Diagnosing as Cardiologists Do: ECG Agents with Doctor-Grounded Priors for Clinical Reasoning Across Diseases and Populations10 Aug 2026
- 2026ECG-LENS: Lead-Aware Clinical Context Enriched ECG Report Generation and Evaluation6 Aug 2026
12 newest of 84 All 84 (JSON)