mlsanityData to 7 Oct 2026

Knowledge-enhanced Multimodal ECG Representation Learning with Arbitrary-Lead Inputs

arXiv 2502.17900 ↗First posted 25 Feb 2025cs.LG cs.AIcited by 5

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Abstract (arXiv)

Recent advances in multimodal ECG representation learning center on aligning ECG signals with paired free-text reports. However, suboptimal alignment persists due to the complexity of medical language and the reliance on a full 12-lead setup, which is often unavailable in under-resourced settings. To tackle these issues, we propose **K-MERL**, a knowledge-enhanced multimodal ECG representation learning framework. **K-MERL** leverages large language models to extract structured knowledge from free-text reports and employs a lead-aware ECG encoder with dynamic lead masking to accommodate arbitrary lead inputs. Evaluations on six external ECG datasets show that **K-MERL** achieves state-of-the-art performance in zero-shot classification and linear probing tasks, while delivering an average **16%** AUC improvement over existing methods in partial-lead zero-shot classification.

Key facts. Cited by 5 papers in the map (data through 7 Oct 2026). Builds on 25 of its 66 references that are in the map. First posted on arXiv 25 Feb 2025.

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25 of 66 references.

References · 25

  1. 2020A Simple Framework for Contrastive Learning of Visual Representationscited by 11,979
  2. 2020Bootstrap your own latent: A new approach to self-supervised Learningcited by 4,712
  3. 2020Exploring Simple Siamese Representation Learningcited by 2,853
  4. 2021Barlow Twins: Self-Supervised Learning via Redundancy Reductioncited by 1,818
  5. 2021An Empirical Study of Training Self-Supervised Vision Transformerscited by 1,610
  6. 2019Publicly Available Clinical BERT Embeddingscited by 995
  7. 2021Time-Series Representation Learning via Temporal and Contextual Contrastingcited by 342
  8. 2023MedCPT: Contrastive Pre-trained Transformers with Large-scale PubMed Search Logs for Zero-shot Biomedical Information Retrievalcited by 182
  9. 2020CLOCS: Contrastive Learning of Cardiac Signals Across Space, Time, and Patientscited by 170
  10. 2019Automatic diagnosis of the 12-lead ECG using a deep neural networkcited by 164
  11. 2023Knowledge-enhanced Visual-Language Pre-training on Chest Radiology Imagescited by 128
  12. 2024ECG-FM: An Open Electrocardiogram Foundation Modelcited by 89
13 more
  1. 2024Guiding Masked Representation Learning to Capture Spatio-Temporal Relationship of Electrocardiogramcited by 84
  2. 2019Attention Based Glaucoma Detection: A Large-scale Database and CNN Modelcited by 75
  3. 2024Zero-Shot ECG Classification with Multimodal Learning and Test-time Clinical Knowledge Enhancementcited by 66
  4. 2023Med-UniC: Unifying Cross-Lingual Medical Vision-Language Pre-Training by Diminishing Biascited by 57
  5. 2022Self-Supervised Time Series Representation Learning via Cross Reconstruction Transformercited by 47
  6. 2022Lead-agnostic Self-supervised Learning for Local and Global Representations of Electrocardiogramcited by 38
  7. 2024ECG-Chat: A Large ECG-Language Model for Cardiac Disease Diagnosiscited by 37
  8. 2025Reading Your Heart: Learning ECG Words and Sentences via Pre-training ECG Language Modelcited by 36
  9. 2023ETP: Learning Transferable ECG Representations via ECG-Text Pre-trainingcited by 28
  10. 2024Decomposing Disease Descriptions for Enhanced Pathology Detection: A Multi-Aspect Vision-Language Pre-training Frameworkcited by 27
  11. 2024ECG Semantic Integrator (ESI): A Foundation ECG Model Pretrained with LLM-Enhanced Cardiological Textcited by 25
  12. 2023G2D: From Global to Dense Radiography Representation Learning via Vision-Language Pre-trainingcited by 12
  13. 2023Spectral Cross-Domain Neural Network with Soft-adaptive Threshold Spectral Enhancementcited by 4

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Citing papers per year: 2025: 1; 2026: 4.

5 papers.