mlsanityData to 14 Oct 2026

Graph-Based Pseudo-multimodal Contrastive Learning for 12-Lead ECG Representations

arXiv 2608.26964 ↗First posted 27 Aug 2026cs.LGcited by 0

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Abstract (arXiv)

12-lead electrocardiogram (ECG) is a standard, non-invasive examination widely used for diagnosing coronary artery disease, where clinical interpretation relies on comparing waveform patterns across multiple leads. However, most existing ECG analysis methods focus on single-lead signals or treat each lead independently, and typically process ECG signals as one-dimensional time-series data using CNNs or RNNs. While effective in modeling local waveform changes, such approaches have difficulty capturing inter-lead dependency and global waveform patterns essential for clinical diagnosis. To address this limitation, we propose a graph-based pseudo-multimodal contrastive learning framework called Graph-CMMC. ECG waveforms are transformed into Gramian Angular Difference Field (GADF) images to construct complementary representations of the same cardiac activity, enabling a pseudo-multimodal learning setting. Using all 12 leads, Graph-CMMC aligns waveform and GADF representations in a self-supervised manner, while a graph-based relational module is employed to model inter-lead dependency and enforce structural consistency across leads during contrastive learning. Experimental results on a multi-label coronary artery occlusion classification task demonstrate that the proposed framework achieves competitive performance compared to supervised learning methods. These results further suggest the effectiveness of using GADF as a complementary representation and incorporating explicit graph-based modeling of inter-lead dependency for learning robust 12-lead ECG representations.

Key facts. No citing papers in the map yet (data through 14 Oct 2026). Builds on 7 of its 11 references that are in the map. First posted on arXiv 27 Aug 2026.

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References · 7

  1. 2020A Simple Framework for Contrastive Learning of Visual Representationscited by 12,049
  2. 2017Gate-Variants of Gated Recurrent Unit (GRU) Neural Networkscited by 242
  3. 2020CLOCS: Contrastive Learning of Cardiac Signals Across Space, Time, and Patientscited by 171
  4. 2020Deep Learning for ECG Analysis: Benchmarks and Insights from PTB-XLcited by 158
  5. 2015Imaging Time-Series to Improve Classification and Imputationcited by 85
  6. 2024Guiding Masked Representation Learning to Capture Spatio-Temporal Relationship of Electrocardiogramcited by 84
  7. 2023Inferior Myocardial Infarction Detection from lead II of ECG: A Gramian Angular Field-based 2D-CNN Approachcited by 2

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