MVKT-ECG: Efficient Single-lead ECG Classification on Multi-Label Arrhythmia by Multi-View Knowledge Transferring

The widespread emergence of smart devices for ECG has sparked demand for intelligent single-lead ECG-based diagnostic systems. However, it is challenging to develop a single-lead-based ECG interpretation model for multiple diseases diagnosis due to the lack of some key disease information. In this work, we propose inter-lead Multi-View Knowledge Transferring of ECG (MVKT-ECG) to boost single-lead ECG's ability for multi-label disease diagnosis. This training strategy can transfer superior disease knowledge from multiple different views of ECG (e.g. 12-lead ECG) to single-lead-based ECG interpretation model to mine details in single-lead ECG signals that are easily overlooked by neural networks. MVKT-ECG allows this lead variety as a supervision signal within a teacher-student paradigm, where the teacher observes multi-lead ECG educates a student who observes only single-lead ECG. Since the mutual disease information between the single-lead ECG and muli-lead ECG plays a key role in knowledge transferring, we present a new disease-aware Contrastive Lead-information Transferring(CLT) to improve the mutual disease information between the single-lead ECG and muli-lead ECG. Moreover, We modify traditional Knowledge Distillation to multi-label disease Knowledge Distillation (MKD) to make it applicable for multi-label disease diagnosis. The comprehensive experiments verify that MVKT-ECG has an excellent performance in improving the diagnostic effect of single-lead ECG.