A Closer Look at AUROC and AUPRC under Class Imbalance
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Abstract (arXiv)
In machine learning (ML), a widespread claim is that the area under the precision-recall curve (AUPRC) is a superior metric for model comparison to the area under the receiver operating characteristic (AUROC) for tasks with class imbalance. This paper refutes this notion on two fronts. First, we theoretically characterize the behavior of AUROC and AUPRC in the presence of model mistakes, establishing clearly that AUPRC is not generally superior in cases of class imbalance. We further show that AUPRC can be a harmful metric as it can unduly favor model improvements in subpopulations with more frequent positive labels, heightening algorithmic disparities. Next, we empirically support our theory using experiments on both semi-synthetic and real-world fairness datasets. Prompted by these insights, we conduct a review of over 1.5 million scientific papers to understand the origin of this invalid claim, finding that it is often made without citation, misattributed to papers that do not argue this point, and aggressively over-generalized from source arguments. Our findings represent a dual contribution: a significant technical advancement in understanding the relationship between AUROC and AUPRC and a stark warning about unchecked assumptions in the ML community.
Key facts. Cited by 56 papers in the map (data through 7 Oct 2026). Builds on 101 of its 169 references that are in the map. First posted on arXiv 11 Jan 2024.
Builds on
101 of 169 references.
References · 101
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50 most cited of 101 All 101 (JSON)
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Citing papers per year: 2024: 10; 2025: 23; 2026: 23.
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- 2024Developing ChemDFM as a large language foundation model for chemistrycited by 51
- 2024REALM: RAG-Driven Enhancement of Multimodal Electronic Health Records Analysis via Large Language Modelscited by 21
- 2024Enhancing clinical decision support with physiological waveforms -- a multimodal benchmark in emergency carecited by 13
- 2024Training a high-performance retinal foundation model with half-the-data and 400 times less computecited by 9
- 2024TimEHR: Image-based Time Series Generation for Electronic Health Recordscited by 8
- 2025A Collection of Innovations in Medical AI for patient records in 2024cited by 7
- 2025Benchmarking ECG FMs: A Reality Check Across Clinical Taskscited by 6
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- 2024Abnormality Prediction and Forecasting of Laboratory Values from Electrocardiogram Signals Using Multimodal Deep Learningcited by 5
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- 2026When Identical Rows Disagree: From Benchmark Identifiability to Replication-Robust Anomaly Detection27 Aug 2026
- 2026Unsupervised Anomaly Detection Using Flow Matching on Tabular Data20 Aug 2026
- 2026Auditing Frame-Level AUC in Weakly Supervised Video Anomaly Detection: Granularity, Resolution, and Scene Bias12 Aug 2026
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- 2026Enhancing Extubation Failure Prediction with LLM-Derived Features from Respiratory Therapy Clinical Notes17 Jun 2026
- 2026A multi-agent system for spine MRI report generation from multi-sequence imaging8 Jun 2026
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