mlsanityData to 7 Oct 2026

Foundations and Trends in Multimodal Machine Learning: Principles, Challenges, and Open Questions

arXiv 2209.03430 ↗First posted 7 Sep 2022cs.LG cs.AI cs.CLcited by 116

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Abstract (arXiv)

Multimodal machine learning is a vibrant multi-disciplinary research field that aims to design computer agents with intelligent capabilities such as understanding, reasoning, and learning through integrating multiple communicative modalities, including linguistic, acoustic, visual, tactile, and physiological messages. With the recent interest in video understanding, embodied autonomous agents, text-to-image generation, and multisensor fusion in application domains such as healthcare and robotics, multimodal machine learning has brought unique computational and theoretical challenges to the machine learning community given the heterogeneity of data sources and the interconnections often found between modalities. However, the breadth of progress in multimodal research has made it difficult to identify the common themes and open questions in the field. By synthesizing a broad range of application domains and theoretical frameworks from both historical and recent perspectives, this paper is designed to provide an overview of the computational and theoretical foundations of multimodal machine learning. We start by defining three key principles of modality heterogeneity, connections, and interactions that have driven subsequent innovations, and propose a taxonomy of six core technical challenges: representation, alignment, reasoning, generation, transference, and quantification covering historical and recent trends. Recent technical achievements will be presented through the lens of this taxonomy, allowing researchers to understand the similarities and differences across new approaches. We end by motivating several open problems for future research as identified by our taxonomy.

Key facts. Cited by 116 papers in the map (data through 7 Oct 2026). Builds on 225 of its 435 references that are in the map. First posted on arXiv 7 Sep 2022.

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225 of 435 references.

References · 225

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50 most cited of 225 All 225 (JSON)

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Cited by year (2026 to 7 Oct)

Citing papers per year: 2023: 5; 2024: 23; 2025: 48; 2026: 40.

116 papers.

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  1. 2024Multimodal Alignment and Fusion: A Surveycited by 73
  2. 2025A Survey on Large Language Models for Mathematical Reasoningcited by 52
  3. 2024The Curse of Multi-Modalities: Evaluating Hallucinations of Large Multimodal Models across Language, Visual, and Audiocited by 48
  4. 2025QoQ-Med: Building Multimodal Clinical Foundation Models with Domain-Aware GRPO Trainingcited by 38
  5. 2025Understanding the Emergence of Multimodal Representation Alignmentcited by 28
  6. 2025Multi-modal Time Series Analysis: A Tutorial and Surveycited by 24
  7. 2024Towards Urban General Intelligence: A Review and Outlook of Urban Foundation Modelscited by 23
  8. 2025DecAlign: Hierarchical Cross-Modal Alignment for Decoupled Multimodal Representation Learningcited by 23
  9. 2024HEMM: Holistic Evaluation of Multimodal Foundation Modelscited by 21
  10. 2023Multimodal Learning Without Labeled Multimodal Data: Guarantees and Applicationscited by 20
  11. 2023Understanding Unimodal Bias in Multimodal Deep Linear Networkscited by 18
  12. 2024Survey of Large Multimodal Model Datasets, Application Categories and Taxonomycited by 17
38 more
  1. 2025DynCIM: Dynamic Curriculum for Imbalanced Multimodal Learningcited by 16
  2. 2024IoT-LM: Large Multisensory Language Models for the Internet of Thingscited by 14
  3. 2024MM-Path: Multi-modal, Multi-granularity Path Representation Learning -- Extended Versioncited by 14
  4. 2024Cohort-Individual Cooperative Learning for Multimodal Cancer Survival Analysiscited by 13
  5. 2024Rethinking the Power of Timestamps for Robust Time Series Forecasting: A Global-Local Fusion Perspectivecited by 13
  6. 2024Balancing Multimodal Training Through Game-Theoretic Regularizationcited by 13
  7. 2025CLIMB: Data Foundations for Large Scale Multimodal Clinical Foundation Modelscited by 13
  8. 2024Segment Anything with Multiple Modalitiescited by 12
  9. 2024MedualTime: A Dual-Adapter Language Model for Medical Time Series-Text Multimodal Learningcited by 11
  10. 2024Progressive Compositionality in Text-to-Image Generative Modelscited by 11
  11. 2025OPENTOUCH: Bringing Full-Hand Touch to Real-World Interactioncited by 11
  12. 2024Towards Modality Generalization: A Benchmark and Prospective Analysiscited by 10
  13. 2024Beyond DAGs: A Latent Partial Causal Model for Multimodal Learningcited by 9
  14. 2024Textualized and Feature-based Models for Compound Multimodal Emotion Recognition in the Wildcited by 9
  15. 2025MimeQA: Towards Socially-Intelligent Nonverbal Foundation Modelscited by 9
  16. 2025Interactive Sketchpad: A Multimodal Tutoring System for Collaborative, Visual Problem-Solvingcited by 9
  17. 2025SmellNet: A Large-scale Dataset for Real-world Smell Recognitioncited by 9
  18. 2023Dissecting Multimodality in VideoQA Transformer Models by Impairing Modality Fusioncited by 8
  19. 2025Modality Interactive Mixture-of-Experts for Fake News Detectioncited by 8
  20. 2025REDELEX: A Framework for Relational Deep Learning Explorationcited by 8
  21. 2025PuzzleWorld: A Benchmark for Multimodal, Open-Ended Reasoning in Puzzlehuntscited by 7
  22. 2025Deep Learning in Concealed Dense Predictioncited by 6
  23. 2025POET: Supporting Prompting Creativity and Personalization with Automated Expansion of Text-to-Image Generationcited by 6
  24. 2023Advancing Drug Discovery with Enhanced Chemical Understanding via Asymmetric Contrastive Multimodal Learningcited by 5
  25. 2025Reducing Aleatoric and Epistemic Uncertainty through Multi-modal Data Acquisitioncited by 5
  26. 2025Human Behavior Atlas: Benchmarking Unified Psychological and Social Behavior Understandingcited by 5
  27. 2024Global Contrastive Training for Multimodal Electronic Health Records with Language Supervisioncited by 4
  28. 2024End-to-end Semantic-centric Video-based Multimodal Affective Computingcited by 4
  29. 2024Anchors Aweigh! Sail for Optimal Unified Multi-Modal Representationscited by 4
  30. 2025Massively Multimodal Foundation Models: A Framework for Capturing Interactions with Specialized Mixture-of-Expertscited by 4
  31. 2025Partial Information Decomposition via Normalizing Flows in Latent Gaussian Distributionscited by 4
  32. 2026CyIN: Cyclic Informative Latent Space for Bridging Complete and Incomplete Multimodal Learningcited by 4
  33. 2025Towards Multimodal Active Learning: Efficient Learning with Limited Paired Datacited by 3
  34. 2026TopoCL: Topological Contrastive Learning for Medical Imagingcited by 3
  35. 2024Keypoint-Integrated Instruction-Following Data Generation for Enhanced Human Pose and Action Understanding in Multimodal Modelscited by 2
  36. 2025Towards deployment-centric multimodal AI beyond vision and languagecited by 2
  37. 2025MINT: Multimodal Instruction Tuning with Multimodal Interaction Groupingcited by 2
  38. 2025Federated Learning from Molecules to Processes: A Perspectivecited by 2

50 most cited of 116 All 116 (JSON)