AFTer-UNet: Axial Fusion Transformer UNet for Medical Image Segmentation
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Abstract (arXiv)
Recent advances in transformer-based models have drawn attention to exploring these techniques in medical image segmentation, especially in conjunction with the U-Net model (or its variants), which has shown great success in medical image segmentation, under both 2D and 3D settings. Current 2D based methods either directly replace convolutional layers with pure transformers or consider a transformer as an additional intermediate encoder between the encoder and decoder of U-Net. However, these approaches only consider the attention encoding within one single slice and do not utilize the axial-axis information naturally provided by a 3D volume. In the 3D setting, convolution on volumetric data and transformers both consume large GPU memory. One has to either downsample the image or use cropped local patches to reduce GPU memory usage, which limits its performance. In this paper, we propose Axial Fusion Transformer UNet (AFTer-UNet), which takes both advantages of convolutional layers' capability of extracting detailed features and transformers' strength on long sequence modeling. It considers both intra-slice and inter-slice long-range cues to guide the segmentation. Meanwhile, it has fewer parameters and takes less GPU memory to train than the previous transformer-based models. Extensive experiments on three multi-organ segmentation datasets demonstrate that our method outperforms current state-of-the-art methods.
Key facts. Cited by 48 papers in the map (data through 7 Oct 2026). Builds on 41 of its 56 references that are in the map. First posted on arXiv 20 Oct 2021.
Builds on
41 of 56 references.
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Citing papers per year: 2022: 18; 2023: 13; 2024: 10; 2025: 5; 2026: 2.
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- 2024Weak-Mamba-UNet: Visual Mamba Makes CNN and ViT Work Better for Scribble-based Medical Image Segmentation16 Feb 2024
- 2024MOSformer: Momentum encoder-based inter-slice fusion transformer for medical image segmentation22 Jan 2024
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- 2023A Recent Survey of Vision Transformers for Medical Image Segmentation1 Dec 2023
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- 2023Clean Label Disentangling for Medical Image Segmentation with Noisy Labels28 Nov 2023
- 2023Improved TokenPose with Sparsity16 Nov 2023
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- 2023Med-DANet V2: A Flexible Dynamic Architecture for Efficient Medical Volumetric Segmentation28 Oct 2023
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- 2023Distilling Token-Pruned Pose Transformer for 2D Human Pose Estimation12 Apr 2023
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- 2022Diffeomorphic Image Registration with Neural Velocity Field25 Feb 2022
- 2022Transformers in Medical Image Analysis: A Review24 Feb 2022
- 2022Transformers in Medical Imaging: A Survey24 Jan 2022
- 2022Advancing 3D Medical Image Analysis with Variable Dimension Transform based Supervised 3D Pre-training5 Jan 2022
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- 2022Medical Image Segmentation Review: The success of U-Netcited by 190
- 2022STAR-Transformer: A Spatio-temporal Cross Attention Transformer for Human Action Recognitioncited by 43
- 2022Transformers in Medical Image Analysis: A Reviewcited by 41
- 2022Topology-Preserving Shape Reconstruction and Registration via Neural Diffeomorphic Flowcited by 38
- 2023MedGen3D: A Deep Generative Framework for Paired 3D Image and Mask Generationcited by 34
- 2022Transforming medical imaging with Transformers? A comparative review of key properties, current progresses, and future perspectivescited by 32
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- 2023CVTHead: One-shot Controllable Head Avatar with Vertex-feature Transformercited by 24
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- 2026Volumetrically Consistent Implicit Atlas Learning via Neural Diffeomorphic Flow for Placenta MRI17 Mar 2026
- 2026Combining Microscopy Data and Metadata for Reconstruction of Cellular Traction Forces Using a Hybrid Vision Transformer-U-Net11 Mar 2026
- 2025Focal Modulation and Bidirectional Feature Fusion Network for Medical Image Segmentation23 Oct 2025
- 2025Spatiotemporal wall pressure forecast of a rectangular cylinder with physics-aware DeepU-Fourier neural network5 Aug 2025
- 2025Medical Image Segmentation Using Advanced Unet: VMSE-Unet and VM-Unet CBAM+1 Jul 2025
- 2025Rethinking Boundary Detection in Deep Learning-Based Medical Image Segmentation6 May 2025
- 2025MedSegFactory: Text-Guided Generation of Medical Image-Mask Pairs9 Apr 2025
- 2024A Machine Learning Approach for the Efficient Estimation of Ground-Level Air Temperature in Urban Areas5 Nov 2024
- 2024CONSULT: Contrastive Self-Supervised Learning for Few-shot Tumor Detection15 Oct 2024
- 2024TBConvL-Net: A Hybrid Deep Learning Architecture for Robust Medical Image Segmentation5 Sep 2024
- 2024A Refreshed Similarity-based Upsampler for Direct High-Ratio Feature Upsampling2 Jul 2024
- 2024Cross-Slice Attention and Evidential Critical Loss for Uncertainty-Aware Prostate Cancer Detection1 Jul 2024
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