mlsanityData to 7 Oct 2026

AFTer-UNet: Axial Fusion Transformer UNet for Medical Image Segmentation

arXiv 2110.10403 ↗First posted 20 Oct 2021eess.IV cs.CV cs.LGcited by 48

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Abstract (arXiv)

Recent advances in transformer-based models have drawn attention to exploring these techniques in medical image segmentation, especially in conjunction with the U-Net model (or its variants), which has shown great success in medical image segmentation, under both 2D and 3D settings. Current 2D based methods either directly replace convolutional layers with pure transformers or consider a transformer as an additional intermediate encoder between the encoder and decoder of U-Net. However, these approaches only consider the attention encoding within one single slice and do not utilize the axial-axis information naturally provided by a 3D volume. In the 3D setting, convolution on volumetric data and transformers both consume large GPU memory. One has to either downsample the image or use cropped local patches to reduce GPU memory usage, which limits its performance. In this paper, we propose Axial Fusion Transformer UNet (AFTer-UNet), which takes both advantages of convolutional layers' capability of extracting detailed features and transformers' strength on long sequence modeling. It considers both intra-slice and inter-slice long-range cues to guide the segmentation. Meanwhile, it has fewer parameters and takes less GPU memory to train than the previous transformer-based models. Extensive experiments on three multi-organ segmentation datasets demonstrate that our method outperforms current state-of-the-art methods.

Key facts. Cited by 48 papers in the map (data through 7 Oct 2026). Builds on 41 of its 56 references that are in the map. First posted on arXiv 20 Oct 2021.

Builds on

41 of 56 references.

References · 41

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29 more
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Cited by year (2026 to 7 Oct)

Citing papers per year: 2022: 18; 2023: 13; 2024: 10; 2025: 5; 2026: 2.

48 papers.

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  1. 2022Transformers in Medical Imaging: A Surveycited by 245
  2. 2022Medical Image Segmentation Review: The success of U-Netcited by 190
  3. 2022STAR-Transformer: A Spatio-temporal Cross Attention Transformer for Human Action Recognitioncited by 43
  4. 2022Transformers in Medical Image Analysis: A Reviewcited by 41
  5. 2022Topology-Preserving Shape Reconstruction and Registration via Neural Diffeomorphic Flowcited by 38
  6. 2023MedGen3D: A Deep Generative Framework for Paired 3D Image and Mask Generationcited by 34
  7. 2022Transforming medical imaging with Transformers? A comparative review of key properties, current progresses, and future perspectivescited by 32
  8. 2024Weak-Mamba-UNet: Visual Mamba Makes CNN and ViT Work Better for Scribble-based Medical Image Segmentationcited by 29
  9. 2022PPT: token-Pruned Pose Transformer for monocular and multi-view human pose estimationcited by 27
  10. 2023CVTHead: One-shot Controllable Head Avatar with Vertex-feature Transformercited by 24
  11. 2023A Recent Survey of Vision Transformers for Medical Image Segmentationcited by 22
  12. 20223D Vision with Transformers: A Surveycited by 21
36 more
  1. 2023Alternate Diverse Teaching for Semi-supervised Medical Image Segmentationcited by 21
  2. 2022Diffeomorphic Image Registration with Neural Velocity Fieldcited by 20
  3. 2023Transformers in Healthcare: A Surveycited by 17
  4. 2022A survey on attention mechanisms for medical applications: are we moving towards better algorithms?cited by 15
  5. 2025MedSegFactory: Text-Guided Generation of Medical Image-Mask Pairscited by 13
  6. 2023SPPNet: A Single-Point Prompt Network for Nuclei Image Segmentationcited by 12
  7. 2022Identity-Aware Hand Mesh Estimation and Personalization from RGB Imagescited by 11
  8. 2022Recent Progress in Transformer-based Medical Image Analysiscited by 9
  9. 2023Attention Mechanisms in Medical Image Segmentation: A Surveycited by 9
  10. 2024TBConvL-Net: A Hybrid Deep Learning Architecture for Robust Medical Image Segmentationcited by 8
  11. 2022Transformer based Models for Unsupervised Anomaly Segmentation in Brain MR Imagescited by 7
  12. 2023CSAM: A 2.5D Cross-Slice Attention Module for Anisotropic Volumetric Medical Image Segmentationcited by 7
  13. 2024A Refreshed Similarity-based Upsampler for Direct High-Ratio Feature Upsamplingcited by 7
  14. 2022Transformers Meet Visual Learning Understanding: A Comprehensive Reviewcited by 5
  15. 2022Understanding the Tricks of Deep Learning in Medical Image Segmentation: Challenges and Future Directionscited by 5
  16. 2023MCANet: Medical Image Segmentation with Multi-Scale Cross-Axis Attentioncited by 5
  17. 2022Advancing 3D Medical Image Analysis with Variable Dimension Transform based Supervised 3D Pre-trainingcited by 3
  18. 2022ConvTransSeg: A Multi-resolution Convolution-Transformer Network for Medical Image Segmentationcited by 3
  19. 2024AgileFormer: Spatially Agile Transformer UNet for Medical Image Segmentationcited by 3
  20. 2024Are Vision xLSTM Embedded UNet More Reliable in Medical 3D Image Segmentation?cited by 3
  21. 2024MOSformer: Momentum encoder-based inter-slice fusion transformer for medical image segmentationcited by 2
  22. 2024Cross-Slice Attention and Evidential Critical Loss for Uncertainty-Aware Prostate Cancer Detectioncited by 2
  23. 2025Rethinking Boundary Detection in Deep Learning-Based Medical Image Segmentationcited by 2
  24. 2025Spatiotemporal wall pressure forecast of a rectangular cylinder with physics-aware DeepU-Fourier neural networkcited by 2
  25. 2022UNesT: Local Spatial Representation Learning with Hierarchical Transformer for Efficient Medical Segmentationcited by 1
  26. 2023Med-DANet V2: A Flexible Dynamic Architecture for Efficient Medical Volumetric Segmentationcited by 1
  27. 2024A Machine Learning Approach for the Efficient Estimation of Ground-Level Air Temperature in Urban Areascited by 1
  28. 2025Focal Modulation and Bidirectional Feature Fusion Network for Medical Image Segmentationcited by 1
  29. 2023Distilling Token-Pruned Pose Transformer for 2D Human Pose Estimationcited by 0
  30. 2023Improved TokenPose with Sparsitycited by 0
  31. 2023Clean Label Disentangling for Medical Image Segmentation with Noisy Labelscited by 0
  32. 2024Multi-Aperture Fusion of Transformer-Convolutional Network (MFTC-Net) for 3D Medical Image Segmentation and Visualizationcited by 0
  33. 2024CONSULT: Contrastive Self-Supervised Learning for Few-shot Tumor Detectioncited by 0
  34. 2025Medical Image Segmentation Using Advanced Unet: VMSE-Unet and VM-Unet CBAM+cited by 0
  35. 2026Combining Microscopy Data and Metadata for Reconstruction of Cellular Traction Forces Using a Hybrid Vision Transformer-U-Netcited by 0
  36. 2026Volumetrically Consistent Implicit Atlas Learning via Neural Diffeomorphic Flow for Placenta MRIcited by 0