mlsanityData to 7 Oct 2026

UTNet: A Hybrid Transformer Architecture for Medical Image Segmentation

arXiv 2107.00781 ↗First posted 2 Jul 2021cs.CVcited by 116

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Abstract (arXiv)

Transformer architecture has emerged to be successful in a number of natural language processing tasks. However, its applications to medical vision remain largely unexplored. In this study, we present UTNet, a simple yet powerful hybrid Transformer architecture that integrates self-attention into a convolutional neural network for enhancing medical image segmentation. UTNet applies self-attention modules in both encoder and decoder for capturing long-range dependency at different scales with minimal overhead. To this end, we propose an efficient self-attention mechanism along with relative position encoding that reduces the complexity of self-attention operation significantly from O(n2) to approximate O(n). A new self-attention decoder is also proposed to recover fine-grained details from the skipped connections in the encoder. Our approach addresses the dilemma that Transformer requires huge amounts of data to learn vision inductive bias. Our hybrid layer design allows the initialization of Transformer into convolutional networks without a need of pre-training. We have evaluated UTNet on the multi-label, multi-vendor cardiac magnetic resonance imaging cohort. UTNet demonstrates superior segmentation performance and robustness against the state-of-the-art approaches, holding the promise to generalize well on other medical image segmentations.

Key facts. Cited by 116 papers in the map (data through 7 Oct 2026). Builds on 23 of its 31 references that are in the map. First posted on arXiv 2 Jul 2021.

Builds on

23 of 31 references.

References · 23

  1. 2017Attention Is All You Needcited by 59,932
  2. 2015Deep Residual Learning for Image Recognitioncited by 51,809
  3. 2020An Image is Worth 16x16 Words: Transformers for Image Recognition at Scalecited by 29,915
  4. 2015U-Net: Convolutional Networks for Biomedical Image Segmentationcited by 19,604
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11 more
  1. 2018Image Transformercited by 770
  2. 2019Big Transfer (BiT): General Visual Representation Learningcited by 766
  3. 2018CCNet: Criss-Cross Attention for Semantic Segmentationcited by 717
  4. 2019Attention Augmented Convolutional Networkscited by 363
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  6. 2018Attention Gated Networks: Learning to Leverage Salient Regions in Medical Imagescited by 271
  7. 2019Embracing Imperfect Datasets: A Review of Deep Learning Solutions for Medical Image Segmentationcited by 258
  8. 2019Asymmetric Non-local Neural Networks for Semantic Segmentationcited by 196
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Cited by year (2026 to 7 Oct)

Citing papers per year: 2021: 3; 2022: 32; 2023: 28; 2024: 30; 2025: 15; 2026: 8.

116 papers.

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  1. 2022Transformers in Medical Imaging: A Surveycited by 245
  2. 2024nnU-Net Revisited: A Call for Rigorous Validation in 3D Medical Image Segmentationcited by 235
  3. 2021UCTransNet: Rethinking the Skip Connections in U-Net from a Channel-wise Perspective with Transformercited by 197
  4. 2022MALUNet: A Multi-Attention and Light-weight UNet for Skin Lesion Segmentationcited by 59
  5. 2022A Data-scalable Transformer for Medical Image Segmentation: Architecture, Model Efficiency, and Benchmarkcited by 45
  6. 2022Transformers in Medical Image Analysis: A Reviewcited by 41
  7. 2022Transforming medical imaging with Transformers? A comparative review of key properties, current progresses, and future perspectivescited by 32
  8. 2023Training Like a Medical Resident: Context-Prior Learning Toward Universal Medical Image Segmentationcited by 32
  9. 2021iSegFormer: Interactive Segmentation via Transformers with Application to 3D Knee MR Imagescited by 27
  10. 2024Data-Centric Foundation Models in Computational Healthcare: A Surveycited by 27
  11. 2022Surface Vision Transformers: Attention-Based Modelling applied to Cortical Analysiscited by 25
  12. 2023MIS-FM: 3D Medical Image Segmentation using Foundation Models Pretrained on a Large-Scale Unannotated Datasetcited by 25
38 more
  1. 2025MedDINOv3: How to adapt vision foundation models for medical image segmentation?cited by 25
  2. 2024Residual-based Language Models are Free Boosters for Biomedical Imagingcited by 23
  3. 2022Transformer Meets Boundary Value Inverse Problemscited by 22
  4. 2023A Recent Survey of Vision Transformers for Medical Image Segmentationcited by 22
  5. 2025Primus: Enforcing Attention Usage for 3D Medical Image Segmentationcited by 22
  6. 2022Recent Advances in Vision Transformer: A Survey and Outlook of Recent Workcited by 21
  7. 2022TransFusion: Multi-view Divergent Fusion for Medical Image Segmentation with Transformerscited by 21
  8. 2024Semi-Mamba-UNet: Pixel-Level Contrastive and Pixel-Level Cross-Supervised Visual Mamba-based UNet for Semi-Supervised Medical Image Segmentationcited by 20
  9. 2022Multimodal Multi-Head Convolutional Attention with Various Kernel Sizes for Medical Image Super-Resolutioncited by 17
  10. 2022DeepRecon: Joint 2D Cardiac Segmentation and 3D Volume Reconstruction via A Structure-Specific Generative Methodcited by 17
  11. 2023Transformers in Healthcare: A Surveycited by 17
  12. 2024Aligning Human Knowledge with Visual Concepts Towards Explainable Medical Image Classificationcited by 17
  13. 2024MedSAM-U: Uncertainty-Guided Auto Multi-Prompt Adaptation for Reliable MedSAMcited by 17
  14. 2021CyTran: A Cycle-Consistent Transformer with Multi-Level Consistency for Non-Contrast to Contrast CT Translationcited by 15
  15. 2022SepTr: Separable Transformer for Audio Spectrogram Processingcited by 15
  16. 2022CAT-Net: A Cross-Slice Attention Transformer Model for Prostate Zonal Segmentation in MRIcited by 15
  17. 2022BATFormer: Towards Boundary-Aware Lightweight Transformer for Efficient Medical Image Segmentationcited by 14
  18. 2022Region Proposal Rectification Towards Robust Instance Segmentation of Biological Imagescited by 13
  19. 2023M2SNet: Multi-scale in Multi-scale Subtraction Network for Medical Image Segmentationcited by 13
  20. 2023Boundary Difference Over Union Loss For Medical Image Segmentationcited by 13
  21. 2023Adapting Pre-trained Vision Transformers from 2D to 3D through Weight Inflation Improves Medical Image Segmentationcited by 11
  22. 2024Clustering Propagation for Universal Medical Image Segmentationcited by 11
  23. 2022Toward Unpaired Multi-modal Medical Image Segmentation via Learning Structured Semantic Consistencycited by 10
  24. 2022The Lighter The Better: Rethinking Transformers in Medical Image Segmentation Through Adaptive Pruningcited by 9
  25. 2022Recent Progress in Transformer-based Medical Image Analysiscited by 9
  26. 2023Attention Mechanisms in Medical Image Segmentation: A Surveycited by 9
  27. 2023MDViT: Multi-domain Vision Transformer for Small Medical Image Segmentation Datasetscited by 9
  28. 2024TBConvL-Net: A Hybrid Deep Learning Architecture for Robust Medical Image Segmentationcited by 8
  29. 2022Graph Convolutional Networks for Multi-modality Medical Imaging: Methods, Architectures, and Clinical Applicationscited by 7
  30. 2024BRAU-Net++: U-Shaped Hybrid CNN-Transformer Network for Medical Image Segmentationcited by 7
  31. 2024SAM-Mamba: Mamba Guided SAM Architecture for Generalized Zero-Shot Polyp Segmentationcited by 7
  32. 2022Defect Transformer: An Efficient Hybrid Transformer Architecture for Surface Defect Detectioncited by 6
  33. 2023H-DenseFormer: An Efficient Hybrid Densely Connected Transformer for Multimodal Tumor Segmentationcited by 6
  34. 2023Revisiting Computer-Aided Tuberculosis Diagnosiscited by 6
  35. 2024Weight Copy and Low-Rank Adaptation for Few-Shot Distillation of Vision Transformerscited by 6
  36. 2022Retinal Structure Detection in OCTA Image via Voting-based Multi-task Learningcited by 5
  37. 2024SegICL: A Multimodal In-context Learning Framework for Enhanced Segmentation in Medical Imagingcited by 5
  38. 2022A robust and lightweight deep attention multiple instance learning algorithm for predicting genetic alterationscited by 4

50 most cited of 116 All 116 (JSON)