ResUNet++: An Advanced Architecture for Medical Image Segmentation
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Abstract (arXiv)
Accurate computer-aided polyp detection and segmentation during colonoscopy examinations can help endoscopists resect abnormal tissue and thereby decrease chances of polyps growing into cancer. Towards developing a fully automated model for pixel-wise polyp segmentation, we propose ResUNet++, which is an improved ResUNet architecture for colonoscopic image segmentation. Our experimental evaluations show that the suggested architecture produces good segmentation results on publicly available datasets. Furthermore, ResUNet++ significantly outperforms U-Net and ResUNet, two key state-of-the-art deep learning architectures, by achieving high evaluation scores with a dice coefficient of 81.33%, and a mean Intersection over Union (mIoU) of 79.27% for the Kvasir-SEG dataset and a dice coefficient of 79.55%, and a mIoU of 79.62% with CVC-612 dataset.
Key facts. Cited by 211 papers in the map (data through 7 Oct 2026). First posted on arXiv 16 Nov 2019.
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Citing papers per year: 2021: 33; 2022: 27; 2023: 43; 2024: 48; 2025: 38; 2026: 22.
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- 2021TransFuse: Fusing Transformers and CNNs for Medical Image Segmentationcited by 258
- 2021Polyp-PVT: Polyp Segmentation with Pyramid Vision Transformerscited by 159
- 2021DS-TransUNet:Dual Swin Transformer U-Net for Medical Image Segmentationcited by 126
- 2021Shallow Attention Network for Polyp Segmentationcited by 107
- 2023Ambiguous Medical Image Segmentation using Diffusion Modelscited by 92
- 2022Video Polyp Segmentation: A Deep Learning Perspectivecited by 81
- 2021Automatic Polyp Segmentation via Multi-scale Subtraction Networkcited by 77
- 2021Progressively Normalized Self-Attention Network for Video Polyp Segmentationcited by 75
- 2021HarDNet-MSEG: A Simple Encoder-Decoder Polyp Segmentation Neural Network that Achieves over 0.9 Mean Dice and 86 FPScited by 71
- 2021UACANet: Uncertainty Augmented Context Attention for Polyp Segmentationcited by 61
- 2021TransAttUnet: Multi-level Attention-guided U-Net with Transformer for Medical Image Segmentationcited by 60
- 2022TAPE: Task-Agnostic Prior Embedding for Image Restorationcited by 54
38 more
- 2021MSRF-Net: A Multi-Scale Residual Fusion Network for Biomedical Image Segmentationcited by 53
- 2024Vivim: a Video Vision Mamba for Medical Video Segmentationcited by 51
- 2021NeoUNet: Towards accurate colon polyp segmentation and neoplasm detectioncited by 50
- 2023CaraNet: Context Axial Reverse Attention Network for Segmentation of Small Medical Objectscited by 43
- 2021Fast Camouflaged Object Detection via Edge-based Reversible Re-calibration Networkcited by 42
- 2021A Comprehensive Study on Colorectal Polyp Segmentation with ResUNet++, Conditional Random Field and Test-Time Augmentationcited by 41
- 2022DCSAU-Net: A Deeper and More Compact Split-Attention U-Net for Medical Image Segmentationcited by 37
- 2022FCN-Transformer Feature Fusion for Polyp Segmentationcited by 37
- 2021FANet: A Feedback Attention Network for Improved Biomedical Image Segmentationcited by 36
- 2023SAM3D: Segment Anything Model in Volumetric Medical Imagescited by 34
- 2021Enhanced U-Net: A Feature Enhancement Network for Polyp Segmentationcited by 33
- 2022Camouflaged Object Detection via Context-aware Cross-level Fusioncited by 32
- 2023Using DUCK-Net for Polyp Image Segmentationcited by 30
- 2022ColonFormer: An Efficient Transformer based Method for Colon Polyp Segmentationcited by 28
- 2023TransNetR: Transformer-based Residual Network for Polyp Segmentation with Multi-Center Out-of-Distribution Testingcited by 26
- 2024Modality-agnostic Domain Generalizable Medical Image Segmentation by Multi-Frequency in Multi-Scale Attentioncited by 26
- 2021Duplex Contextual Relation Network for Polyp Segmentationcited by 22
- 2022DuAT: Dual-Aggregation Transformer Network for Medical Image Segmentationcited by 22
- 2024UN-SAM: Universal Prompt-Free Segmentation for Generalized Nuclei Imagescited by 22
- 2021Focus U-Net: A novel dual attention-gated CNN for polyp segmentation during colonoscopycited by 20
- 2022TransResU-Net: Transformer based ResU-Net for Real-Time Colonoscopy Polyp Segmentationcited by 19
- 2021NanoNet: Real-Time Polyp Segmentation in Video Capsule Endoscopy and Colonoscopycited by 16
- 2023Shifting More Attention to Breast Lesion Segmentation in Ultrasound Videoscited by 16
- 2023E2ENet: Dynamic Sparse Feature Fusion for Accurate and Efficient 3D Medical Image Segmentationcited by 16
- 2023Dual Cross-Attention for Medical Image Segmentationcited by 15
- 20231M parameters are enough? A lightweight CNN-based model for medical image segmentationcited by 15
- 2023M2SNet: Multi-scale in Multi-scale Subtraction Network for Medical Image Segmentationcited by 13
- 2024Frontiers in Intelligent Colonoscopycited by 13
- 2023A Survey on Deep Learning for Polyp Segmentation: Techniques, Challenges and Future Trendscited by 12
- 2024ProMamba: Prompt-Mamba for polyp segmentationcited by 12
- 2024Decomposition-based Unsupervised Domain Adaptation for Remote Sensing Image Semantic Segmentationcited by 12
- 2021GMSRF-Net: An improved generalizability with global multi-scale residual fusion network for polyp segmentationcited by 11
- 2024BEFUnet: A Hybrid CNN-Transformer Architecture for Precise Medical Image Segmentationcited by 11
- 2022BoxPolyp:Boost Generalized Polyp Segmentation Using Extra Coarse Bounding Box Annotationscited by 10
- 2022Patcher: Patch Transformers with Mixture of Experts for Precise Medical Image Segmentationcited by 9
- 2023ESDMR-Net: A Lightweight Network With Expand-Squeeze and Dual Multiscale Residual Connections for Medical Image Segmentationcited by 9
- 2024Polyp SAM 2: Advancing Zero shot Polyp Segmentation in Colorectal Cancer Detectioncited by 8
- 2025PRS-Med: Position Reasoning Segmentation in Medical Imagingcited by 8
50 most cited of 211 All 211 (JSON)
- 2026LightMIS: Ultra-Lightweight Medical Image Segmentation Without a Stage-Wise Decoder23 Sep 2026
- 2026InstEditSeg: Instruction-Driven Image Editing for Polyp and Skin Lesion Segmentation2 Sep 2026
- 2026Exploring SAM Supervision for Fine-Grained UAV Target Segmentation under Data Scarcity4 Jul 2026
- 2026Does Your ViT Still Need U-Net for Segmentation?30 Jun 2026
- 2026AerialFusionMapNet: Online HD Map Construction with Aerial-Onboard BEV Fusion23 Jun 2026
- 2026Learning a Sampling-Free Variational DNN Plugin from Tiny Training Sets to Refine OOD Segmentation With Uncertainty Estimation14 Jun 2026
- 2026Physics-Constrained Neural Surrogate for Domain Growth Prediction in Systems with Conserved Kinetics9 Jun 2026
- 2026SWARD: Stochastic Window-Attention-Based Relational Distillation for Cross-Architectural Semantic Segmentation31 May 2026
- 20263D Segment Anything Model with Visual Mamba for Diagnosing Placenta Accreta Spectrum30 May 2026
- 2026Learning Ego-Centric BEV Representations from a Perspective-Privileged View: Cross-View Supervision for Online HD Map Construction12 May 2026
- 2026Sharpening Lightweight Models for Generalized Polyp Segmentation: A Boundary Guided Distillation from Foundation Models20 Apr 2026
- 2026WILD-SAM: Phase-Aware Expert Adaptation of SAM for Landslide Detection in Wrapped InSAR Interferograms16 Apr 2026
38 more
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- 2026Dynamics-Informed Deep Learning for Predicting Extreme Events11 Mar 2026
- 2026Weakly Supervised Teacher-Student Framework with Progressive Pseudo-mask Refinement for Gland Segmentation9 Mar 2026
- 2026Unsupervised Semantic Segmentation in Synchrotron Computed Tomography with Self-Correcting Pseudo Labels27 Feb 2026
- 2026From Specialist to Generalist: Unlocking SAM's Learning Potential on Unlabeled Medical Images25 Jan 2026
- 2026Phi-SegNet: Phase-Integrated Supervision for Medical Image Segmentation22 Jan 2026
- 2026SSPFormer: Self-Supervised Pretrained Transformer for MRI Images19 Jan 2026
- 2026POWDR: Pathology-preserving Outpainting with Wavelet Diffusion for 3D MRI14 Jan 2026
- 2026Exploiting DINOv3-Based Self-Supervised Features for Robust Few-Shot Medical Image Segmentation12 Jan 2026
- 2026MetaFormer-driven Encoding Network for Robust Medical Semantic Segmentation1 Jan 2026
- 2025GDKVM: Echocardiography Video Segmentation via Spatiotemporal Key-Value Memory with Gated Delta Rule11 Dec 2025
- 2025Toward Content-based Indexing and Retrieval of Head and Neck CT with Abscess Segmentation1 Dec 2025
- 2025Adversarial Multi-Task Learning for Liver Tumor Segmentation, Dynamic Enhancement Regression, and Classification25 Nov 2025
- 2025HSMix: Hard and Soft Mixing Data Augmentation for Medical Image Segmentation18 Nov 2025
- 2025CephRes-MHNet: A Multi-Head Residual Network for Accurate and Robust Cephalometric Landmark Detection13 Nov 2025
- 2025CLFSeg: A Fuzzy-Logic based Solution for Boundary Clarity and Uncertainty Reduction in Medical Image Segmentation28 Oct 2025
- 2025PVTAdpNet: Polyp Segmentation using Pyramid vision transformer with a novel Adapter block28 Sep 2025
- 2025Improved Segmentation of Polyps and Visual Explainability Analysis17 Sep 2025
- 2025DyGLNet: Hybrid Global-Local Feature Fusion with Dynamic Upsampling for Medical Image Segmentation16 Sep 2025
- 2025Deep Self-knowledge Distillation: A hierarchical supervised learning for coronary artery segmentation3 Sep 2025
- 2025MSA2-Net: Utilizing Self-Adaptive Convolution Module to Extract Multi-Scale Information in Medical Image Segmentation1 Sep 2025
- 2025Analysis of the Compaction Behavior of Textile Reinforcements in Low-Resolution In-Situ CT Scans via Machine-Learning and Descriptor-Based Methods13 Aug 2025
- 2025SharpXR: Structure-Aware Denoising for Pediatric Chest X-Rays11 Aug 2025
- 2025Hybrid(Transformer+CNN)-based Polyp Segmentation8 Aug 2025
- 2025Synthetic Data-Driven Multi-Architecture Framework for Automated Polyp Segmentation Through Integrated Detection and Mask Generation8 Aug 2025
- 2025SegDT: A Diffusion Transformer-Based Segmentation Model for Medical Imaging21 Jul 2025
- 2025Unit-Based Histopathology Tissue Segmentation via Multi-Level Feature Representation16 Jul 2025
- 2025U-RWKV: Lightweight medical image segmentation with direction-adaptive RWKV15 Jul 2025
- 2025HANS-Net: Hyperbolic Convolution and Adaptive Temporal Attention for Accurate and Generalizable Liver and Tumor Segmentation in CT Imaging15 Jul 2025
- 2025Ensemble of Weak Spectral Total Variation Learners: a PET-CT Case Study11 Jul 2025
- 2025CL-Polyp: A Contrastive Learning-Enhanced Network for Accurate Polyp Segmentation9 Jul 2025
- 2025Mamba Guided Boundary Prior Matters: A New Perspective for Generalized Polyp Segmentation2 Jul 2025
- 2025Self-Supervised Learning for Image Segmentation: A Comprehensive Survey19 May 2025
- 2025PRS-Med: Position Reasoning Segmentation in Medical Imaging17 May 2025
- 2025ROIsGAN: A Region Guided Generative Adversarial Framework for Murine Hippocampal Subregion Segmentation15 May 2025
- 2025An incremental algorithm for non-convex AI-enhanced medical image processing13 May 2025
- 2025FocusNet: Transformer-enhanced Polyp Segmentation with Local and Pooling Attention18 Apr 2025
- 2025AgentPolyp: Accurate Polyp Segmentation via Image Enhancement Agent15 Apr 2025
50 newest of 211 All 211 (JSON)
- 2024Vivim: a Video Vision Mamba for Medical Video Segmentationcited by 51
- 2024ProMamba: Prompt-Mamba for polyp segmentationcited by 12
- 2024SAM-Mamba: Mamba Guided SAM Architecture for Generalized Zero-Shot Polyp Segmentationcited by 7
- 2025A Reverse Mamba Attention Network for Pathological Liver Segmentationcited by 3
- 2025Mamba Guided Boundary Prior Matters: A New Perspective for Generalized Polyp Segmentationcited by 1
- 2025MSV-Mamba: A Multiscale Vision Mamba Network for Echocardiography Segmentationcited by 0
- 20263D Segment Anything Model with Visual Mamba for Diagnosing Placenta Accreta Spectrumcited by 0
- 20263D Segment Anything Model with Visual Mamba for Diagnosing Placenta Accreta Spectrum30 May 2026
- 2025Mamba Guided Boundary Prior Matters: A New Perspective for Generalized Polyp Segmentation2 Jul 2025
- 2025A Reverse Mamba Attention Network for Pathological Liver Segmentation23 Feb 2025
- 2025MSV-Mamba: A Multiscale Vision Mamba Network for Echocardiography Segmentation13 Jan 2025
- 2024SAM-Mamba: Mamba Guided SAM Architecture for Generalized Zero-Shot Polyp Segmentation11 Dec 2024
- 2024ProMamba: Prompt-Mamba for polyp segmentation20 Mar 2024
- 2024Vivim: a Video Vision Mamba for Medical Video Segmentation25 Jan 2024
- 2023Ambiguous Medical Image Segmentation using Diffusion Modelscited by 92
- 2023Certification of Deep Learning Models for Medical Image Segmentationcited by 4
- 2024On Instabilities of Unsupervised Denoising Diffusion Models in Magnetic Resonance Imaging Reconstructioncited by 1
- 2025SegDT: A Diffusion Transformer-Based Segmentation Model for Medical Imagingcited by 1
- 2024Structure-Aware Stylized Image Synthesis for Robust Medical Image Segmentationcited by 0
- 2026POWDR: Pathology-preserving Outpainting with Wavelet Diffusion for 3D MRIcited by 0
- 2026POWDR: Pathology-preserving Outpainting with Wavelet Diffusion for 3D MRI14 Jan 2026
- 2025SegDT: A Diffusion Transformer-Based Segmentation Model for Medical Imaging21 Jul 2025
- 2024Structure-Aware Stylized Image Synthesis for Robust Medical Image Segmentation5 Dec 2024
- 2024On Instabilities of Unsupervised Denoising Diffusion Models in Magnetic Resonance Imaging Reconstruction23 Jun 2024
- 2023Certification of Deep Learning Models for Medical Image Segmentation5 Oct 2023
- 2023Ambiguous Medical Image Segmentation using Diffusion Models10 Apr 2023
- 2025PRS-Med: Position Reasoning Segmentation in Medical Imaging17 May 2025
- 2021TransFuse: Fusing Transformers and CNNs for Medical Image Segmentationcited by 258
- 2021Polyp-PVT: Polyp Segmentation with Pyramid Vision Transformerscited by 159
- 2021DS-TransUNet:Dual Swin Transformer U-Net for Medical Image Segmentationcited by 126
- 2021Shallow Attention Network for Polyp Segmentationcited by 107
- 2022Video Polyp Segmentation: A Deep Learning Perspectivecited by 81
- 2021Automatic Polyp Segmentation via Multi-scale Subtraction Networkcited by 77
- 2021Progressively Normalized Self-Attention Network for Video Polyp Segmentationcited by 75
- 2021HarDNet-MSEG: A Simple Encoder-Decoder Polyp Segmentation Neural Network that Achieves over 0.9 Mean Dice and 86 FPScited by 71
- 2021UACANet: Uncertainty Augmented Context Attention for Polyp Segmentationcited by 61
- 2021TransAttUnet: Multi-level Attention-guided U-Net with Transformer for Medical Image Segmentationcited by 60
- 2022TAPE: Task-Agnostic Prior Embedding for Image Restorationcited by 54
- 2021MSRF-Net: A Multi-Scale Residual Fusion Network for Biomedical Image Segmentationcited by 53
12 most cited of 196 All 196 (JSON)
- 2026LightMIS: Ultra-Lightweight Medical Image Segmentation Without a Stage-Wise Decoder23 Sep 2026
- 2026InstEditSeg: Instruction-Driven Image Editing for Polyp and Skin Lesion Segmentation2 Sep 2026
- 2026Exploring SAM Supervision for Fine-Grained UAV Target Segmentation under Data Scarcity4 Jul 2026
- 2026Does Your ViT Still Need U-Net for Segmentation?30 Jun 2026
- 2026AerialFusionMapNet: Online HD Map Construction with Aerial-Onboard BEV Fusion23 Jun 2026
- 2026Learning a Sampling-Free Variational DNN Plugin from Tiny Training Sets to Refine OOD Segmentation With Uncertainty Estimation14 Jun 2026
- 2026Physics-Constrained Neural Surrogate for Domain Growth Prediction in Systems with Conserved Kinetics9 Jun 2026
- 2026SWARD: Stochastic Window-Attention-Based Relational Distillation for Cross-Architectural Semantic Segmentation31 May 2026
- 2026Learning Ego-Centric BEV Representations from a Perspective-Privileged View: Cross-View Supervision for Online HD Map Construction12 May 2026
- 2026Sharpening Lightweight Models for Generalized Polyp Segmentation: A Boundary Guided Distillation from Foundation Models20 Apr 2026
- 2026WILD-SAM: Phase-Aware Expert Adaptation of SAM for Landslide Detection in Wrapped InSAR Interferograms16 Apr 2026
- 2026OsteoFlow: Lyapunov-Guided Flow Distillation for Predicting Bone Remodeling after Mandibular Reconstruction23 Mar 2026
12 newest of 196 All 196 (JSON)