Model-Agnostic Interpretability of Machine Learning
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Abstract (arXiv)
Understanding why machine learning models behave the way they do empowers both system designers and end-users in many ways: in model selection, feature engineering, in order to trust and act upon the predictions, and in more intuitive user interfaces. Thus, interpretability has become a vital concern in machine learning, and work in the area of interpretable models has found renewed interest. In some applications, such models are as accurate as non-interpretable ones, and thus are preferred for their transparency. Even when they are not accurate, they may still be preferred when interpretability is of paramount importance. However, restricting machine learning to interpretable models is often a severe limitation. In this paper we argue for explaining machine learning predictions using model-agnostic approaches. By treating the machine learning models as black-box functions, these approaches provide crucial flexibility in the choice of models, explanations, and representations, improving debugging, comparison, and interfaces for a variety of users and models. We also outline the main challenges for such methods, and review a recently-introduced model-agnostic explanation approach (LIME) that addresses these challenges.
Key facts. Cited by 219 papers in the map (data through 14 Oct 2026). First posted on arXiv 16 Jun 2016.
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Citing papers per year: 2018: 1; 2019: 0; 2020: 0; 2021: 54; 2022: 36; 2023: 51; 2024: 53; 2025: 19; 2026: 5.
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- 2022Interpretable and Generalizable Graph Learning via Stochastic Attention Mechanismcited by 171
- 2022The Disagreement Problem in Explainable Machine Learning: A Practitioner's Perspectivecited by 159
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- 2023Appropriate Reliance on AI Advice: Conceptualization and the Effect of Explanationscited by 83
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- 2026Verifying Machine Learning Interpretability Requirements through Provenance23 Apr 2026
- 2026A Practical Guide Towards Interpreting Time-Series Deep Clinical Predictive Models: A Reproducibility Study25 Mar 2026
- 2025You Only Train Once: Differentiable Subset Selection for Omics Data19 Dec 2025
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