AutoMedBench: Towards Medical AutoResearch with Agentic AI Models
On the map: LLM agents and tool use → Medical and scientific domain agents
Abstract (arXiv)
Autonomous agents are increasingly expected to support end-to-end medical-AI research workflows, moving beyond isolated prediction tasks or short-form clinical question answering. However, existing medical agent benchmarks primarily evaluate final outputs, providing limited visibility into agent behavior within the research process. To address this gap, we present AutoMedBench, a workflow-aware benchmark for autonomous medical-AI research across diverse medical imaging and multimodal inference tasks, organizing agent execution into a unified five-stage workflow (S1-S5): Plan, Setup, Validate, Inference, and Submit. It comprises long-horizon tasks with each run averaging 33 agent turns, spanning five research tracks: segmentation, image enhancement, visual question answering (VQA), report generation, and lesion detection. Each task is evaluated under two difficulty tiers, Lite and Standard, which use the same data and metrics but differ in the amount of task-brief scaffolding, and each run is scored using both final task performance and S1-S5 stage scores, enabling stage-level analysis from the initial task brief to the final submitted artifact. Across thousands of recorded runs, stage-level scoring reveals that Validate is the weakest workflow stage on average, whereas Setup is the strongest, suggesting that current agents are better at making pipelines executable than at verifying their reliability. Post-run error analysis further shows that verification and submission failures dominate tagged errors, accounting for 37.7% and 38.1% of fired codes respectively, whereas task-understanding errors are rare at 0.9%, and runs with one fired error code have a 48% lower overall score than runs with no error code on average.
Key facts. Cited by 4 papers in the map (data through 14 Oct 2026). Placed in Medical and scientific domain agents, one of 16 directions in LLM agents and tool use. Builds on 42 of its 75 references that are in the map. First posted on arXiv 1 Jun 2026.
Builds on
42 of 75 references.
Closest ancestors · 5
Same direction, newest first
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- 2024AgentClinic: a multimodal agent benchmark to evaluate AI in simulated clinical environments13 May
Other references · 37
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- 2022Large Language Models Encode Clinical Knowledgecited by 1,830
- 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,356
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- 2023AgentBench: Evaluating LLMs as Agentscited by 1,267
- 2017A Survey on Deep Learning in Medical Image Analysiscited by 1,186
25 more
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- 2021Medical Visual Question Answering: A Surveycited by 93
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- 2025MedHELM: Holistic Evaluation of Large Language Models for Medical Taskscited by 64
- 2025MedFrameQA: A Multi-Image Medical VQA Benchmark for Clinical Reasoningcited by 34
- 2026HealthBench Professional: Evaluating Large Language Models on Real Clinician Chatscited by 26
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Built on by
Citing papers per year: 2026: 4.
4 papers.
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- 2026BaT: Towards Self-Evolving Medical Research Agent with Stage Rubrics17 Aug 2026
- 2026The Path to Self-Evolving Clinical Systems: Scaling Medical Agents from Assistance to Autonomy13 Jul 2026
- 2026Towards Autonomous and Auditable Medical Imaging Model Development12 Jul 2026
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