mlsanityData to 14 Oct 2026

HealthBench Professional: Evaluating Large Language Models on Real Clinician Chats

arXiv 2604.27470 ↗First posted 30 Apr 2026cs.CLcited by 26

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Abstract (arXiv)

Millions of clinicians use ChatGPT to support clinical care, but evaluations of the most common use cases in model-clinician conversations are limited. We introduce HealthBench Professional, an open benchmark for evaluating large language models on real tasks that clinicians bring to ChatGPT in the course of their work. The benchmark is organized around three common use cases central to clinical practice: care consult, writing and documentation, and medical research. Each example includes a physician-authored conversation with ChatGPT for Clinicians and is scored via rubrics written and iteratively adjudicated by three or more physicians across three phases. HealthBench Professional examples were carefully selected for quality, representativeness, and difficulty for OpenAI's current frontier models, to enable continued measurement of progress. Difficult examples for recent OpenAI models were enriched by roughly 3.5 times relative to the candidate pool of 15,079 examples. Additionally, about one-third of examples involve physicians conducting deliberate adversarial testing of models. As a strong baseline, we also collected human physician responses for all tasks (unbounded time, specialist-matched, web access). The best scoring system, GPT-5.4 in ChatGPT for Clinicians, outperforms base GPT-5.4, all other models, and human physicians. We hope HealthBench Professional provides the healthcare AI community a measure to track frontier model progress in real-world clinical tasks and build systems that clinicians can trust to improve care.

Key facts. Cited by 26 papers in the map (data through 14 Oct 2026). Builds on 26 of its 37 references that are in the map. First posted on arXiv 30 Apr 2026.

Builds on

26 of 37 references.

References · 26

  1. 2024GPT-4o System Cardcited by 4,588
  2. 2020What Disease does this Patient Have? A Large-scale Open Domain Question Answering Dataset from Medical Examscited by 1,356
  3. 2019PubMedQA: A Dataset for Biomedical Research Question Answeringcited by 1,288
  4. 2024Length-Controlled AlpacaEval: A Simple Way to Debias Automatic Evaluatorscited by 897
  5. 2023Large Language Modelscited by 780
  6. 2022MedMCQA : A Large-scale Multi-Subject Multi-Choice Dataset for Medical domain Question Answeringcited by 543
  7. 2025HealthBench: Evaluating Large Language Models Towards Improved Human Healthcited by 429
  8. 2024Benchmarking Retrieval-Augmented Generation for Medicinecited by 331
  9. 2023Adapted Large Language Models Can Outperform Medical Experts in Clinical Text Summarizationcited by 246
  10. 2024Capabilities of Gemini Models in Medicinecited by 237
  11. 2025MedXpertQA: Benchmarking Expert-Level Medical Reasoning and Understandingcited by 224
  12. 2023ACI-BENCH: a Novel Ambient Clinical Intelligence Dataset for Benchmarking Automatic Visit Note Generationcited by 118
14 more
  1. 2023EHRSHOT: An EHR Benchmark for Few-Shot Evaluation of Foundation Modelscited by 105
  2. 2025Recursive Language Modelscited by 104
  3. 2024MEDEC: A Benchmark for Medical Error Detection and Correction in Clinical Notescited by 80
  4. 2024MedCalc-Bench: Evaluating Large Language Models for Medical Calculationscited by 70
  5. 2025MedAgentBench: A Realistic Virtual EHR Environment to Benchmark Medical LLM Agentscited by 62
  6. 2023MedAlign: A Clinician-Generated Dataset for Instruction Following with Electronic Medical Recordscited by 56
  7. 2024Explaining Length Bias in LLM-Based Preference Evaluationscited by 49
  8. 2025MedCaseReasoning: Evaluating and learning diagnostic reasoning from clinical case reportscited by 36
  9. 2025LLMEval-Med: A Real-world Clinical Benchmark for Medical LLMs with Physician Validationcited by 34
  10. 2025MoReBench: Evaluating Procedural and Pluralistic Moral Reasoning in Language Models, More than Outcomescited by 23
  11. 2026HealthAdminBench: Evaluating Computer-Use Agents on Healthcare Administration Taskscited by 13
  12. 2026MedDialogRubrics: A Comprehensive Benchmark and Evaluation Framework for Multi-turn Medical Consultations in Large Language Modelscited by 12
  13. 2024A dataset and benchmark for hospital course summarization with adapted large language modelscited by 11
  14. 2025Teaching large language models to reason like expert diagnosticianscited by 2

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Citing papers per year: 2026: 26.

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  1. 2026PhysicianBench: Evaluating LLM Agents in Real-World EHR Environmentscited by 21
  2. 2026Quantifying and Mitigating Premature Closure in Frontier LLMscited by 4
  3. 2026AutoMedBench: Towards Medical AutoResearch with Agentic AI Modelscited by 4
  4. 2026Reinforcement Learning Towards Broadly and Persistently Beneficial Modelscited by 4
  5. 2026K-Bench: measuring model performance on real scientific agent requestscited by 2
  6. 2026Accelerating Scientific Research with Gemini in the Real-Worldcited by 2
  7. 2026Toward Workflow-Aware Benchmarking for Healthcare NLP Agentscited by 1
  8. 2026AcuityBench: Evaluating Clinical Acuity Identification and Uncertainty Alignmentcited by 0
  9. 2026When Cases Get Rare: A Retrieval Benchmark for Off-Guideline Clinical Question Answeringcited by 0
  10. 2026MDIA: A Multi-Agent Diagnostic Intelligence Pipeline on HealthBench Professionalcited by 0
  11. 2026Generalistic or Specific Embeddings, Which is Better? An Empirical Study on Search for Clinical Coding in Non-English Languagescited by 0
  12. 2026MedRealMM: A Real-World Multimodal Benchmark for Chinese Online Medical Consultationcited by 0
14 more
  1. 2026Agentic systems for breast cancer treatment recommendationscited by 0
  2. 2026Cura 1T: Specialized Model for Agentic Healthcarecited by 0
  3. 2026PatientAgentBench: A Benchmark Framework for Evaluating Patient-Facing Health AI Agentscited by 0
  4. 2026Towards Expert-level Medical AI for Real-time Video Consultationscited by 0
  5. 2026Position: Medical AI Neglects Real Treatment Outcomescited by 0
  6. 2026HealMed: Multilingual Evaluation of Large Language Models in Medicinecited by 0
  7. 2026ExecRubrics: Executable Tool-Augmented Rubrics for Verifiable and Efficient Long-Form Evaluationcited by 0
  8. 2026Dense Clinical Contrasts Enhance Medical Knowledge Updating in Large Language Modelscited by 0
  9. 2026Fathom-Vaidya: Advancing Medical Reasoning with Rubric-Based Rewardscited by 0
  10. 2026RSI-Master: Structuring Experiments to Guide Autonomous Model Improvementcited by 0
  11. 2026KlinikeBench: Evaluating Language Models Beyond Diagnostic Accuracycited by 0
  12. 2026Scoring Higher, Answering Worse: Mitigating Reward Hacking in Rubric-Based RL via Protocol-Level Rubricscited by 0
  13. 2026HuatuoGPT-3: RL-Only Domain Adaptation from Base Modelscited by 0
  14. 2026Clinician use of language models diverges from how the models are evaluatedcited by 0