HEARTS: Benchmarking LLM Reasoning on Health Time Series
On the map: LLM reasoning → Clinical and biomedical applications
Abstract (arXiv)
The rise of large language models (LLMs) has shifted time series analysis from narrow analytics to general-purpose reasoning. Yet, existing benchmarks cover only a small set of health time series modalities and tasks, failing to reflect the diverse domains and extensive temporal dependencies inherent in real-world physiological modeling. To bridge these gaps, we introduce HEARTS (Health Reasoning over Time Series), a unified benchmark for evaluating hierarchical reasoning capabilities of LLMs over general health time series. HEARTS integrates 16 real-world datasets across 12 health domains and 20 signal modalities, and defines a comprehensive taxonomy of 110 tasks grouped into four core capabilities: Perception, Inference, Generation, and Deduction. Evaluating 16 state-of-the-art LLMs on more than 20K test samples reveals intriguing findings. First, LLMs substantially underperform specialized models, and their performance is only weakly related to general reasoning scores. Moreover, LLMs often rely on simple heuristics and struggle with multi-step temporal reasoning. Finally, performance declines with increasing temporal complexity, with similar failure modes within model families, indicating that scaling alone is insufficient. By making these gaps measurable, HEARTS provides a standardized testbed and living benchmark for developing next-generation LLM agents capable of reasoning over diverse health signals.
Key facts. Cited by 11 papers in the map (data through 14 Oct 2026). Placed in Clinical and biomedical applications, one of 17 directions in LLM reasoning. Builds on 31 of its 95 references that are in the map. First posted on arXiv 25 Feb 2026.
Builds on
31 of 95 references.
References · 31
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Built on by
Citing papers per year: 2026: 11.
11 papers.
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- 2026Signal or Noise? Understanding Generative Models for Real-World Sensor Time Seriescited by 2
- 2026An AI Co-Data-Scientist for Prioritizing Candidate Biomarkers from Wearable Sensor Datacited by 1
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- 2026TimeThink: Eliciting Compositional Reasoning in Timeseries Large Language Models11 Sep 2026
- 2026BrainBench: Benchmarking Large Language Models for Comprehensive EEG Understanding4 Aug 2026
- 2026Inertia-1: An Open Exploration of Wearable Motion Foundation Models7 Jul 2026
- 2026Signal or Noise? Understanding Generative Models for Real-World Sensor Time Series5 Jul 2026
- 2026GlucoFM: A Dual-Stream Foundation Model for Continuous Glucose Monitoring29 May 2026
- 2026TimeSRL: Generalizable Time-Series Behavioral Modeling via Semantic RL-Tuned LLMs -- A Case Study in Mental Health20 May 2026
- 2026An AI Co-Data-Scientist for Prioritizing Candidate Biomarkers from Wearable Sensor Data16 Apr 2026
- 2026OSF: On Pre-training and Scaling of Sleep Foundation Models27 Feb 2026
- 2026SleepLM: Natural-Language Intelligence for Human Sleep27 Feb 2026
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